Igor DvorchiK, Director of Biostatistics  :: Nationwide Children's Hospital, Columbus, Ohio

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Igor Dvorchik, Director of Biostatistics

Igor  Dvorchik, Director of Biostatistics

Biostatistics Core
Adjunct Faculty

Contact Information

700 Children's Drive
Columbus, OH 43205 [ map ]
Assistant: (614) 355-5647
E-mail Me

Biography

Igor Dvorchik, PhD, is director of Biostatistics at Nationwide Children’s Hospital. Modern biology often relies greatly on the science of biostatistics and its ability to direct experimental design, and collect, summarize and analyze scientific data. Dr. Dvorchik’s first priority will be to develop Nationwide Children’s Biostatistics Shared Resource (BSR), a service-oriented statistical unit available to all Nationwide Children’s investigators and physician scientists. This centralized biostatistics resource will further enhance Nationwide Children’s ability to advance quality, effectiveness and efficiency of pediatric clinical care. Before joining Nationwide Children’s, Dr. Dvorchik was associate professor of Surgery and Biostatistics at the University of Pittsburgh and directed the medical decision and research support groups in bioinformatics at the University of Pittsburgh Medical Center. Most recently, he served as a director of bioinformatics at Barrow Neurological Institute at Phoenix Children’s Hospital and as senior biostatistician. In these roles, he helped initiate multiple novel research studies and actively participated in clinical outcome research. While at the University of Pittsburgh, Dr. Dvorchik’s research focused on outcome and medical decision-making in cardiology, organ and bone marrow transplantation, intensive care and hepatology and liver cancer. His work helped clarify the effects of HLA matching between recipient and donor on liver transplantation outcome, helped elucidate the effects of immunosuppressive medications on the course of inflammatory bowel disease (IBD) and quantified the incidence of colorectal cancer in patients with IBD and primary sclerosing cholangitis. This research received international recognition and directly affected the medical care of these patient groups. Dr. Dvorchik’s work on outcome modeling for hepatocellular carcinoma played an important role in restating financial coverage for U.S. liver transplantation patients with this terminal disease. Dr. Dvorchik received a PhD in Electrophysics from Kharkov Railway University, Kharkov, USSR and a PhD in Applied Statistics and Monitoring and Control of Biological Systems Behavior from St. Petersburg Electrotechnical University, St. Petersburg, Russia. He has published 66 peer-reviewed manuscripts in various scientific journals including eight as the first and eight as a senior author. He is a co-author of three book chapters and has presented more than 20 abstracts at national and international meetings.

Gender:

  • Male

Languages Spoken:

  • English

Research Interests

Areas of Interest:

  • Modeling of medical and biological phenomena
  • Organization of clinical trials: Phases I - IV
  • Optimization of patient-donor characteristics matching in organ transplantation
  • Outcome Research
  • Development of methods of multivariate modeling and data preprocessing

Research Funding*:

  • Principal investigator, Rapid Cycle Outcome Research to Improve Clinical & Operational Outcomes, The Arizona Biomedical Research Commission and University of Arizona (2011-2013)

Education and Training

Undergraduate School

  • Kharkov State University
    Date Completed: 06/01/1979

Master's

  • Kharkov State University
    Date Completed: 06/01/1981

Post Doctoral

  • Kharkov Railway University
    Date Completed: 09/01/1989

Medical School

  • St.Petersburg Electrotechnical University
    Date Completed: 09/01/1997

Postgraduate

  • National Cancer Institute
    Date Completed: 09/01/1998

Department:

  • Battelle Center for Mathematical Medicine

Professional Experience

2012–present

  • Director of Biostatistics, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio

2010–2012

  • Adjunct Faculty, Department of Bioinformatics, Arizona State University

2010–2012

  • CNI Director of Bioinformatics, PCH Research Scientist, Senior Biostatistician, Children’s Neuroscience Institute, Phoenix Children’s Hospital

2006–2010

  • Research Associate Professor, Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh

2006–2010

  • Research Associate Professor in Surgery, Department of Surgery, University of Pittsburgh School of Medicine

2005–2010

  • Director, Medical Decision and Research Support Group, Bioinformatics, Thomas E. Starzl Transplantation Institute, University of Pittsburgh Medical Center

2005–2010

  • Adjunct Assistant Professor, Department of Primary Care, School of Health Related Professions, University of Medicine and Dentistry of NJ

2000–2010

  • Director, Section of Biostatistics T.E.Starzl Transplantation Institute, Department of Surgery, University of Pittsburgh Medical Center

1999–2006

  • Research Assistant Professor in Surgery, Department of Surgery, University of Pittsburgh School of Medicine

1999–2006

  • Research Assistant Professor , Department of Biostatistics, Graduate School of Public Health, University of Pittsburgh

