Clifford L. Cua, MD

Clifford Cua, MD, is a Clinical Cardiologist and Cardiac Intensivist at The Heart Center at Nationwide Children's Hospital. He is Assistant Professor of Pediatrics at The Ohio State University College of Medicine. Dr. Cua received his medical degree from Indiana University School of Medicine. After completing his residency, he received fellowship training at Nationwide Children's Hospital and Children’s Hospital Medical Center in Boston. Dr. Cua is certified in Pediatrics.

Gender:

• Male

Languages Spoken:

• English

Medical School

• Indiana University School of Medicine
  Date Completed: 05/11/1997

Internship

• Indiana University School of Medicine
  Date Completed: 06/30/1998

Residency

• Indiana University School of Medicine
  Date Completed: 06/30/2000

Fellowship

• Nationwide Children's Hospital
  Date Completed: 06/30/2003

Fellowship

• Boston Children's Hospital
  Date Completed: 06/30/2004

Department:

• Pediatrics

Section:

• Cardiology

Speciality:

• Pediatric Cardiology
  
• Pediatrics
  

Date of Appointment at Nationwide Children’s Hospital:

• 08/27/2004

• Gokhale J, Husain N, Nicholson L, Texter KM, Zaidi AN, Cua CL. 2013. QRS Duration and Mechanical Dyssynchrony Correlations with Right Ventricular Function after Fontan Procedure.  J Am Soc Echocardiogr. Vol. 26, no. 2. (February): e155 – 160.
• Ozcelik N, Shell R, Holtzlander M, Cua CL. 2013. Decreased Right Ventricular Function in Healthy Pediatric Cystic Fibrosis Patients vs. non-Cystic Fibrosis Patients.  Pediatr Cardiol. Vol. 34, no. 1. (January): e159 – 164.
• Egan MJ, Husain N, Stines JR, Moiduddin M, Stein MA, Nelin LD, Cua CL. 2012. Mid-term Differences in Right Ventricular Function in Patients with Congenital Diaphragmatic Hernia Compared to Controls.  World J Pediatr. Vol. 8, no. 4. (November): e350 – 354.
• Ackerman C, Locke AE, Feingold E, Reshey B, Espana K, Thusberg J, Mooney S, Bean LJH, Dooley KJ, Cua CL, Reeves RH, Sherman SL, Maslen CL. 2012. An Excess of Deleterious Variants in VEGF-A Pathway Genes in Down Syndrome-Associated Atrioventricular Septal Defects.  Am J Hum Genet. Vol. 91, no. 4. (October): e646 – 659.
• Moiduddin N, Texter KM, Cheatham JP, Chisolm JL, Kovalchin JP, Nicholson L, Belfrage KM, Janevski I, Cua CL. 2012. Strain Echocardiographic Assessment of Ventricular Function After Percutaneous Pulmonary Valve Implantation.  Congenit Heart Dis. Vol. 7, no. 4. (July): e361 – 371.
• Phelps C, Thrush P, Cua CL. 2012. The Heart. In Klaus and Fanaroff’s Care of the High-Risk Neonate 6th edition. Edited by Fanaroff JM and Fanaroff AA. Philadelphia: Elsevier.
• Cua CL, FeltesTF. 2012. Echocardiographic evaluation of the single right ventricle in congenital heart disease: results of new techniques.  Circ J. Vol. 76, no. 1. (January): 22-31.
• Fischer AL, Butz C, Nicholson L, Blankenship A, Dyke P, Cua CL. 2012. Caregiver anxiety upon discharge for neonates with congenital heart disease.  Congenit Heart Dis. Vol. 7, no. 1. (January): 41-45.
• Cua CL, Phillips A, Ackley T, Ro PS, Kertesz N. 2011. Optimization of Biventricular Pacing Via Strain Dyssynchrony Measurements in a Pediatric Patient.  Acta Cardiol. Vol. 66, no. 4. (August): 527-530.
• Yates AR, Hoffman TM, Boettner B, Feltes TF, Cua CL. 2011. Initial Counseling Prior to Palliation For Hypoplastic Left Heart Syndrome.  Congenit Heart Dis. Vol. 6, no. 4. (August): 347-358.
