Nationwide Children’s Hospital is home to one of the largest networks of clinical neonatal care in the United States. The Section of Neonatology at Nationwide Children’s is an integral component of the neonatal program, which includes a full range of newborn care and innovative research programs, conducted through the division and in collaboration with the Center for Perinatal Research.
The section has developed a variety of innovative, unique programs, including the Comprehensive Center for Bronchopulmonary Dysplasia (BPD), Small Baby Program, Infant Feeding Disorders Program, and the Ohio Better Birth Outcomes (OBBO) initiative.
The BPD Center fosters relationships between the health care team and families of infants with BPD and includes both inpatient and outpatient services The interdisciplinary team consists of a core group of neonatologists, pulmonologists, nurse practitioners, nurses, nutritionists, occupational therapists, physical therapists, social workers, case managers, pharmacists, speech therapists, respiratory therapists, parent support staff and pediatricians. The composition of the team is designed to address the individualized, and often highly complex, needs of the infant and family.
The mission of the CCBPD team is two-fold: First, to serve each infant and family by using the latest evidence-based practice and research to continuously improve care, and second, to foster a physical and therapeutic environment that empowers the family to actively participate in the care of their child.
Sudarshan R. Jadcherla, MD, leads the IFDP, which consists of both a clinical component and a National Institutes of Health-funded research component. The IFDP is dedicated to improving quality of life for all infants through the development of personalized feeding-management strategies based on clinical and translational research. Our advanced care optimizes the outcomes for infants with feeding disorders, allowing them to go home sooner, while simultaneously lowering readmission rates. Our physician-scientists are using innovative approaches to find and treat the cause of feeding difficulty in developing infants.
In 2014, the Section of Neonatology developed a new, innovative program to address feeding and breathing issues in complex neonatal patients. The Neonatal Aerodigestive Program at Nationwide Children’s brings together a wide-range of specialists, including neonatologists, pulmonologists, otolaryngologists, radiologists, behavioral pediatricians, pediatricians, nursing, respiratory therapy, occupational therapy and speech therapy to develop comprehensive, holistic treatment plans for these complex patients.
Extreme prematurity is one of the leading causes of infant mortality. The Small Baby Program is changing that for babies born at less than 27-weeks’ gestation. At the heart of the program is a standardized protocol for care, developed by the Neonatology team at Nationwide Children’s and tested at the bedside, providing a uniform, interdisciplinary approach to the family centered care of extremely premature babies.
The Section of Neonatology is dedicated to the concept that to improve infant mortality, a concerted clinical and research effort must be undertaken to not only prevent prematurity and the complications of prematurity but also to excel at treating any complications that do occur. To achieve these goals, the section actively participates in OBBO, a partnership between Nationwide Children’s Hospital, all other hospital systems in Franklin County and health care providers as well as government and community organizations.
Leif D. Nelin, MD
Sudarshan Jadcherla, MD
Associate Division Chief
Kristina M. Reber, MD
Associate Division Chief
Edward G. Shepherd, MD
Selected Neonatology Clinical and Research Publications
Buhimschi IA, Nayeri UA, Zhao G, Shook LL, Pensalfini A, Funai EF, Bernstein IM, Glabe CG, Buhimschi CS. Protein misfolding, congophilia, oligomerization, and defective amyloid processing in preeclampsia. Science Translational Medicine. 2014 Jul;6(245):245ra92.
Chen B, Xue J, Meng X, Slutzky JL, Calvert AE, Chicoine LG. Resveratrol prevents hypoxia-induced arginase II expression and proliferation of human pulmonary artery smooth muscle cells via Akt-dependent signaling. American Journal of Physiology - Lung Cellular and Molecular Physiology. 2014 Aug;307(4):L317-25.
Hanin M, Nuthakki S, Malkar MB, Jadcherla SR. Safety and efficacy of oral feeding in infants with BPD on nasal CPAP. Dysphagia. 2015 April;30(2):121-7.
Jadcherla SR, Dail J, Malkar MB, McClead R, Kelleher K, Nelin L. Impact of process optimization and quality improvement measures on neonatal feeding outcomes at an all-referral neonatal intensive care unit. Journal of Parenteral and Enteral Nutrition. 2015 Mar 2.
Lopez-Medina E, Cantey JB, Sánchez PJ. The mortality of neonatal herpes simplex virus infection. Journal of Pediatrics. 2015 Jun;166(6):1529-32.
Murthy K, Yanowitz TD, DiGeronimo R, Dykes FD, Zaniletti I, Sharma J, Sullivan KM, Mirpuri J, Evans JR, Wadhawan R, Piazza A, Adams-Chapman I, Asselin JM, Short BL, Padula MA, Durand DJ, Pallotto EK, Reber KM. Short-term outcomes for preterm infants with surgical necrotizing enterocolitis. Journal of Perinatology. 2014 Oct;34(10):736-40.
Oza-Frank R, Kachoria R, Keim SA, Klebanoff MA. Provision of specific preconception care messages and associated maternal health behaviors before and during pregnancy. American Journal of Obstetrics and Gynecology. 2015 Mar;212(3):372.e1-8.
Slaughter JL, Stenger MR, Reagan PB, Jadcherla SR. Inhaled bronchodilator use for infants with bronchopulmonary dysplasia. Journal of Perinatology. 2015 Jan;35(1):61-6.
Talavera MM, Kralik N, Jin Y, Chen B, Liu Y, Nelin LD. Mitogen-activated protein kinase phosphatase-1 prevents lipopolysaccharide-induced apoptosis in immature rat intestinal epithelial cells. Pediatric Research. 2015 Aug;78(2):128-36.
Trittmann JK, Peterson E, Rogers LK, Chen B, Backes CH, Kelbanoff MA, Nelin LD. Plasma asymmetric dimethylarginine levels are increased in neonates with bronchopulmonary dysplasia-associated pulmonary hypertension. Journal of Pediatrics. 2015 Feb;166(2):230-3.
Center for Perinatal Research