1998–1999

  • Research Instructor in Surgery, Department of Surgery, University of Pittsburgh School of Medicine

1993–1998

  • Project Leader, Section of Computational Medicine, Transplantation Institute, University of Pittsburgh Medical Center

1992–1993

  • PC Consultant, Section of Computational Medicine, Transplantation Institute, University of Pittsburgh Medical Center

1990–1992

  • Radiology Assistant, Radiology Department, University of Pittsburgh Medical Center

1986–1989

  • Senior Research Scientist, Research Institute of Gas Transportation, Kharkov, USSR

1981–1986

  • Senior Engineer, Lecturer, Department of Hydraulics and Power Supply, Ukrainian Polytechnics University Kharkov, USSR

Publications

  • Allen HD, Flanigan KM, Thrush PT, Dvorchik I, Yin H, Canter C, Connolly AM, Parrish M, McDonald CM, Braunlin E, Colan SD, Day J, Darras B, Mendell JR. 2013. A Randomized, Double-Blind Trial of Lisinopril and Losartan for the Treatment of Cardiomyopathy in Duchenne Muscular Dystrophy.  PLOS Currents Muscular Dystrophy. Vol. 1, no. December: 1-13.
  • Nachmany I, Dvorchik I,DeVera M, Fontes P, Demetris A,Humar A, Marsh JW. 2013. A validated model for predicting outcome after liver transplantation: implications on transplanting the extremely sick.  Transplant International. Vol. DOI: 10.1111/tri.12171, no. September: eDOI: 10.1111/tri.12171.
  • Morgan LA, Dvorchik I, Williams KL, Jarrar RG, Buchhalter JR. 2013. Parental ranking of terms describing nonepileptic events.  Pediatric Neurology. Vol. 48, no. 5. (May): 378-382.
  • Boone BA, Zeh HJ, Mock BK, Johnson PJ, Dvorchik I, Lee K, Moser AJ, Bartlett DL, Marsh JW. 2013. Resection of isolated local and metastatic recurrence in periampullary adenocarcinoma.  HPB (Oxford).. Vol. 10.1111/hpb.12119, no. [Epub ahead of print]. (April): e10.1111/hpb.12119. PubMed ID: 23601033
  • Hahn A, Wang W, Jaggi P, Dvorchik I, Ramilo O, Koranyi K, Mejias A. 2013. Human metapneumovirus infections are associated with severe morbidity in hospitalized children of all ages.  Epidemiology And Infection [Epidemiol Infect]. Vol. 1, no. January: 1-11.
  • Jorge I. Arango, Christopher P. Deibert, Danielle Brown, Michael Bell, Igor Dvorchik and P. David Adelson. 2012. Posttraumatic seizures in children with severe traumatic brain injury.  Child's Nervous System: Chns: Official Journal Of The International Society For Pediatric Neurosurgery [Childs Nerv Syst],. Vol. 28, no. 11. (October): 1925-9.
  • Anjali Patwardhan, Robert M. Rennebohm, Igor Dvorchik, Charles H. Spencer. 2012. Is juvenile dermatomyositis a different disease in children up to three years of age at onset than in children above three years at onset? A retrospective review of 23 years of single center experience.  Pediatric Rheumatology Online Journal [Pediatr Rheumatol Online J]. Vol. 10, no. 1. (September): e34.
  • Basu,Amit; Falcone,John; Dvorchik,Igor; Tan,Henkie,P; Schonder,Kristine; Marsh,J,Wallis; Zeevi,Adriana; Humar,Abhinav; Shapiro,Ron. 2011. Outcomes of renal transplantation in recipients with peak panel reactive antibody > 30% under tacrolimus-based immunosuppression.  ANNALS OF TRANSPLANTATION. Vol. 16, no. 3. (July): 5-13.
  • Rosenfeld A, Etzl M, Bandy D, Carpenteri D, Gieseking A, Dvorchik I, Kaplan A. 2011. Use of Positron Emission Tomography in the Evaluation of Diffuse Intrinsic Brainstem Gliomas in Children.  J Pediatr Hematol Oncol. Vol. 33, no. 5. (May): 369-373.
