Christopher R. Pierson, MD, PhD :: Nationwide Children’s Hospital, Columbus, Ohio

Christopher R. Pierson, MD, PhD

Christopher R. Pierson, MD, PhD

Anatomic Pathology
Pathologist, Neuropathology

Neuro-Oncology
Pathologist, Neuropathology

Pathology and Laboratory Medicine
Anatomic Pathology Team

Pathology Fellowship
Faculty

Contact Information

Laboratory Medicine/Anatomic Pathology
700 Children's Dr
Columbus, OH 43205 [ map ]
PH: (614) 722-5450
FX: (614) 722-2899
Email Me
The Research Institute at Nationwide Children's Hospital
700 Children's Drive
Columbus, Ohio 43205 [ map ]
PH: (614) 355.2723
Business 2: (614) 722.5895

Biography

Christopher R. Pierson, MD, PhD, is a staff pathologist in the Section of Anatomic Pathology in the Department of Laboratory Medicine at Nationwide Children’s Hospital and an Assistant Professor of Pathology at The Ohio State University College of Medicine. Dr. Pierson is certified by the American Board of Pathology in neuropathology and anatomic pathology. He is a principal investigator in the Center for Childhood Cancer within The Research Institute at Nationwide Children’s Hospital. His research is supported by the National Institutes of Health and focuses on pediatric neuromuscular diseases and brain tumors. His clinical interests include perinatal neuropathology and neuromuscular pathology.

View CV »

Gender:

  • Male

Languages Spoken:

  • English

Research Interests

Areas of Interest:

  • Dr. Pierson’s research aims to elucidate the pathogenesis of the centronuclear myopathies, especially X-linked myotubular myopathy, and to develop novel therapies for these myopathies. His expertise and interests in neuropathology include perinatal neuropathology, especially the neuropathology of premature infants, pediatric brain tumors and pediatric neuromuscular diseases.

Education and Training

Medical School

  • Wayne State University School of Medicine
    Date Completed: 06/05/1997

Residency

  • Wayne State University
    Date Completed: 06/30/2002

Fellowship

  • Boston Children's Hospital
    Date Completed: 06/30/2004

Fellowship

  • Harvard - Brigham & Women's Hospital
    Date Completed: 06/30/2004

Department:

  • Pathology & Laboratory Medicine

Section:

  • Anatomic Pathology

Specialty:

  • Anatomic Pathology
  • Neuropathology

Date of Appointment at Nationwide Children’s Hospital:

  • 07/01/2007

Professional Experience

2007–present

  • Assistant Professor in the Department of Pathology at The Ohio State University College of Medicine.