• Cua CL, Rogers LK, Chicoine LG, Augustine M, Jin Y, Nash PL, Nelin LD. 2011. Down syndrome patients with pulmonary hypertension have elevated plasma levels of asymmetric dimethylarginine.  Eur J Pediatr. Vol. 170, no. 7. (July): 859-863.
• Stines JR, Hershenson JA, Hayes J, Stefaniak CA, Texter KM, Zaidi AN, Cua CL. 2011. Echocardiographic Assessment of Atrial Properties in Single Ventricles Versus Normal Controls.  Congenit Heart Dis. Vol. 6, no. 3. (May): 247-252.
• Luce WA, Schwartz RM, Beauseau W, Giannone PJ, Boettner BL, Cheatham JP, Galantowicz ME, Cua CL. 2011. Necrotizing enterocolitis in neonates undergoing the hybrid approach to complex congenital heart disease.  Pediatr Crit Care Med. Vol. 12, no. 1. (January): 46-51.
• Locke AE, Dooley KJ, Tinker SW, Cheong SY, Feingold E, Allen EG, Freeman SB, Torfs CP, Cua CL, Epstein MP, Wu MC, Lin X, Capone G, Sherman SL, Bean LJ. 2010. Variation in Folate Pathway Genes Contributes to Risk of Congenital Heart Defects Among Individuals With Down Syndrome.  Genet Epidemiol. Vol. 34, no. 6. (September): 613-623.
• Hershenson JA, Zaidi AN, Texter KM, Moiduddin N, Stefaniak CA, Hayes J, Cua CL. 2010. Differences in Tissue Doppler Imaging Between Single Ventricles After the Fontan Operation and Normal Controls.  Am J Cardiol. Vol. 106, no. 1. (July): 99-103.
• Birnbaum B, Berger GE, Fenstermaker B, Rowland DG, Boettner B, Olshove V, Galantowicz M, Cheatham JP, Cua CL. 2010. Echocardiographic Parameters that Predict Outcome in Aortic Atresia Patients Undergoing Comprehensive Stage II Procedure.  Congenit Heart Dis. Vol. 5, no. 5. (January): 409-415.
• Moiduddin N, Texter KM, Zaidi AN, Hershenson JA, Stefaniak CA, Hayes J, Cua CL. 2010. Two-Dimensional Speckle Strain and Dyssynchrony in Single Left Ventricles Versus Normal Left Ventricles.  Congenit Heart Dis. Vol. 5, no. 6. (January): 579-586.
• Yates AR, Costello JM, Cua CL. 2010. A Review of the Evidence for Glycemic Control in Critically Ill Children. In Intensive Care Units: Stress, Procedure, and Mortality Rates. Edited by LeClaire SE. Hauppauge, NY: Nova Publishers.
• Moiduddin N, Texter KM, Zaidi AN, Hershenson JA, Stefaniak CA, Hayes J, Cua CL. 2010. Two-Dimensional Speckle Strain and Dyssynchrony in Single Right Ventricles Versus Normal Right Ventricles.  J Am Soc Echocardiogr. Vol. 23, no. 6. (January): 673-679.
• Learn CP, Yates AY, Nicholson L, Milton K, Lloyd E, Cua CL. 2010. Tissue Doppler Measurements Correlate with Central Venous Pressure in Pediatric Patients After Cardiac Surgery.  ASAIO J. Vol. 56, no. 4. (January): 377-382.
• Ro PS, Chan DP, Ackley T, Fenstermaker B, Hayes J, Cua CL. 2009. Tissue doppler changes in pediatric complete heart block patients who are chronically paced.  Congenit Heart Dis. Vol. 4, no. 6. (November): 448-453.
• Cua CL, Cooper AL, Stein M, Corbitt R, Nelin LD. 2009. Tissue Doppler changes in three neonates wtih congenital diaphragmatic hernia.  ASAIO. Vol. 55, no. 4. (July): 417-419.
• Cua CL, Chicoine LG, Nelin LD, Mullen M. 2009. Pulmonary Hypertension in the Down Syndrome Population. In Congenital Heart Defects: Etiology, Diagnosis, and Treatment. Edited by Nakamura H. Hauppauge, NY: Nova Publishers.
• Cua CL, Bean LJH, Zender G, Pham T, Sherman SL, Dooley K, McBride KL. 2009. BMPR2 Mutations in the Down Syndrome Population. In Heart Disease in Children. Hauppauge, NY: Nova Publishers.