  • Abu-Elmagd,Kareem,M; Mazariegos,George; Costa,Guilherme; Soltys,Kyle; Bond,Geoffrey; Sindhi,Rakesh; Green,Michael; Jaffe,Ronald; Wu,Tong; Koritsky,Darlene; Matarese,Laura; Schuster,Bonnie; Martin,Lillian; Dvorchik,Igor; Nalesnik,Michael,A. 2009. Lymphoproliferative Disorders and De Novo Malignancies in Intestinal and Multivisceral Recipients: Improved Outcomes With New Outlooks.  TRANSPLANTATION. Vol. 88, no. 7. (October): 926-934.
  • Shapiro,Ron; Basu,Amit; Tan,Henkie,P; Morgan,Claire; Sharma,Vivek; Blisard,Deanna; Randhawa,Parmjeet,S; Dvorchik,Igor; McCauley,Jerry; Ellis,Demetrius; Marsh,J,Wallis; Webber,Steven; Kurland,Geoffrey; McCurry,Kenneth,R; Abu-Elmagd,Kareem; Mazariegos,George; Starzl,Thomas,E. 2009. Kidney After Nonrenal Transplantation-The Impact of Alemtuzumab Induction.  TRANSPLANTATION. Vol. 88, no. 6. (September): 799-802.
  • de Vera,M,E; Lopez-Solis,R; Dvorchik,I; Campos,S; Morris,W; Demetris,A,J; Fontes,P; Marsh,J,W. 2009. Liver Transplantation Using Donation After Cardiac Death Donors: Long-Term Follow-Up from a Single Center.  AMERICAN JOURNAL OF TRANSPLANTATION. Vol. 9, no. 4. (April): 773-781.
  • Matarese,Laura,E; Dvorchik,Igor; Costa,Guilherme; Bond,Geoffrey,J; Koritsky,Darlene,A; Ferraris,Ronaldo,P; Touger-Decker,Riva; O'Sullivan-Maillet,Julie,K; Abu-Elmagd,Kareem,M. 2009. Pyridoxal-5 '-phosphate deficiency after intestinal and multivisceral transplantation.  AMERICAN JOURNAL OF CLINICAL NUTRITION. Vol. 89, no. 1. (January): 204-209.
  • Schwartz,Myron; Dvorchik,Igor; Roayaie,Sasan; Fiel,M,Isabel; Finkelstein,Sidney; Marsh,J,Wallis; Martignetti,John,A; Llovet,Josep,M. 2008. Liver transplantation for hepatocellular carcinoma: Extension of indications based on molecular markers.  JOURNAL OF HEPATOLOGY. Vol. 49, no. 4. (October): 581-588.
  • Dvorchik,Igor; Schwartz,Myron; Fiel,M,Isabel; Finkelstein,Sydney,D; Marsh,J,Wallis. 2008. Fractional allelic imbalance could allow for the development of an equitable transplant selection policy for patients with hepatocellular carcinoma.  LIVER TRANSPLANTATION. Vol. 14, no. 4. (April): 443-450.
  • Couto,O,FM; Dvorchik,I; Carr,B,I. 2007. Causes of death in patients with unresectable hepatocellular carcinoma.  DIGESTIVE DISEASES AND SCIENCES. Vol. 52, no. 11. (November): 3285-3289.
  • Dvorchik,Igor; Carr,Brian,I. 2007. A simple prognostic scoring system for patients with unresectable hepatocellular carcinoma treated by chemo-embolization.  CANCER DETECTION AND PREVENTION. Vol. 31, no. 2. (January): 154-160.
  • Dvorchik,I; Demetris,A,J; Geller,D,A; Carr,B,I; Fontes,P; Finkelstein,S,D; Cappella,N,K; Marsh,J,W. 2007. Prognostic models in hepatocellular carcinoma (HCC) and statistical methodologies behind them.  CURRENT PHARMACEUTICAL DESIGN. Vol. 13, no. 15. (January): 1527-1532.
  • Basu,A; Falcone,J,L; Tan,H,P; Hassan,D; Dvorchik,I; Bahri,K; Thai,N; Randhawa,P,S; Marcos,A; Starzl,T,E; Shapiro,R. 2007. Chronic allograft nephropathy score before sirolimus rescue predicts allograft function in renal transplant patients.  TRANSPLANTATION PROCEEDINGS. Vol. 39, no. 1. (January): 94-98.
  • de Vera,M,E; Dvorchik,I; Tom,K; Eghtesad,B; Thai,N; Shakil,O; Marcos,A; Demetris,A; Jain,A; Fung,J,J; Ragni,M,V. 2006. Survival of liver transplant patients coinfected with HIV and HCV is adversely impacted by recurrent hepatitis C.  AMERICAN JOURNAL OF TRANSPLANTATION. Vol. 6, no. 12. (December): 2983-2993.
  • Tan,H,P; Kaczorowski,D,J; Basu,A; Unruh,M; McCauley,J; Wu,C; Donaldson,J; Dvorchik,I; Kayler,L; Marcos,A; Randhawa,P; Smetanka,C; Starzl,T,E; Shapiro,R. 2006. Living donor renal transplantation using alemtuzumab induction and tacrolimus monotherapy.  AMERICAN JOURNAL OF TRANSPLANTATION. Vol. 6, no. 10. (October): 2409-2417.