2007–present

  • Neuropathologist, Anatomic Pathology, Nationwide Children's Hospital

Publications

  • 2015. Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas.  NEW ENGLAND JOURNAL OF MEDICINE. Vol. 372, no. 26. (June 25).
  • Pierson CR, Lawlor M. 2015. Other Congenital Myopathies. In Pathobiology of Human Disease: A Dynamic Encylopedia of Disease Mechanisms. Edited by Mitchell R, McManus L.
  • 2015. Complex Brain Malformations Associated with Chromosome 6q27 Gain that Includes THBS2, Which Encodes Thrombospondin 2, an Astrocyte-Derived Protein of the Extracellular Matrix.  PEDIATRIC AND DEVELOPMENTAL PATHOLOGY. Vol. 18, no. 1. (January 1).
  • 2014. SPEG Interacts with Myotubularin, and Its Deficiency Causes Centronuclear Myopathy with Dilated Cardiomyopathy.  AMERICAN JOURNAL OF HUMAN GENETICS. Vol. 95, no. 2. (August 7).
  • Pierson CR, Kahwash S. 2014. Cerebrospinal Fluid and Smear Cytology of the Central Nervous System. In Pediatric Cytopathology: A Practical Guide. Edited by Monaco SE, Teot LA.
  • Lawlor MW, Viola MG, Meng H, Edelstein RV, Liu F, Yan K, Luna EJ, Lerch-Gaggl A, Hoffmann RG, Pierson CR, Buj-Bello A, Lachey JL, Pearsall S, Yang L, Hillard CJ, Beggs AH. 2014. Differential muscle hypertrophy is associated with satellite cell numbers and Akt pathway activation following activin type IIB receptor inhibition in Mtm1 p.R69C Mice.  AMERICAN JOURNAL OF PATHOLOGY. Vol. 184, no. 6. (June): 1831-1842.
  • Lawlor MW, Viola MG, Meng H, Edelstein RV, Liu F, Yan K, Luna E, Lerch-Gaggl A, Hoffmann R, Pierson CR, Buj-Bello A, Lachey JL, Pearsall S, Yang L, Hillard C, Beggs AH. 2014. Differential Muscle Hypertrophy Is Associated With Satellite Cell Numbers And Akt Pathway Activation Following Activin Type IIB Receptor Inhibition Of Mtm1 p.R69C Mice.  Am J Pathol. Vol. 184, no. 6. (June 1): 1831-42-1831-42.
  • 2014. Differential Muscle Hypertrophy Is Associated with Satellite Cell Numbers and Akt Pathway Activation Following Activin Type IIB Receptor Inhibition in Mtm1 p.R69C Mice.  AMERICAN JOURNAL OF PATHOLOGY. Vol. 184, no. 6. (June 1).
  • Marlin ES, Entwistle JJ, Arnold MA, Pierson CR, Governale LS. 2014. Thoracolumbar spinal vascular malformation as a rare cause of isolated intraventricular hemorrhage.  J Neurosurg Pediatr. Vol. May 2, no. May 1: Epub ahead of print-Epub ahead of print.
  • 2014. Treatment of medulloblastoma with oncolytic measles viruses expressing the angiogenesis inhibitors endostatin and angiostatin.  BMC CANCER. Vol. 14, no. March 19.
  • Hutzen B, Bid HK, Houghton PJ, Pierson CR, Powell K, Bratasz A, Raffel C, Studebaker AW. 2014. Treatment of medulloblastoma with oncolytic measles virus expressing the angiogenesis inhibitors endostatin and angiostatin.  BMC Cancer. Vol. 14, no. 1. (March 1): 206-206.
  • Dorris K, Sobo M, Onar-Thomas A, Panditharatna E, Stevenson CB, Gardner SL, DeWire MD, Pierson CR, Olshefski R, Rempel SA, Goldman S, Miles L, Fouladi M, Drissi R. 2014. Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas.  JOURNAL OF NEURO-ONCOLOGY. Vol. 117, no. 1. (March): 67-76.
  • Dorris K, Sobo M, Onar-Thomas A, Panditharatna E, Stevenson CB, Gardner SL, Dewire MD, Pierson CR, Olshefski R, Rempel SA, Goldman S, Miles L, Fouladi M, Drissi R. 2014. Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas.  J Neurooncol. Vol. 117, no. March: 67-76.
