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John R. Mytinger, MD

John R. Mytinger, MD

Physician Team

Neurology Residency

Physician Team

Contact Information

700 Children's Dr
Columbus, OH 43205 [ map ]
PH: (614) 722-4625
FX: (614) 722-4633


John R. Mytinger, MD, is an attending child neurologist at Nationwide Children’s and Assistant Professor of Clinical Pediatrics and Neurology at The Ohio State University College of Medicine. He completed his pediatric and child neurology residencies as well as his clinical neurophysiology and epilepsy fellowships at the University of Virginia. He has a special interest in infantile spasms and epileptic encephalopathy.


  • Male

Languages Spoken:

  • English

Education and Training

Medical School

  • Albany Medical College
    Date Completed: 05/26/2005


  • University of Virginia Health Systems
    Date Completed: 06/30/2007


  • University of Virginia Health Systems
    Date Completed: 06/30/2010


  • University of Virginia Health Systems
    Date Completed: 06/30/2011


  • Pediatrics


  • Neurology


  • Child Neurology
  • Clinical Neurophysiology
  • Neurology

Date of Appointment at Nationwide Children’s Hospital:

  • 07/01/2012


  • Mytinger JR, Bowden SA. 2015. Adrenal Function Testing Following Hormone Therapy for Infantile Spasms: Case Series and Review of Literature.  Front Neurol. Vol. 6, no. December: e259.
  • 1. Knupp KG, Coryell J, Nickels KC, Ryan N, Leister E, Loddenkemper T, Grinspan Z, Hartman AL, Kossoff EH, Gaillard WD, Mytinger JR, Joshi S, Shellhaas RA, Sullivan J, Dlugos D, Hamikawa L, Berg AT, Millichap J, Nordli DR Jr, Wirrell E; Pediatric Epilepsy Research Consortium. 2015. Response To Treatment In A Prospective National Infantile Spasms Cohort.  Ann Neurol. Vol. Ahead of Print, no. December: eAhead of Print.
  • Mytinger,John,R; Hussain,Shaun,A; Islam,Monica,P; Millichap,John,J; Patel,Anup,D; Ryan,Nicole,R; Twanow,Jaime-Dawn,E; Heyer,Geoffrey,L. 2015. Improving the inter-rater agreement of hypsarrhythmia using a simplified EEG grading scale for children with infantile spasms.  EPILEPSY RESEARCH. Vol. 116, no. October: 93-98.
  • Fedak EM, Patel AD, Heyer GL, Wood EG, Mytinger JR. 2015. Optimizing Care With a Standardized Management Protocol for Patients With Infantile Spasms.  Journal of Child Neurology. Vol. 30, no. 10. (September): 1340-1342.
  • Myitnger JR, Camfield P. 2015. Synthetic ACTH is not superior to prednisolone for infantile spasms – Randomized clinical trials and tribulations.  Pediatric Neurology. Vol. 53, no. 3. (September): 181-182.
  • Weber A*, Cole J*, Mytinger JR*. 2015. Infantile spasms respond poorly to topiramate.  Pediatric Neurology. Vol. 53, no. August: 130-134.
  • Mytinger, JR. 2015. Do Seizures Cause Developmental Delay? Can Treating The Seizures Help?. In Curbside Consultation in Pediatric Neurology, 1st Edition. 1st ed. Edited by Licht, DJ, Ryan, NR. Thorofare, NJ: SLACK Incorporated.
  • Mytinger, JR. 2015. Infantile Spasms. In The 5-Minute Pediatric Consult. 7th ed. Edited by Cabana, MD. Philidelphia, PA: Wolters Kluwer.
  • Brenton JN, Mytinger JR. 2015. The Sporadic Occurrence of Completely Lateralized Vertex Sharp Transients of Sleep Is a Normal Phenomenon: A Retrospective, Blinded, Case-Control Study.  J Clin Neurophysiol. Vol. 32, no. 2. (April): 171-174.
