A National Leader in Pediatric Research

 

The Research Institute at Nationwide Children's Hospital works to enhance the health of children by engaging in high-quality, cutting-edge research. The work we do every day is dedicated to improving the health of Children and their families in Central Ohio and beyond.

$7 Million NIH Grant Designates Nationwide Children’s as a Wellstone Center to Advance Muscular Dystrophy Research

A $5 million grant from the National Institutes of Health (NIH) will help researchers at Nationwide Children’s Hospital translate new scientific findings and technological developments into novel treatments for the muscular dystrophies. The grant designates Nationwide Children’s Hospital as a Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, one of three national award recipients in 2010.
Read more :: Nationwide Children's Designated as Wellstone Center

Clinical Research Conference
The Clinical Research Continuum — How to be Successful in Your Journey

Nationwide Children’s Hospital, Education Center, Stecker Auditorium, Columbus, OH, Friday, October 15, 2010

Learn more about this conference and register

Spinal Muscular Atrophy May Also Affect the Heart

Along with skeletal muscles, it may be important to monitor heart function in patients with spinal muscular atrophy (SMA). These are the findings from a study conducted by Nationwide Children’s Hospital and published online ahead of print in Human Molecular Genetics. This is the first study to report cardiac dysfunction in mouse models of SMA.
 

Parent Project Muscular Dystrophy Awards $600K to Nationwide Children’s Hospital for Gene Therapy Study

 
Parent Project Muscular Dystrophy (PPMD), the largest non-profit organization in the United States focused on finding a cure for Duchenne muscular dystrophy (Duchenne), announced that PPMD will award a $600,000 grant to Nationwide Children’s Hospital in Columbus, Ohio to conduct clinical testing of a promising gene therapy technique for muscle disease.

New National Study Examines U.S. High School Sports-Related Fractures

A new study found that 95 percent of fractures required costly diagnostic imaging, including X-rays, MRIs and CT scans, and 16 percent required surgical repair.

Read more :: New National Study Examines U.S. High School Sports-Related Fractures

New National Study Finds Decrease in Pediatric Injuries Associated with Household Cleaners

A new study found that from 1990-2006, an estimated 267,269 children younger than 6 years were treated in U.S. hospital emergency departments for injuries attributable to household cleaning products.
 

Pilot Study Supports Adolescent Diabetes Patients through Personalized Text Messages

An endocrinologist at Nationwide Children’s Hospital, has developed and completed a pilot study that uses weekly, customized text messages to remind adolescent diabetes patients about their personal treatment activities.
 

New Mouse Model of DMD More Accurately Mimics Human Disease

Therapies to treat Duchenne muscular dystrophy may sooner progress toward clinical trials thanks to a more realistic mouse model that mimics the human disease better than existing models.  The new framework is detailed in a Nationwide Children’s Hospital study that appears in Science Translational Medicine.

Could Waiting Two Minutes Improve How Newborns Recover from Heart Surgery?

A newly funded study is set to determine whether waiting two minutes to clamp a newborn’s umbilical cord after delivery could improve how well he or she recovers from corrective heart surgery.

Read more :: Could Waiting Two Minutes Improve How Newborns Recover from Heart Surgery?

Sickle Cell Patients Should Be Better Monitored for Constipation Prevention

Not all patients with sickle cell disease receive laxatives after being treated with narcotics, despite recommendations from a collaborative panel of pediatric experts.  These are the findings from a Nationwide Children’s Hospital study examining patients from 29 pediatric hospitals, and appearing in Pediatric Blood & Cancer.

Read more :: Sickle Cell Patients Should Be Better Monitored for Constipation Prevention

New Potential Autism Susceptibility Genes Identified

Several newly-identified genes may make children more susceptible to developing autism, according to a study from the Autism Genome Project, an international consortium that includes Nationwide Children’s Hospital. These second-phase results appear in Nature.

Read more :: New Potential Autism Susceptibility Genes Identified

Nationwide Children’s Hospital Receives Palliative Care Research Grant

Cynthia Gerhardt, PhD, awarded grant for research to improve care of seriously ill patients

Read more :: Nationwide Children’s Hospital Receives Palliative Care Research Grant

Modified Measles Virus Shows Potential for Treating Childhood Brain Tumors

The use of modified measles virus may represent a new treatment for a childhood brain tumor known as medulloblastoma, according to a new study appearing in Neuro-Oncology.  Medulloblastoma is the most common malignant central nervous system tumor of childhood, accounting for about 20 percent of pediatric brain tumors.

Listen Now: Podcasts Dedicated to the Latest Neuromuscular Research

Hosted by Kevin Flanigan, MD, "This Month in Muscular Dystrophy" podcasts highlight the latest in muscular dystrophy and other inherited neuromuscular disease research.  During each podcast, authors of recent publications discuss how their work improves our understanding of inherited neuromuscular diseases, and what their work might mean for treatment of these diseases.

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Research News and Highlights
Read more news and highlights from our research faculty