  • Hutzen B, Bid HK, Houghton PJ, Pierson CR, Powell K, Bratasz A, Raffel C, Studebaker AW. 2014. Treatment of medulloblastoma with oncolytic measles viruses expressing the angiogenesis inhibitors endostatin and angiostatin.  BMC CANCER. Vol. 14, no. March: e206.
  • Brownstein CA, Beggs AH, Homer N, there are 199 co-authors on this paper Pierson CR is author number 107. 2014. An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.  Genome Biol. Vol. 15, no. 3. (March): eR53.
  • Dorris K, Sobo M, Onar-Thomas A, Panditharatna E, Stevenson CB, Gardner SL, DeWire MD, Pierson CR, Olshefski R, Rempel SA, Goldman S, Miles L, Fouladi M, Drissi R. 2014. Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas.  JOURNAL OF NEURO-ONCOLOGY. Vol. 117, no. 1. (March 1): 67-76-67-76.
  • Brownstein CA, Beggs AH, Homer N, there are 199 co-authors on this paper Pierson CR is author number 107. 2014. An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.  Genome Biol. Vol. 15, no. 3. (March 1): R53-R53.
  • Dorris K, Sobo M, Onar-Thomas A, Panditharatna E, Stevenson CB, Gardner SL, Dewire MD, Pierson CR, Olshefski R, Rempel SA, Goldman S, Miles L, Fouladi M, Drissi R. 2014. Prognostic significance of telomere maintenance mechanisms in pediatric high-grade gliomas.  J Neurooncol. Vol. 117, no. March 1: 67-76-67-76.
  • Kaur S, Powell S, He L, Pierson CR, Parikh NA. 2014. Reliability and repeatability of quantitative tractography methods for mapping structural white matter connectivity in preterm and term infants at term-equivalent age.  PLOS ONE. Vol. 9, no. 1. (January): ee85807.
  • Graff A, Haines KM, Bolon B, Pierson CR, Heyob KM, Houston RH, Velten M, Collins LR, Rogers LK. 2014. Oligodendrocyte Injury Persists into Adulthood in a Mouse Model of Systemic Maternal Inflammation and Neonatal Hyperoxia.  Life Sciences. Vol. 92, no. January 1: 164-171-164-171.
  • Graf AE, Haines KM, Pierson CR, Bolon BN, Houston RH, Velten M, Heyob KM, Rogers LK. 2014. Perinatal inflammation results in decreased oligodendrocyte numbers in adulthood.  LIFE SCIENCES. Vol. 94, no. 2. (January 1): 164-171-164-171.
  • Kaur S, Powell S, He L, Pierson CR, Parikh NA. 2014. Reliability and Repeatability of Quantitative Tractography Methods for Mapping Structural White Matter Connectivity in Preterm and Term Infants at Term-Equivalent Age.  PLos ONE. Vol. 9, no. January 1: e85807-e85807.
  • Kaur S, Powell S, He L, Pierson CR, Parikh NA. 2014. Reliability and repeatability of quantitative tractography methods for mapping structural white matter connectivity in preterm and term infants at term-equivalent age.  PLOS ONE. Vol. 9, no. 1. (January 1): e85807-e85807.
  • Graf AE, Haines KM, Pierson CR, Bolon BN, Houston RH, Velten M, Heyob KM, Rogers LK. 2014. Perinatal inflammation results in decreased oligodendrocyte numbers in adulthood.  LIFE SCIENCES. Vol. 94, no. 2. (January): 164-171.
  • 2013. Phase II study of cilengitide in the treatment of refractory or relapsed high-grade gliomas in children: A report from the Children's Oncology Group.  NEURO-ONCOLOGY. Vol. 15, no. 10. (October 1).
  • Haines KM, Wang W, Pierson CR. 2013. Cerebellar hemorrhagic injury in premature infants occurs during a vulnerable developmental period and is associated with wider neuropathology.  ACTA NEUROPATHOLOGICA COMMUNICATIONS. Vol. 1, no. 1. (October): e69.
