Viral Vector Core

The Viral Vector Core supplies recombinant adeno-associated virus (rAAV) and recombinant adenovirus (rAd) vectors of uniform quality to individual research laboratories. The Core is a full-service facility, capable of generating vectors beginning with a cDNA sequence and ending with the synthesis and purification of gene transfer vectors that have passed rigorous quality control assays.

The Core now supports production of six rAAV vector serotypes (rAAV1, rAAV2, rAAV5, rAAV6, rAAV8 and rAAV9), and offers retroviral gene transfer vectors through a collaboration with the Viral Vector Core at Cincinnati Children’s Hospital Medical Center.

The Core is in the process of building a Good Manufacturing Practice (GMP) production facility for manufacture of clinical-grade rAAV vectors.