  • Habib,S; Berk,B; Chang,C,CH; Demetris,A,J; Fontes,P; Dvorchik,I; Eghtesad,B; Marcos,A; Shakil,A,O. 2006. MELD and prediction of post-liver transplantation survival.  LIVER TRANSPLANTATION. Vol. 12, no. 3. (March): 440-447.
  • Geller DA. Tsung A. Marsh JW. Dvorchik I. Gamblin TC. Carr BI. 2006. Outcome of 1000 Liver Cancer Patients Evaluated at the UPMC Liver Cancer Center.  Journal of Gastrointestinal Surgery. Vol. 10, no. 1. (January): 63-68.
  • Ragni,M,V; Eghtesad,B; Schlesinger,K,W; Dvorchik,I; Fung,J,J. 2005. Pretransplant survival is shorter in HIV-positive than HIV-negative subjects with end-stage liver disease.  LIVER TRANSPLANTATION. Vol. 11, no. 11. (November): 1425-1430.
  • Marsh JW. Dvorchik I. 2005. Should we biopsy each liver mass suspicious for hepatocellular carcinoma before liver transplantation?-Yes.  Journal of Hepatology. Vol. 43, no. 4. (October): 558-562.
  • Bonham CA, Goodman M, Finkelstein SD, Dvorchik I, Marsh JW. 2005. Liver transplantation for hepatocellular carcinoma. In Hepatocellular Cancer: Diagnosis and Treatment. Totowa, NJ: Humana Press.
  • Marsh,J,W; Geller,D,A; Finkelstein,S,D; Donaldson,J,B; Dvorchik,I. 2004. Role of liver transplantation for hepatobiliary malignant disorders.  LANCET ONCOLOGY. Vol. 5, no. 8. (August): 480-488.
  • Chopra,K,B; Demetris,A,J; Blakolmer,K; Dvorchik,I; Laskus,T; Wang,L,F; Araya,V,R; Dodson,F; Fung,J,J; Rakela,J; Vargas,H,E. 2003. Progression of liver fibrosis in patients with chronic hepatitis C after orthotopic liver transplantation.  TRANSPLANTATION. Vol. 76, no. 10. (November): 1487-1491.
  • Marsh,J,W; Dvorchik,I. 2003. Liver organ allocation for hepatocellular carcinoma: Are we sure?.  LIVER TRANSPLANTATION. Vol. 9, no. 7. (July): 693-696.
  • Marsh,J,W; Finkelstein,S,D; Demetris,A,J; Swalsky,P,A; Sasatomi,E; Bandos,A; Subotin,M; Dvorchik,I. 2003. Genotyping of hepatocellular carcinoma in liver transplant recipients adds predictive power for determining recurrence-free survival.  LIVER TRANSPLANTATION. Vol. 9, no. 7. (July): 664-671.
  • Finkelstein,S,D; Marsh,W; Demetris,A,J; Swalsky,P,A; Sasatomi,E; Bonham,A; Subotin,M; Dvorchik,I. 2003. Microdissection-based allelotyping discriminates de novo tumor from intrahepatic spread in hepatocellular carcinoma.  HEPATOLOGY. Vol. 37, no. 4. (April): 871-879.
  • Jain,A,B; Eghtesad,B; Venkataramanan,R; Fontes,P,A; Kashyap,R; Dvorchik,I; Shakil,A,O; Kingery,L; Fung,J,J. 2002. Ribavirin dose modification based on renal function is necessary to reduce hemolysis in liver transplant patients with hepatitis C virus infection.  LIVER TRANSPLANTATION. Vol. 8, no. 11. (November): 1007-1013.
  • Demetris,A,J; Ruppert,K; Dvorchik,I; Jain,A; Minervini,M; Nalesnik,M,A; Randhawa,P; Wu,T; Zeevi,A; Abu-Elmagd,K; Eghtesad,B; Fontes,P; Cacciarelli,T; Marsh,W; Geller,D; Fung,J,J. 2002. Real-time monitoring of acute liver-allograft rejection using the Banff schema.  TRANSPLANTATION. Vol. 74, no. 9. (November): 1290-1296.
  • Reyes,J; Mazariegos,G,V; Bond,G,MD; Green,M; Dvorchik,I; Kosmach-Park,B; Abu-Elmagd,K. 2002. Pediatric intestinal transplantation: Historical notes, principles and controversies.  PEDIATRIC TRANSPLANTATION. Vol. 6, no. 3. (June): 193-207.
  • Dvorchik,I; Subotin,M; Demetris,A,J; Fung,J,J; Starzl,T,E; Wieand,S; Abu-Elmagd,K,M. 2002. Effect of liver transplantation on inflammatory bowel disease in patients with primary sclerosing cholangitis.  HEPATOLOGY. Vol. 35, no. 2. (February): 380-384.
  • Joya-Vazquez PP, Dodson FS, Dvorchik I, Gray E, Chesky A, Demetris AJ, Shakil O, Fung JJ, Vargas HE. 2002. Impact of anti-hepatitis BC-positive grafts on the outcome of liver transplantation for HBV- related cirrhosis.  Transplantation. Vol. 73, no. 10. (January): 1598-1602.