  • Haines KM, Wang W, Pierson CR. 2013. Cerebellar Hemorrhagic Injury in Premature Infants Occurs During a Vulnerable Developmental Period and is Associated with Wider Neuropathology.  Acta Neuropathol Comm. Vol. 1, no. 69. (October 1): 1-14-1-14.
  • MacDonald TJ, Vezina G, Stewart CF, Turner D, Pierson CR, Chen L, Pollack IF, Gajjar A, Kieran MW. 2013. Phase II study of cilengitide in the treatment of refractory or relapsed high-grade gliomas in children: A report from the Children's Oncology Group.  NEURO-ONCOLOGY. Vol. 15, no. 10. (October): 1438-1444.
  • MacDonald TJ, Vezina G, Stewart CF, Turner D, Pierson CR, Chen L, Pollack IF, Gajjar A, Kieran MW. 2013. Phase II study of cliengitide in the treatment of refactory or relapsed high-grade gliomas in children: A report from the Children's Oncology Group.  Neuro-onocology. Vol. 15, no. September 1: 1438-1444-1438-1444.
  • Snyder AD, Dulin-Smith AN, Houston RH, Durban AN, Brisbin BJ, Oostra TD, Marshall JT, Kahwash BM, Pierson CR. 2013. Expression Pattern of Id Proteins in Medulloblastoma.  Pathology Oncology Research. Vol. 19, no. July: 437-446.
  • 2013. Expression Pattern of Id Proteins in Medulloblastoma.  PATHOLOGY & ONCOLOGY RESEARCH. Vol. 19, no. 3. (July 1).
  • Arnold,Michael,A; Stallings-Archer,Kandi; Marlin,Evan; Grondin,Ronald; Olshefski,Randal; Biegel,Jaclyn,A; Pierson,Christopher,R. 2013. Cribriform Neuroepithelial Tumor Arising in the Lateral Ventricle.  PEDIATRIC AND DEVELOPMENTAL PATHOLOGY. Vol. 16, no. 4. (July): 301-307.
  • Snyder AD, Dulin-Smith AN, Houston RH, Durban AN, Brisbin BJ, Oostra TD, Marshall JT, Kahwash BM, Pierson CR. 2013. Expression Pattern of Id Proteins in Medulloblastoma.  Pathology Oncology Research. Vol. 19, no. July 1: 437-446-437-446.
  • Snyder AD, Dulin-Smith AN, Houston RH, Durban AN, Brisbin BJ, Oostra TD, Marshall JT, Kahwash BM, Pierson CR. 2013. Expression pattern of Id proteins in medulloblastoma.  PATHOLOGY & ONCOLOGY RESEARCH. Vol. 19, no. 3. (July): 437-446.
  • Arnold,Michael,A; Stallings-Archer,Kandi; Marlin,Evan; Grondin,Ronald; Olshefski,Randal; Biegel,Jaclyn,A; Pierson,Christopher,R. 2013. Cribriform Neuroepithelial Tumor Arising in the Lateral Ventricle.  PEDIATRIC AND DEVELOPMENTAL PATHOLOGY. Vol. 16, no. 4. (July 1): 301-307-301-307.
  • 2013. Enzyme replacement therapy rescues weakness and improves muscle pathology in mice with X-linked myotubular myopathy.  HUMAN MOLECULAR GENETICS. Vol. 22, no. 8. (April 15).
  • Arnold MA,Stallings-Archer K, Marlin E,Grondin R, Olshefski R, Biegel JA, Pierson CR. 2013. Cribriform Neuroepithelial Tumor Arising in the Lateral Ventricle.  Pediatric and Developmental Pathology. Vol. 16, no. March: 301-307.
  • Arnold MA,Stallings-Archer K, Marlin E,Grondin R, Olshefski R, Biegel JA, Pierson CR. 2013. Cribriform Neuroepithelial Tumor Arising in the Lateral Ventricle.  Pediatric and Developmental Pathology. Vol. 16, no. March 1: 301-307-301-307.
  • 2013. Cerebellar hemorrhagic injury in premature infants occurs during a vulnerable developmental period and is associated with wider neuropathology.  Acta neuropathologica communications. Vol. 1, no. 1. (January 1).
  • 2012. Treatment of medulloblastoma using an oncolytic measles virus encoding the thyroidal sodium iodide symporter shows enhanced efficacy with radioiodine.  BMC CANCER. Vol. 12, no. November 7.