• Cua CL, Cua CL, Lai L. 2009. Surgical Palliative Options for Patients with Hypoplastic Left Heart. In Congenital Heart Defects: Etiology, Diagnosis, and Treatment. Edited by Nakamura H. Hauppauge, NY: Nova Publishers.
• Fenstermaker B, Berger GE, Rowland DG, Hayes J, Hill SL, Cheatham JP,Galantowicz M, Cua CL. 2008. Interstage echocardiographic changes in patients undergoing hybrid stage I palliation for hypoplastic left heart syndrome.  J Am Soc Echocardiogr. Vol. 21, no. 11. (November): 1222-1228.
• Galantowicz M, Cheatham JP, Phillips A, Cua CL, Hoffman TM, Hill SL, RodemanR. 2008. Hybrid approach for hypoplastic left heart syndrome: intermediate results afterthe learning curve.  Ann Thorac Surg. Vol. 85, no. 6. (June): 2063-2070; discussion 2070.
• Yates AR, Welty SE, Gest AL, Cua CL. 2008. Myocardial tissue Doppler changes in patients with bronchopulmonary dysplasia.  J Pediatr. Vol. 152, no. 6. (January): 766-770.
• Cua CL, Galantowicz ME, Forbes T, Turner D, Hill SL, Hoffman TM, Cheatham JP. 2007. Palliation via hybrid procedure of 1.4 kg patient with a hypoplastic left heart.  Congenit Heart Dis. Vol. 2, no. 3. (May): 191-193.
• Lai L, Laussen PC, Cua CL, Wessel DL, Costello JM, del Nido PJ, Mayer JE, Thiagarajan RR. 2007. Outcomes after bidirectional Glenn operation: Blalock-Taussig shunt versus right ventricle-to-pulmonary artery conduit.  Ann Thorac Surg. Vol. 83, no. 5. (January): 1768-1773.
• Cua CL, A Blankenship, AL North, J Hayes and LD Nelin. 2007. Increased incidence of idiopathic persistent pulmonary hypertension in Down syndrome neonates.  Pediatr Cardiol. Vol. 28, no. January: 250-254.
• Dyke PC 2nd, Yates AR, Cua CL, Hoffman TM, Hayes J, Feltes TF, Springer MA, Taeed R. 2007. Increased calcium supplementation is associated with morbidity and mortality in the infant postoperative cardiac patient.  Pediatr Crit Care Med.. Vol. 8, no. 3. (January): 254-257.
• Cua CL, Cooke G, Taylor M, Hayes J, Waldon L, Lipowski P, Kossman B, Nash PL. 2006. Endothelial nitric oxide synthase polymorphisms associated with abnormal nitric oxide production are not over-represented in children with Down syndrome.  Congenit Heart Dis. Vol. 1, no. 4. (August): 169-174.
• Cua CL, Fenstermaker PB, Dyke PC 2nd. 2006. Changes in tissue Doppler characteristics in a patient with pulmonary atresia and intact ventricular septum.  Cardiol Young. Vol. 16, no. 4. (August): 395-397.
• Cua CL, Thiagarajan RR, Gauvreau K, Lai L, Costello JM, Wessel DL, del Nido P, Mayer Jr JE, Newburger JW, Laussen PC. 2006. Early post-operative outcomes in a series of patients undergoing stage I palliation operation with either modified Blalock-Taussig shunt or right ventricle to pulmonary artery conduit.  Pediatr Crit Care Med. Vol. 7, no. 3. (May): 238-244.
• Yates AR, Dyke PC 2nd, Taeed R, Hoffman TM, Hayes J, Feltes TF, Cua CL. 2006. Hyperglycemia is a marker for poor outcome in the postoperative pediatric cardiac patient.  Pediatr Crit Care Med. Vol. 7, no. 4. (May): 351-355.
• Cua CL, Thiagarajan RR, Taeed R, Hoffman TM, Lai L, Hayes J, Laussen PC, Feltes TF. 2005. Improved interstage mortality with the modified Norwood procedure: a meta-analysis.  Ann Thorac Surg. Vol. 80, no. 1. (July): 44-49.
• Cua CL, Thomas K, Zurakowski D, Laussen PC. 2005. A comparison of the Vasotrac with invasive arterial blood pressure monitoring in children after pediatric cardiac surgery.  Anesth Analg. Vol. 100, no. 5. (May): 1289-1294.