  • Ruhul H. Kuddus, Nayema N Kuddus and Dvorchik I. 2002. DNA Polymorphism in the living fossil Ginkgo biloba from the Eastern United States.  Genome. Vol. 45, no. 1. (January): 8-12.
  • Shapiro R, Scantlebury VP, Jordan ML, Vivas CA, Jain A, Hakala TR, McCauley J, Johnston J, Randhawa P, Fedorek S, Gray E, Chesky A, Dvorchik I, Donaldson J, Fung JJ, Starzl TE. 2002. A pilot trial of tacrolimus, sirolimus, and steroids in renal transplant recipients.  Transplantation Proceedings. Vol. 34, no. 5. (January): 1651-1652.
  • Shapiro,R; Randhawa,P; Jordan,M,L; Scantlebury,V,P; Vivas,C; Jain,A; Corry,R,J; McCauley,J; Johnston,J; Donaldson,J; Gray,E,A; Dvorchik,I; Hakala,T,R; Fung,J,J; Starzl,T,E. 2001. An analysis of early renal transplant protocol biopsies - the high incidence of subclinical tubulitis.  AMERICAN JOURNAL OF TRANSPLANTATION. Vol. 1, no. 1. (May): 47-50.
  • Abu-Elmagd K, Reyes J, Bond G, Mazariegos G, Wu T, Murase N, Sindhi R, Martin D, Colangelo J, Zak M, Janson D, Ezzelarab M, Dvorchik I, Parizhskaya M, Deutsch M, Demetris A, Fung J, Starzl TE. 2001. Clinical intestinal transplantation: A decade of experience at a single center.  Annals of Surgery. Vol. 234, no. 3. (January): 404-416.
  • Kirimlioglu H, Dvorchik I, Ruppert K, Finkelstein S, Marsh JW, Iwatsuki S, Bonham A, Carr B, Nalesnik M, Michalopoulos G, Starzl T, Fung J, Demetris A. 2001. Hepatocellular carcinomas in native livers from patients treated with orthotopic liver transplantation: biologic and therapeutic implications.  Hepatology. Vol. 34, no. 3. (January): 502-510.
  • Shapiro R, Rao AS, Corry RJ, Valenti M, Zeevi A, Jordan ML, Scantlebury VP, Vivas CA, Jain A, McCauley J, Randhawa P, Gray EA, Dvorchik I, McMichael J, Fung JJ, Starzl TE. 2001. Kidney transplantation with bone marrow augmentation: five-year outcomes.  Transplantation Proceedings. Vol. 33, no. 1-2. (January): 1134-1135.
  • Fung JJ, Jain A, Kwak EJ, Kusne S, Dvorchik I, Eghtesad B. 2001. De novo malignancies after liver transplantation: a major cause of late death.  Liver Transplantation. Vol. 7, no. 11S. (January): S109-118.
  • Iwatsuki,S; Dvorchik,I; Marsh,J,W; Madariaga,J,R; Carr,B; Fung,J,J; Starzl,T,E. 2000. Liver transplantation for hepatocellular carcinoma: A proposal of a prognostic scoring system.  JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. Vol. 191, no. 4. (October): 389-394.
  • Reyes,J,D; Carr,B; Dvorchik,I; Kocoshis,S; Jaffe,R; Gerber,D; Mazariegos,G,V; Bueno,J; Selby,R. 2000. Liver transplantation and chemotherapy for hepatoblastoma and hepatocellular cancer in childhood and adolescence.  JOURNAL OF PEDIATRICS. Vol. 136, no. 6. (June): 795-804.
  • Carr,B,I; Dvorchik,I. 2000. Effects of cisplatin dose intensity on response and survival for patients with unresectable and untransplantable hepatocellular carcinoma: an analysis of 57 patients.  Gan to kagaku ryoho. Cancer & chemotherapy. Vol. 27, no. May: 432-435.
  • Marsh,J,W; Dvorchik,I; Bonham,C,A; Iwatsuki,S. 2000. Is the pathologic TNM staging system for patients with hepatoma predictive of outcome?.  CANCER. Vol. 88, no. 3. (February): 538-543.
  • Yamamoto,J; Iwatsuki,S; Kosuge,T; Dvorchik,I; Shimada,K; Marsh,J,W; Yamasaki,S; Starzl,T,E. 1999. Should hepatomas be treated with hepatic resection or transplantation?.  CANCER. Vol. 86, no. 7. (October): 1151-1158.
  • Cacciarelli,T,V; Dvorchik,I; Mazariegos,G,V; Gerber,D; Jain,A,B; Fung,J,J; Reyes,J. 1999. An analysis of pretransplantation variables associated with long-term allograft outcome in pediatric liver transplant recipients receiving primary tacrolimus (FK506) therapy.  TRANSPLANTATION. Vol. 68, no. 5. (September): 650-655.