  • Hutzen,Brian; Pierson,Christopher,R; Russell,Stephen,J; Galanis,Evanthia; Raffel,Corey; Studebaker,Adam,W. 2012. Treatment of medulloblastoma using an oncolytic measles virus encoding the thyroidal sodium iodide symporter shows enhanced efficacy with radioiodine.  BMC CANCER. Vol. 12, no. November: e508.
  • 2012. Myotubular myopathy and the neuromuscular junction: a novel therapeutic approach from mouse models.  DISEASE MODELS & MECHANISMS. Vol. 5, no. 6. (November 1).
  • Dowling,James,J; Joubert,Romain; Low,Sean,E; Durban,Ashley,N; Messaddeq,Nadia; Li,Xingli; Dulin-Smith,Ashley,N; Snyder,Andrew,D; Marshall,Morgan,L; Marshall,Jordan,T; Beggs,Alan,H; Buj-Bello,Anna; Pierson,Christopher,R. 2012. Myotubular myopathy and the neuromuscular junction: a novel therapeutic approach from mouse models.  DISEASE MODELS & MECHANISMS. Vol. 5, no. 6. (November): 852-859.
  • Cajaiba,Mariana,M; Hughes,Anna,MS; Pierson,Christopher,R. 2012. Central nervous system pathology in an infant with short-chain acyl-CoA dehydrogenase deficiency (SCADD): evidence for abnormal neuronal migration as part of its phenotypic spectrum.  CLINICAL NEUROPATHOLOGY. Vol. 31, no. 5. (September): 386-388.
  • 2012. Central nervous system pathology in an infant with short-chain acyl-CoA dehydrogenase deficiency (SCADD): evidence for abnormal neuronal migration as part of its phenotypic spectrum.  CLINICAL NEUROPATHOLOGY. Vol. 31, no. 5. (September 1).
  • Boehm J, Biancalana V, DeChene ET, Bitoun M, Pierson CR, Schaefer E, Karasoy H, Dempsey MA, Klein F, Dondaine N, Kretz C, Haumesser N, Poirson C, Toussaint A, Greenleaf RS, Barger MA, Mahoney LJ, Kang PB, Zanoteli E, Vissing J, Witting N, Echaniz-Laguna A, Wallgren-Pettersson C, Dowling J, Merlini L, Oldfors A, Ousager LB, Melki J, Krause A, Jern C, Oliveira ASB, Petit F, Jacquette A, Chaussenot A, Mowat D, Leheup B, Cristofano M, Poza Aldea JJ, Michel F, Furby A, Barcena Llona JE, Van Coster R, Bertini E, Urtizberea JA, Drouin-Garraud V, Beroud C, Prudhon B, Bedford M, Mathews K, Erby LAH, Smith SA, Roggenbuck J, Crowe CA, Spitale AB, Johal SC, Amato AA, Demmer LA, Jonas J, Darras BT, Bird TD, Laurino M, Welt SI, Trotter C, Guicheney P, Das S, Mandel JL, Beggs AH, Laporte J. 2012. Mutation Spectrum in the Large GTPase Dynamin 2, and Genotype-Phenotype Correlation in Autosomal Dominant Centronuclear Myopathy.  HUMAN MUTATION. Vol. 33, no. 6. (June 1): 949-959-949-959.
  • Boehm,Johann; Biancalana,Valerie; DeChene,Elizabeth,T; Bitoun,Marc; Pierson,Christopher,R; Schaefer,Elise; Karasoy,Hatice; Dempsey,Melissa,A; Klein,Fabrice; Dondaine,Nicolas; Kretz,Christine; Haumesser,Nicolas; Poirson,Claire; Toussaint,Anne; Greenleaf,Rebecca,S; Barger,Melissa,A; Mahoney,Lane,J; Kang,Peter,B; Zanoteli,Edmar; Vissing,John; Witting,Nanna; Echaniz-Laguna,Andoni; Wallgren-Pettersson,Carina; Dowling,James; Merlini,Luciano; Oldfors,Anders; Ousager,Lilian,Bomme; Melki,Judith; Krause,Amanda; Jern,Christina; Oliveira,Acary,SB; Petit,Florence; Jacquette,Aurelia; Chaussenot,Annabelle; Mowat,David; Leheup,Bruno; Cristofano,Michele; Poza Aldea,Juan,Jose; Michel,Fabrice; Furby,Alain; Barcena Llona,Jose,E; Van Coster,Rudy; Bertini,Enrico; Urtizberea,Jon,Andoni; Drouin-Garraud,Valerie; Beroud,Christophe; Prudhon,Bernard; Bedford,Melanie; Mathews,Katherine; Erby,Lori,AH; Smith,Stephen,A; Roggenbuck,Jennifer; Crowe,Carol,A; Spitale,Allison,Brennan; Johal,Sheila,C; Amato,Anthony,A; Demmer,Laurie,A; Jonas,Jessica; Darras,Basil,T; Bird,Thomas,D; Laurino,Mercy; Welt,Selman,I; Trotter,Cynthia; Guicheney,Pascale; Das,Soma; Mandel,Jean-Louis; Beggs,Alan,H; Laporte,Jocelyn. 2012. Mutation Spectrum in the Large GTPase Dynamin 2, and Genotype-Phenotype Correlation in Autosomal Dominant Centronuclear Myopathy.  HUMAN MUTATION. Vol. 33, no. 6. (June): 949-959.
