Susan D. Reynolds, PhD :: Nationwide Children's Hospital, Columbus, Ohio

Susan D. Reynolds, PhD

Susan D. Reynolds, PhD

Center for Perinatal Research
Principal Investigator

Contact Information

700 Children's Drive
Columbus, OH 43205 [ map ]
PH: (614) 355-6716
Email Me


Susan D. Reynolds, PhD's research focuses on tissue stem cells that maintain the conducting airway epithelium. Previous work identified a basal cell subtype that functioned as a tissue stem cell in mice. Current research translates these findings to human airways and seeks to use the tissue stem cell as therapy for lung disease, including Cystic Fibrosis.


  • Female

Languages Spoken:

  • English

Research Interests

Education and Training

Graduate School

  • University of Rochester
    Date Completed: 06/05/1992


  • Center for Perinatal Research

Date of Appointment at Nationwide Children’s Hospital:

  • 01/01/2015


  • Ghosh M1, Ahmad S, Jian A, Li B, Smith RW, Helm KM, Seibold MA, Groshong SD, White CW, Reynolds SD. Human tracheobronchial basal cells. Normal versus remodeling/repairing phenotypes in vivo and in vitro. Am J Respir Cell Mol Biol. 2013 Dec;49(6):1127-34. doi: 10.1165/rcmb.2013-0049OC. PubMed ID: 23927678
  • Ghosh M1, Smith RW, Runkle CM, Hicks DA, Helm KM, Reynolds SD. Regulation of trachebronchial tissue-specific stem cell pool size. Stem Cells. 2013 Dec;31(12):2767-78. doi: 10.1002/stem.1440. PubMed ID: 23712882
  • Seibold MA1, Smith RW, Urbanek C, Groshong SD, Cosgrove GP, Brown KK, Schwarz MI, Schwartz DA, Reynolds SD. The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium. PLoS One. 2013;8(3):e58658. doi: 10.1371/journal.pone.0058658. Epub 2013 Mar 20. PubMed ID: 23527003
  • Brechbuhl HM1, Li B1, Smith RW1, Reynolds SD2. Epidermal growth factor receptor activity is necessary for mouse basal cell proliferation. Am J Physiol Lung Cell Mol Physiol. 2014 Nov 15;307(10):L800-10. doi: 10.1152/ajplung.00201.2014. Epub 2014 Sep 12. PubMed ID: 25217659
  • Smith MK1, Koch PJ, Reynolds SD. Direct and indirect roles for ß-catenin in facultative basal progenitor cell differentiation. Am J Physiol Lung Cell Mol Physiol. 2012 Mar 15;302(6):L580-94. doi: 10.1152/ajplung.00095.2011. Epub 2012 Jan 6. PubMed ID: 22227204
Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000