Viral Vector Core :: The Research Institute at Nationwide Children's Hospital

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Viral Vector Core & Clinical Manufacturing Facility

Viral Vector Core

The Viral Vector Core supplies recombinant adeno-associated virus (rAAV) and recombinant adenovirus (rAd) vectors of uniform quality to individual research laboratories. The Core is a full-service facility, capable of generating vectors beginning with a cDNA sequence and ending with the synthesis and purification of gene transfer vectors that have passed rigorous quality control assays.

The Core now supports production of six rAAV vector serotypes (rAAV1, rAAV2, rAAV5, rAAV6, rAAV8 and rAAV9), and offers retroviral gene transfer vectors through a collaboration with The Vector Production Facility at Cincinnati Children's Hospital.

Clinical Manufacturing Facility

In 2009, the Viral Vector Core established a current Good Manufacturing Practice (cGMP) Production Facility, also konwn as the Clinical Manufacturing Facility (CMP).  The CMP specializes in the production of recombinant Adeno-Associated viral vectors (rAAV) for use by faculty at Nationwide Children's Hospital, The Ohio State University Medical Center and external academic collaborators. 

Visit the Clinical Manufacturing Facility site

Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000