• Cua CL, Sanghavi D, Voss S, Laussen PC, Del Nido P, Marshall A, Breitbart RE. 2004. Right ventricular pseudoaneurysm after modified Norwood procedure.  Ann Thorac Surg. Vol. 78, no. 4. (October): e72-e73.
• Cua CL, Sparks EE, Chan DP, Daniels CJ. 2004. Persistent electrical and morphological atrial abnormalities after early closure of atrial septal defect.  Cardiol Young. Vol. 14, no. 5. (October): 481-487.
• Cua CL, Hoffman TM, Taeed R, Weinstein S, Gomez D, Olshove VF, Craenen JM. 2004. Cerebral saturations trend with mixed venous saturations in patients undergoing extracorporeal life support.  Perfusion. Vol. 19, no. 3. (May): 171-176.
• Weinstein S, Cua C, Chan D, Davis JT. 2003. Outcome of symptomatic patients undergoing extracardiac Fontan conversion and cryoablation.  J Thorac Cardiovasc Surg. Vol. 126, no. 2. (August): 529-536.
• Cua C, Teske D. 2002. Index of Suspicion Case 2: Digoxin Toxicity in a Hypothyroid Down Syndrome Patient.  Pediatr Rev. Vol. 23, no. September: 323-327.
• Backes CH, Cua C, Kreutzer J, Armsby L, El-Said H, Moore JW, Gauvreau K, Bergersen L, Holzer RJ. Low weight as an independent risk factor for adverse events during cardiac catheterization of infants.  Catheter Cardiovasc Interv.
• Zaidi AN, White L, Holt R, Cismowski M, Nicholson L, Cooke SC, Daniels CJ, Cua CL. Correlation of Serum Biomarkers in Adults with Single Ventricles with Strain and Strain Rate using 2-D Speckle Tracking.  Congenit Heart Dis.
• 6. Galantowicz M, Yates AR, Cua CL, Naguib A, Simsic J, Cheatham JP. Peri-operative and Inter-Stage Considerations for the Hybrid Approach for HLHS. In Pediatric and Congenital Cardiology, Cardiac Surgery and Intensive Care. Edited by da Cruz E, Ivy D, Hraska V, and Jaggers J.
• Tsai S, Husain N, Fischer A, Ro PS, Cheatham JP, Galantowicz M, Cua CL. QRS Duration Changes in Patients with Hypoplastic Left Heart Syndrome Undergoing Hybrid Palliation: Pre-Hybrid to Post-Fontan.  Pacing Clin Electrophysiol.
• Miller-Tate H, Stewart J, Allen R, Husain N, Rosen K, Cheatham JP, Galantowicz M, Cua CL. Inter-stage Weight Gain for Patients with Hypoplastic Left Heart Syndrome Undergoing the Hybrid Procedure.  Congenit Heart Dis.
• Cozzi C, Aldrink J, Nicol K, Nicholson L, Cua CL. Intestinal Location of Necrotizing Enterocolitis Among Infants with Congenital Heart Disease.  J Perinatol.
• Cozzi C, Stines J, Luce WA, Hayes J, Cheatham JP, Galantowicz M, Cua CL. Diastolic Flow Parameters are Not Sensitive in Predicting Necrotizing Enterocolitis in Patients Undergoing Hybrid Procedure.  Congenit Heart Dis.
• Cua CL, Galantowicz ME, Turner DR, Forbes TJ, Hill SL, Hoffman TM, Cheatham JP. Palliation via hybrid procedure of 1.4 kg patient with a hypoplastic left heart. Congenital Heart Disease 2: 191-3, 2007.
• Cua C, Galantowicz M, Turner D, Forbes T, Hill SL, Hoffman T, Cheatham JP. Palliation via Hybrid Procedure of a 1.4-kg Patient with a Hypoplastic Left Heart. Congenital Heart Disease: Clinical Studies from Fetus to Adulthood, Vol. 2, No. 3, May-June 2007.
• Dyke PC, Yates AR, Cua CL, Hoffman TM, Hayes J, Feltes TF, Springer MA, Taeed R. Increased calcium supplementation is associated with morbidity and mortality in the infant postoperative cardiac patient. Pediatric Critical Care Medicine 8(3): 254-7, 2007.