  • Böhm,Johann; Biancalana,Valérie; DeChene,Elizabeth,T; Bitoun,Marc; Pierson,Christopher,R; Schaefer,Elise; Karasoy,Hatice; Dempsey,Melissa,A; Klein,Fabrice; Dondaine,Nicolas; Kretz,Christine; Haumesser,Nicolas; Poirson,Claire; Toussaint,Anne; Greenleaf,Rebecca,S; Barger,Melissa,A; Mahoney,Lane,J; Kang,Peter,B; Zanoteli,Edmar; Vissing,John; Witting,Nanna; Echaniz-Laguna,Andoni; Wallgren-Pettersson,Carina; Dowling,James; Merlini,Luciano; Oldfors,Anders; Bomme Ousager,Lilian; Melki,Judith; Krause,Amanda; Jern,Christina; Oliveira,Acary,SB; Petit,Florence; Jacquette,Aurélia; Chaussenot,Annabelle; Mowat,David; Leheup,Bruno; Cristofano,Michele; Poza Aldea,Juan,José; Michel,Fabrice; Furby,Alain; Llona,Jose,EBarcena; Van Coster,Rudy; Bertini,Enrico; Urtizberea,Jon,Andoni; Drouin-Garraud,Valérie; Béroud,Christophe; Prudhon,Bernard; Bedford,Melanie; Mathews,Katherine; Erby,Lori,AH; Smith,Stephen,A; Roggenbuck,Jennifer; Crowe,Carol,A; Brennan Spitale,Allison; Johal,Sheila,C; Amato,Anthony,A; Demmer,Laurie,A; Jonas,Jessica; Darras,Basil,T; Bird,Thomas,D; Laurino,Mercy; Welt,Selman,I; Trotter,Cynthia; Guicheney,Pascale; Das,Soma; Mandel,Jean-Louis; Beggs,Alan,H; Laporte,Jocelyn. 2012. Mutation spectrum in the large GTPase dynamin 2, and genotype-phenotype correlation in autosomal dominant centronuclear myopathy.  Human mutation. Vol. 33, no. 6. (June 1): 949-959-949-959.
  • Böhm,Johann; Biancalana,Valérie; DeChene,Elizabeth,T; Bitoun,Marc; Pierson,Christopher,R; Schaefer,Elise; Karasoy,Hatice; Dempsey,Melissa,A; Klein,Fabrice; Dondaine,Nicolas; Kretz,Christine; Haumesser,Nicolas; Poirson,Claire; Toussaint,Anne; Greenleaf,Rebecca,S; Barger,Melissa,A; Mahoney,Lane,J; Kang,Peter,B; Zanoteli,Edmar; Vissing,John; Witting,Nanna; Echaniz-Laguna,Andoni; Wallgren-Pettersson,Carina; Dowling,James; Merlini,Luciano; Oldfors,Anders; Bomme Ousager,Lilian; Melki,Judith; Krause,Amanda; Jern,Christina; Oliveira,Acary,SB; Petit,Florence; Jacquette,Aurélia; Chaussenot,Annabelle; Mowat,David; Leheup,Bruno; Cristofano,Michele; Poza Aldea,Juan,José; Michel,Fabrice; Furby,Alain; Llona,Jose,EBarcena; Van Coster,Rudy; Bertini,Enrico; Urtizberea,Jon,Andoni; Drouin-Garraud,Valérie; Béroud,Christophe; Prudhon,Bernard; Bedford,Melanie; Mathews,Katherine; Erby,Lori,AH; Smith,Stephen,A; Roggenbuck,Jennifer; Crowe,Carol,A; Brennan Spitale,Allison; Johal,Sheila,C; Amato,Anthony,A; Demmer,Laurie,A; Jonas,Jessica; Darras,Basil,T; Bird,Thomas,D; Laurino,Mercy; Welt,Selman,I; Trotter,Cynthia; Guicheney,Pascale; Das,Soma; Mandel,Jean-Louis; Beggs,Alan,H; Laporte,Jocelyn. 2012. Mutation spectrum in the large GTPase dynamin 2, and genotype-phenotype correlation in autosomal dominant centronuclear myopathy.  Human mutation. Vol. 33, no. 6. (June): 949-959.
  • 2012. Oncolytic measles virus prolongs survival in a murine model of cerebral spinal fluid-disseminated medulloblastoma.  NEURO-ONCOLOGY. Vol. 14, no. 4. (April 1).
  • 2012. Modeling the human MTM1 p.R69C mutation in murine Mtm1 results in exon 4 skipping and a less severe myotubular myopathy phenotype.  HUMAN MOLECULAR GENETICS. Vol. 21, no. 4. (February 15).
