Methods Core
This group addresses methodological and statistical challenges that impede progress toward effectively reducing the youth suicide rate.
The overall goal of the MC is to strengthen the rigor, quality, and implementation success of the research projects within ASPIRES while simultaneously developing and promoting innovative methods for suicide prevention research.
Christopher Bartlett, PhD
Christopher.Bartlett@NationwideChildrens.org
Chris Bartlett's lab seeks to identify genetic factors for language impairments. As animal models of language development are of limited utility, we examine DNA from families segregating specific language impairment or autism as part of two separate but interacting projects. These projects are heavily interdisciplinary, utilizing a wide range of molecular and computational methods developed in-house and though close collaborations with experts in statistics and computer science. We hope that use of genetics will allow for identification of at-risk children to promote early intervention.
Ann McAlearney
Ann Scheck McAlearney, ScD, MS, is Associate Dean for Health Services Research, Distinguished Professor of Family and Community Medicine, and Executive Director of CATALYST, the Center for the Advancement of Team Science, Analytics, and Systems Thinking in Health Services and Implementation Science Research in the College of Medicine (COM) at The Ohio State University (OSU). She also holds appointments in the College of Public Health and the Departments of Biomedical Informatics and Pediatrics in COM at OSU. She has over 30 years of health services research experience during which she has been actively involved in both performing research and disseminating research results to academic and practitioner audiences. Dr. McAlearney is internationally known for her expertise in both qualitative and mixed methods analyses, and has been continuously funded for over 20 years. She has authored over 300 peer-reviewed publications, 11 books/edited books and more than 100 book chapters. Dr. McAlearney has served as a grant reviewer for nearly 20 years including for the Agency for Healthcare Research and Quality, National Institutes of Health, Patient-Centered Outcomes Research Institute, and the National Science Foundation. In addition to co-leading the Center to STOP-COVID at OSU (U54), Dr. McAlearney leads an R01 focused on applying management practices to prevent transmission of healthcare-associated infections. Her ongoing research focuses on addressing care disparities, information technology innovations in health care, population health management, quality improvement and organizational development. Dr. McAlearney received her undergraduate and graduate degrees from Stanford University and Harvard University’s T.H. Chan School of Public Health.
Guy Brock
Dr. Guy Brock is an Associate Professor in the Department of Biomedical Informatics, The Ohio State University College of Medicine (OSU-COM). He serves as Associate Director of the Center for Biostatistics, Director of the Biostatistics Resource at Nationwide Children’s Hospital (BRANCH), and Director of the Biostatistics, Epidemiology, and Research Design (BERD) Core of the Center for Clinical Translational Science (CCTS). He has taken a leadership role in promoting and maintaining rigorous scientific conduct at OSU and NCH, which includes obtaining supplemental funding for a course devoted to rigor, reproducibility, design, and data analysis. His methodological research funded by the NIH includes multistate transition models, competing risks, and statistical bioinformatics (cluster validation, data integration, missing value imputation). Dr. Brock co-leads the Methods Core for ASPIRES, which provides study design, informatics, and data analytic support for ASPIRES projects and investigators. He is also active in using secondary data for research, including claims data, electronic medical records, cohort studies, and registry data. Example funded projects include identifying high suicide risk periods for youths in public service systems and examining determinants and consequences of guideline concordant care on low-income children with depression in the U.S. He also serves as the lead biostatistician on multiple ongoing clinical trials, ranging from early phase studies to community-based pragmatic interventions incorporating both efficacy and implementation outcomes.