  • Iwatsuki,S; Dvorchik,I; Madariaga,J,R; Marsh,J,W; Dodson,F; Bonham,A,C; Geller,D,A; Gayowski,T,J; Fung,J,J; Starzl,T,E. 1999. Hepatic resection for metastatic colorectal adenocarcinoma: A proposal of a prognostic scoring system.  JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. Vol. 189, no. 3. (September): 291-299.
  • Mazariegos,G,V; O'Toole,K; Mieles,L,A; Dvorchik,I; Meza,M; Briassoulis,G; Arzate,J; Osorio,G; Fung,J,J; Reyes,J. 1999. Hyperbaric oxygen therapy for hepatic artery thrombosis after liver transplantation in children.  LIVER TRANSPLANTATION AND SURGERY. Vol. 5, no. 5. (September): 429-436.
  • Molmenti,E,P; Marsh,J,W; Dvorchik,I; Oliver,J,H; Madariaga,J; Iwatsuki,S. 1999. Hepatobiliary malignancies - Primary hepatic malignant neoplasms.  SURGICAL CLINICS OF NORTH AMERICA. Vol. 79, no. 1. (February): 43-?.
  • Molmenti EP, Marsh JW, Dvorchik I, Oliver III JH, Madariaga J, and Iwatsuki S. 1999. Hepatobiliary Malignancies: Primary Hepatic Malignant Neoplasms. In The Surgical Clinics of North America. Philadelphia, PA: WB Saunders.
  • Daller JA, Bueno J, Gutierrez J, Dvorchik I, Towbin RB, Dickman P, Mazariegos G, Reyes J. Hepatic Hemangioendothelioma: Clinical Experience and Management Strategy. 1999. Hepatic Hemangioendothelioma: Clinical Experience and Management Strategy.  Journal of Pediatric Surgery. Vol. 34, no. 1. (January): 98-105; discussion 105.
  • Molmenti EP, Jain AB, Marino N, Rishi NK, Dvorchik I, and Marsh JW. 1999. Liver Transplantation and Pregnancy. In Clinics in Liver Disease. Philadelphia, PA: WB Saunders.
  • Kapur S. Bonham CA. Dodson SF. Dvorchik I. Corry RJ. 1999. Strategies to expand the donor pool for pancreas transplantation.  Transplantation. Vol. 67, no. 2. (January): 284-290.
  • Corry RJ, Chakrabarti PK, Shapiro R, Rao AS, Dvorchik I, Jordan ML, Scantlebury VP, Vivas CA, Fung JJ, Starzl TE. 1999. Simultaneous Administration of Adjuvant Donor Bone Marrow in Pancreas Transplant Recipients.  Annals of Surgery. Vol. 230, no. 3. (January): 372-381.
  • Bueno J, Ohwada S, Kocoshis S, Mazariegos GV, Dvorchik I, Sigurdsson L, Di Lorenzo C, Abu-Elmagd K, Rayes J. 1999. Factors Impacting on the Survival of Children With Intestinal Failure Referred for Transplantation.  Journal of Pediatric Surgery. Vol. 34, no. 1. (January): 27-34.
  • Bonham CA, Kapur S, Dodson SF, Dvorchik I, Corry RJ. 1999. Potential use of marginal donors for pancreas transplantation.  Transplantation Proceedings. Vol. 31, no. 1-2. (January): 612-613.
  • Achkar,J,P; Araya,V; BARON,R,L; Marsh,J,W; Dvorchik,I; Rakela,J. 1998. Undetected hepatocellular carcinoma: Clinical features and outcome after liver transplantation.  LIVER TRANSPLANTATION AND SURGERY. Vol. 4, no. 6. (November): 477-482.
  • Iwatsuki,S; Todo,S; Marsh,J,W; Madariaga,J,R; Lee,R,G; Dvorchik,I; Fung,J,J; Starzl,T,E. 1998. Treatment of hilar cholangiocarcinoma (Klatskin tumors) with hepatic resection or transplantation.  JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. Vol. 187, no. 4. (October): 358-364.
  • Dvorchik I,.Marsh J.W,.Popechitelev E.P. 1998. Optimization of Feedforward Neural Network Classifier Based on a Concept of Determinate Zone of a Model. In Soft Computing and Measurements
  • Abu-Elmagd,K; Fung,J; Reyes,J; Rao,A; Jain,A; Mazariegos,G; Marsh,W; Madariaga,J; Dvorchik,I; Bueno,J; Rogers,J; McMichael,J; Dodson,F; Vargus,H; Martin,J; Slivka,A; Balan,V; Corry,R; Rakela,J; Murase,N; Demetris,J; Iwatsuki,S; Starzl,T. 1998. Hepatic and intestinal transplantation at the University of Pittsburgh.  Clinical transplants. Vol. 1, no. January: 263-286.
