Nilay Shah, MD :: Nationwide Children's Hospital, Columbus, Ohio

Contact Information

Hematology & Oncology
700 Children's Dr
Columbus, OH 43205 [ map ]
PH: (614) 722-3550
FX: (614) 722-3369

Location Information for Patients

Main Campus


Dr. Nilay Shah is a physician scientist in the Center for Childhood Cancer and Blood Diseases at Nationwide Children’s Hospital. He also has a joint appointment as Assistant Professor in the Department of Pediatrics at The Ohio State University College of Medicine. His research focuses on embryonic cancers, including neuroblastoma and pediatric sarcomas. He specifically examines how these types of childhood cancers avoid normal development and become cancers. His goal is to identify signaling pathways as biomarkers for diagnosis and treatment. He also examines the functions of long noncoding RNAs in these diseases and how they can be modulated to affect disease response. He collaborates with the Department of Neuroscience at OSU to use zebrafish as a disease model. Dr. Shah is a graduate of the Honors Program in Medical Education at Northwestern University, earning his medical degree in 2003. Dr. Shah completed a residency in General Pediatrics in 2006 at the Children’s Hospital of Wisconsin, and a fellowship in Pediatric Hematology/Oncology at Johns Hopkins University and the National Cancer Institute in 2011. He also was a Research Instructor at the Lombardi Comprehensive Cancer Center at Georgetown University in Washington, D.C., prior to his arrival at Nationwide Children’s Hospital. In addition to his research, Dr. Shah sees pediatric oncology patients through the Division of Pediatric Hematology/Oncology at Nationwide Children’s Hospital.


  • Male

Languages Spoken:

  • English

Research Interests

Education and Training

Medical School

  • Northwestern University
    Date Completed: 06/20/2003


  • Children's Hospital of Wisconsin
    Date Completed: 06/30/2006


  • National Cancer Institute
    Date Completed: 06/30/2009


  • John Hopkins Hospital
    Date Completed: 06/30/2011


  • Pediatrics


  • Hematology & Oncology


  • Pediatric Hematology Oncology

Date of Appointment at Nationwide Children’s Hospital:

  • 09/27/2013


  • Sadik H, Korangath P, Nguyen N, Gyorffy B, Kumar R, Hedayati M, Teo WW, Panday H, Munoz TG, Menyhart O, Shah N, Pandita RK, Chang JC, DeWeese T, Change HY, Pandita TK, Sukumar S. 2016. HOXC10 expression supports the development of chemotherapy resistance by fine tuning DNA repair in breast cancer cells.  Cancer Research. Vol. Epub ahead of print, no. June: eEpub ahead of print.
  • Streby KA, Shah N, Ranalli M, Kunkler A, Cripe TP. 2015. Nothing but NET: A Review of Norepinephrine Transporter Expression and Efficacy of 131 I-MIBG Therapy.  Pediatric Blood Cancer. Vol. 1, no. January: 5-11.
  • Shah,Nilay; Wang,Jianjun; Selich-Anderson,Julia; Graham,Garrett; Siddiqui,Hasan; Li,Xin; Khan,Javed; Toretsky,Jeffrey. 2014. PBX1 Is a Favorable Prognostic Biomarker as It Modulates 13-cis Retinoic Acid-Mediated Differentiation in Neuroblastoma.  CLINICAL CANCER RESEARCH. Vol. 20, no. 16. (August): 4400-4412.
  • Shah N, Wang J, Selich-Anderson J, Graham G, Siddiqui H, Li X, Khan J, Toretsky JA. 2014. PBX1 is a Favorable Prognostic Biomarker as it Modulates 13-cis Retinoic Acid-mediated Differentiation in Neuroblastoma.  Clinical Cancer Research. Vol. 20, no. 16. (August): 4400-12.
  • Shah N, Jin K, Cruz LA, Park S, Sadik H, Cho S, Goswami CP, Nakshatri H, Gupta R, Chang HY, Zhang Z, Cimino-Mathews A, Cope L, Umbricht C, Sukumar S. 2013. HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERa and inducing IL-6 expression.  Cancer Research. Vol. 73, no. September: 5449-5458.
  • O'Neill A, Shah N, Zitomersky N, Ladanyi M, Shukla N, Uren A, Loeb D, Toretsky J. 2013. Insulin-like growth factor 1 receptor as a therapeutic target in ewing sarcoma: lack of consistent upregulation or recurrent mutation and a review of the clinical trial literature.  Sarcoma. Vol. 2013, no. January: e450478.
  • Bembea,Melania,M; Schwartz,Jamie,M; Shah,Nilay; Colantuoni,Elizabeth; Lehmann,Christoph,U; Kickler,Thomas; Pronovost,Peter; Strouse,John,J. 2013. Anticoagulation Monitoring during Pediatric Extracorporeal Membrane Oxygenation.  ASAIO JOURNAL. Vol. 59, no. 1. (January): 63-68.
  • Hung,Tiffany; Wang,Yulei; Lin,Michael,F; Koegel,Ashley,K; Kotake,Yojiro; Grant,Gavin,D; Horlings,Hugo,M; Shah,Nilay; Umbricht,Christopher; Wang,Pei; Wang,Yu; Kong,Benjamin; Langerod,Anita; Borresen-Dale,Anne-Lise; Kim,Seung,K; van de Vijver,Marc; Sukumar,Saraswati; Whitfield,Michael,L; Kellis,Manolis; Xiong,Yue; Wong,David,J; Chang,Howard,Y. 2011. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters.  NATURE GENETICS. Vol. 43, no. 7. (July): 621-U196.
  • Shah,Nilay; Sukumar,Saraswati. 2010. The Hox genes and their roles in oncogenesis.  NATURE REVIEWS CANCER. Vol. 10, no. 5. (May): 361-371.
  • Gupta,Rajnish,A; Shah,Nilay; Wang,Kevin,C; Kim,Jeewon; Horlings,Hugo,M; Wong,David,J; Tsai,Miao-Chih; Hung,Tiffany; Argani,Pedram; Rinn,John,L; Wang,Yulei; Brzoska,Pius; Kong,Benjamin; Li,Rui; West,Robert,B; van de Vijver,Marc,J; Sukumar,Saraswati; Chang,Howard,Y. 2010. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis.  NATURE. Vol. 464, no. 7291. (April): 1071-U148.
  • Shah,Nilay; Zambidis,Elias,T. 2009. False-Photosensitivity and Transient Hemiparesis Following High-Dose Intravenous and Intrathecal Methotrexate for Treatment of Acute Lymphoblastic Leukemia.  PEDIATRIC BLOOD & CANCER. Vol. 53, no. 1. (July): 103-105.
Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000