Viral Vector Core

The Viral Vector Core supplies recombinant adeno-associated virus (rAAV) and recombinant adenovirus (rAd) vectors of uniform quality to individual research laboratories. The Core is a full-service facility, capable of generating vectors beginning with a cDNA sequence and ending with the synthesis and purification of gene transfer vectors that have passed rigorous quality control assays.

The Core now supports production of six rAAV vector serotypes (rAAV1, rAAV2, rAAV5, rAAV6, rAAV8 and rAAV9), and offers retroviral gene transfer vectors through a collaboration with The Vector Production Facility at Cincinnati Children's Hospital.

Good Manufacturing Practice (GMP) Production Facility

In 2009, the Core established a current Good Manufacturing Practice (cGMP) Production Facility that specializes in the production of recombinant Adeno-Associated viral vectors (rAAV) for use by faculty at Nationwide Children's Hospital, The Ohio State University Medical Center and external academic collaborators.  Visit the GMP Facility site