  • Marsh,J,W; Dvorchik,I; Iwatsuki,S. 1998. Liver transplantation in the treatment of hepatocellular carcinoma.  Journal of hepato-biliary-pancreatic surgery. Vol. 5, no. 1. (January): 24-28.
  • Molmenti E, Balan V, Marsh JW, Ishii T, Dvorchik I, Abu-Elmagd K, Minervini M, Demetris AJ, Fung JJ, Rakela J. 1998. Liver Transplantation and Autoimmune Hepatitis Recurrence.  Hepatology. Vol. 28, no. January: e191.
  • Marsh,J,W; Casavilla,A; Iwatsuki,S; Dvorchik,I; Subotin,M; Balan,V; Rakela,J; Subbotin,V; Popechitelev,E,P. 1997. Predicting the risk of tumor recurrence following transplantation for hepatocellular carcinoma.  HEPATOLOGY. Vol. 26, no. 6. (December): 1689-1690.
  • Casavilla,F,A; Marsh,J,W; Iwatsuki,S; Todo,S; Lee,R,G; Madariaga,J,R; Pinna,A; Dvorchik,I; Fung,J,J; Starzl,T,E. 1997. Hepatic resection and transplantation for peripheral cholangiocarcinoma.  JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS. Vol. 185, no. 5. (November): 429-436.
  • Pinna,A,D; Iwatsuki,S; Lee,R,G; Todo,S; Madariaga,J,R; Marsh,J,W; Casavilla,A; Dvorchik,I; Fung,J,J; Starzl,T,E. 1997. Treatment of fibrolamellar hepatoma with subtotal hepatectomy or transplantation.  HEPATOLOGY. Vol. 26, no. 4. (October): 877-883.
  • Marsh,J,W; Dvorchik,I; Subotin,M; Balan,V; Rakela,J; Popechitelev,E,P; Subbotin,V; Casavilla,A; Carr,B,I; Fung,J,J; Iwatsuki,S. 1997. The prediction of risk of recurrence and time to recurrence of hepatocellular carcinoma after orthotopic liver transplantation: A pilot study.  HEPATOLOGY. Vol. 26, no. 2. (August): 444-450.
  • Marsh,J,W; Dvorchik,I; Casavilla,A; Fung,J,J; Iwatsuki,S. 1997. Should reimbursement be denied for liver transplantation in patients with hepatocellular carcinoma?.  JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. Vol. 278, no. 3. (July): 203-205.
  • Dvorchik I. 1997. Interactive Methodology of Data Preprocessing for Neural Network Modeling of Medical Problems (in Russian). Edited by Russian Academy of Sciences. Moscow: Russian Academy of Sciences.
  • Shakil AO, Dvorchik I, Fung JJ, Rakela J. 1997. Liver Transplantation for Acute Liver Failure - Outcome Analysis.  Journal of Viral Hepatitis. Vol. 4, no. S1. (January): 107-110.
  • Madariaga JR, Subbotin VM, Lopez SR, Sahin M, Ferres J, Dvorchik I, Subotin MV, Wang Z, Nalesnik MA, Carr BI, Valdivia LA, Rao AS, Fung JJ. 1997. Quantitative Assessment of the Development of Hepatoma in a Buffalo Rat Model.  Transplantation Proceedings. Vol. 29, no. January: 2263-2264.
  • Marsh JW, Dvorchik I, Subotin M, Ballan V, Rakela J, Popechitelev EP, Subbotin V, Casavilla A, Iwatsuki S. 1997. Predicting the Risk of Tumor Recurrence Following Transplantation for HCC.  Hepatology. Vol. 26, no. 6. (January): 1689-1690.
  • Dvorchik,I; Marsh,W; Gurari,V; Subotin,M; Doyle,H,R. 1996. Multisolutional clustering and quantization algorithm (MCQ).  COMPUTERS IN BIOLOGY AND MEDICINE. Vol. 26, no. 5. (September): 439-450.
  • Ringeride KA, DiMartini A, Marino LJ, Dvorchik I, and Fung JJ. 1996. Health Related Quality of Life (HRQL) in an Adult Orthotopic Liver Transplant (OLT) Population Using the SF-36 Health Survey Questionnaire. In American Society of Transplant Physicians 15th Annual Scientific Meeting
  • Dvorchik,I; Subotin,M; Marsh,W; McMichael,J; Fung,J,J. 1996. Performance of multi-layer feedforward neural networks to predict liver transplantation outcome.  METHODS OF INFORMATION IN MEDICINE. Vol. 35, no. 1. (March): 12-18.
  • Veerabagu M, Balan V, Nelson F, Dvorchik I, Randhawa P, Abu-Elmagd KM, Fung J, Rakela J. 1996. Primary Sclerosing Cholangatis (PSC) and Cholangiocarcinoma: Patient and Graft Survival After Liver Transplantation.  Gastroenterology. Vol. 110, no. 4. (January): e1354.