  • Wirrell EC, Shellhaas RA, Joshi C, Keator C, Kumar S, Mitchell WG; Pediatric Epilepsy Research Consortium (PERC). 2015. How should children with West syndrome be efficiently and accurately investigated? Results from the National Infantile Spasms Consortium.  Epilepsia. Vol. Ahead of Print, no. March: eAhead of Print.
  • Mytinger JR, Weber A, Heyer GL. 2015. The response to ACTH is determined early in the treatment of infantile spasms.  Epileptic Disorders. Vol. 17, no. 1. (March): 52-57.
  • Hussain SA, Kwong G, Millichap JJ, Mytinger JR, Ryan R, Matsumoto JH, Wu JY, Lerner JT, Raman Sankar R. 2014. Hypsarrhythmia assessment exhibits poor inter-rater reliability: a threat to clinical trial validity.  Epilepsia. Vol. 56, no. 1. (November): 77-81.
  • Mori M, Bartholomew D Martin L, Mytinger JR, Hickey S. 2014. m.8993T>G-associated Leigh syndrome with hypocitrullinemia on newborn screening.  Journal of Inherited and Metabolic Disease. Vol. 17, no. September: 47-51.
  • Mytinger JR, Heyer GL. 2014. Oral corticosteroid versus ACTH for infantile spasms – an unfinished story.  Pediatric Neurology. Vol. 51(1), no. July: 13-4.
  • Mytinger,John,R; Joshi,Sucheta. 2012. The Current Evaluation and Treatment of Infantile Spasms Among Members of the Child Neurology Society.  JOURNAL OF CHILD NEUROLOGY. Vol. 27, no. 10. (October): 1289-1294.
  • Mytinger,John,R; Quigg,Mark; Taft,William,C; Buck,Marcia,L; Rust,Robert,S. 2010. Outcomes in Treatment of Infantile Spasms With Pulse Methylprednisolone.  JOURNAL OF CHILD NEUROLOGY. Vol. 25, no. 8. (August): 948-953.
  • Shaheen,T; Volles,D; Calland,F; Sifri,C,D; Mytinger,J; Hagspiel,K; Sawyer,R; Bonatti,H. 2009. Cefepime-Associated Status Epilepticus in an ICU Patient with Renal Failure.  JOURNAL OF CHEMOTHERAPY. Vol. 21, no. 4. (August): 452-454.
  • Mytinger,John,R; Patterson,James,W; Thibault,Erin,S; Webb,Jeffrey; Saulsbury,Frank,T. 2008. Henoch-Schonlein Purpura Associated with Helicobacter pylori Infection in a Child.  PEDIATRIC DERMATOLOGY. Vol. 25, no. 6. (November): 630-632.
  • Mytinger JR, Blackman JA, Goodkin HP. 2008. Index of suspicion: Congenital Rett Syndrome.  Pediatrics in Review. Vol. 29, no. 7. (September): 243-248.
  • Mytinger,John,R; Blackman,James,A; Goodkin,Howard,P. 2008. Index of suspicion.  Pediatrics in review. Vol. 29, no. 7. (July): 243-248.
  • Cao,B,H; Mytinger,J,R; Huard,J. 2002. Adenovirus mediated gene transfer to skeletal muscle.  MICROSCOPY RESEARCH AND TECHNIQUE. Vol. 58, no. 1. (July): 45-51.
  • Qu-Petersen,Z,Q; Deasy,B; Jankowski,R; Ikezawa,M; Cummins,J; Pruchnic,R; Mytinger,J; Cao,B,H; Gates,C; Wernig,A; Huard,J. 2002. Identification of a novel population of muscle stem cells in mice: potential for muscle regeneration.  JOURNAL OF CELL BIOLOGY. Vol. 157, no. 5. (May): 851-864.
  • Khadilkar,R,V; Mytinger,J,R; Thomason,L,E; Runyon,S,L; Washicosky,K,J; Jinks,R,N. 2002. Central regulation of photosensitive membrane turnover in the lateral eye of Limulus. I. Octopamine primes the retina for daily transient rhabdom shedding.  VISUAL NEUROSCIENCE. Vol. 19, no. 3. (May): 283-297.

listen to Dr. Mytinger on PediaCast

Infantile Spasms – PediaCast 281

Mytinger Receives Infantile Spasms Heroes Award

The Child Neurology Foundation honored John Mytinger, MD with the 2015 Infantile Spasms Heroes Award.

The award is given each year to a physician and his or her institution who has demonstrated outstanding care of patients living with infantile spasm.

Read More »

Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000