  • McMichael J, Dvorchik I, Subotin M, Lieberman R. 1995. Improved Training and Performance of Multi-Layer Feedforward Neural Networks Using an Alternative Approach to Data Processing and Missing Data Treatment. In 1994 SCS Western Multiconference, Simulation in the Health Sciences
  • Dvorchik I, Doyle HR, McMichael J. Employing a Novel Clustering and Quantization Algorithm for Data Preprocessing Improves Neural Network Performance. 1994. Employing a Novel Clustering and Quantization Algorithm for Data Preprocessing Improves Neural Network Performance. In World Congress on Computational Medicine, Public Health and Biotechnology
  • Doyle,H,R; Dvorchik,I; Mitchell,S; Marino,I,R; EBERT,F,H; McMichael,J; Fung,J,J. 1994. PREDICTING OUTCOMES AFTER LIVER-TRANSPLANTATION - A CONNECTIONIST APPROACH.  ANNALS OF SURGERY. Vol. 219, no. 4. (April): 408-415.
  • Dvorchik I, Doyle HR. 1994. Improvement of Backpropagation Network's Learning Potentials by Employment of Alternative Clustering and Quantization Data Algorithm. In World Congress on Neural Networks
  • LE Matarese, I Dvorchik, G Costa, GJ Bond, DA Koritsky, RP Ferraris, R Touger-Decker, JK O’Sullivan-Maillet, and K M Abu-Elmagd. Pyridoxal -5’- phosphate deficiency after intestinal and multivisceral transplantation. Am J Clin Nutr . 89(1):204-9, 2009 Jan.
  • I. Dvorchik, M.Schwartz, M.I. Fiel, S.D.Finkelstein, and J.W. Marsh. Fractional Allelic Imbalance Could Allow for the Development of an Equitable Transplant Selection Policy for Patients with Hepatocellular Carcinoma. Liver Transplantation . 14 (4):443-50,2008 Apr.
  • I Dvorchik, AJ Demetris, DA Geller, BI Carr, P.Fontes, SD Finkelstein, NK Cappella and JW Marsh. Prognostic Models in Hepatocellular Carcinoma (HCC) and Statistical Methodologies behind them. Current Pharmaceutical Design, 13(15):1527-32, 2007
  • Dvorchik I. Carr BI. A simple prognostic scoring system for patients with unresectable hepatocellular carcinoma treated by chemo-embolization. Cancer Detection & Prevention. 31(2):154-60, 2007 Apr.
  • Abu-Elmagd KM. Mazariegos G. Costa G. Soltys K. Bond G. Sindhi R. Green M. Jaffe R. Wu T. Koritsky D. Matarese L. Schuster B. Martin L. Dvorchik I. Nalesnik MA. Lymphoproliferative disorders and de novo malignancies in intestinal and multivisceral recipients: improved outcomes with new outlooks. Transplantation. 88(7):926-34, 2009 Oct 15.
  • DeVera ME. Lopez-Solis R. Dvorchik I. Campos S. Morris W. Demetris AJ. Fontes P. Marsh JW. Liver transplantation using donation after cardiac death donors: long-term follow-up from a single center. American Journal of Transplantation. 9(4):773-81, 2009 Apr
  • Schwartz M. Dvorchik I. Roayaie S. Fiel MI. Finkelstein S. Marsh JW. Martignetti JA. Llovet JM. Liver transplantation for hepatocellular carcinoma: extension of indications based on molecular markers. Journal of Hepatology. 49(4):581-8, 2008 Oct.
  • Rosenfeld A, Etzl M, Bandy D, Carpenteri D, Gieseking A, Dvorchik I, Kaplan A. Use of Positron Emission Tomography in the Evaluation of Diffuse Intrinsic Brainstem Gliomas in Children. J Pediatr Hematol Oncol. 2011 Jul;33(5):369-73.
  • Ellis D. Marsh JW. Webber S. Kurland G. McCurry KR. Abu-Elmagd K. Mazariegos G. Starzl TE. Kidney after nonrenal transplantation-the impact of alemtuzumab induction. Transplantation. 88(6):799-802, 2009 Sep 27.
  • Couto OF. Dvorchik I. Carr BI. Causes of death in patients with unresectable hepatocellular carcinoma. Digestive Diseases & Sciences. 52(11):3285-9, 2007 Nov
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