  • 2011. Modeling the Human C205T Mutation in Murine Mtm1 Results in Exon 4 Skipping and a Less Severe Myotubular Myopathy Phenotype.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 70, no. 6. (June 1).
  • Pierson,Christopher; Rusin,Jerome. 2011. Deep White Matter Venous Infarction in Infants: A Neuroradiologic-Neuropathologic Correlation.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 70, no. 6. (June): 515-515.
  • Pierson C, Rusin J. 2011. Deep White Matter Venous Infarction in Infants: A Neuroradiologic-Neuropathologic Correlation.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 70, no. 6. (June 1): 515-515-515-515.
  • Pierson,Christopher; Dulin-Smith,Ashley; Durban,Ashley; Marshall,Jordan; Snyder,Andrew; Gladman,Jordan; Chandler,Dawn; Buj-Bello,Anna; Lawlor,Michael; Dowling,James; Beggs,Alan. 2011. Modeling the Human C205T Mutation in Murine Mtm1 Results in Exon 4 Skipping and a Less Severe Myotubular Myopathy Phenotype.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 70, no. 6. (June): 524-524.
  • Lawlor MW, Read BP, Edelstein R, Yang N, Pierson CR, Stein MJ, Wermer-Colan A, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH. 2011. Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin deficient mice.  Am J Pathol. Vol. 2, no. 178. (February 1): 784-793-784-793.
  • 2010. Treatment of medulloblastoma with a modified measles virus.  NEURO-ONCOLOGY. Vol. 12, no. 10. (October 1).
  • Smith,Krista; Boesel,Carl; Hughes,Anna; Pierson,Christopher. 2010. Cerebellar Hemorrhagic Injury in Premature Infants and its Associated Neuropathology: A Clinicopathologic Study of 18 Cases.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 69, no. 5. (May): 545-545.
  • Smith K, Boesel C, Hughes A, Pierson C. 2010. Cerebellar Hemorrhagic Injury in Premature Infants and its Associated Neuropathology: A Clinicopathologic Study of 18 Cases.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 69, no. 5. (May 1): 545-545-545-545.
  • Pierson C, Snyder A, Houston R, Marshall J, Kahwash B, Dulin-Smith A. 2010. Id Proteins are Differentially Expressed in Medulloblastoma Tumor Cells and Endothelia.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 69, no. 5. (May 1): 544-544-544-544.
  • Pierson,Christopher; Snyder,Andrew; Houston,Ronald; Marshall,Jordan; Kahwash,Basil; Dulin-Smith,Ashley. 2010. Id Proteins are Differentially Expressed in Medulloblastoma Tumor Cells and Endothelia.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 69, no. 5. (May): 544-544.
  • Pierson,Christopher; Dulin-Smith,Ashley; Roth,Kristen; Marshall,Morgan; Naiyer,Nada; Marshall,Jordan; Snyder,Andrew; Gladman,Jordan; Chandler,Dawn; Beggs,Alan. 2010. The Mtm1C205T Knock-In Mouse: A New Model of Myotubular Myopathy With a Mild Phenotype.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 69, no. 5. (May): 548-548.
  • 2010. Id Proteins are Differentially Expressed in Medulloblastoma Tumor Cells and Endothelia.
  • 2010. The Mtm1C205T Knock-In Mouse: A New Model of Myotubular Myopathy With a Mild Phenotype.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 69, no. 5. (May 1).
  • Dowling JJ, Pierson C, Buj-Bello A, Feldman EL. 2010. Neuromuscular Junction Abnormalities and Myotubular Myopathy.  ANNALS OF NEUROLOGY. Vol. 68, no. 4. (January 1): S22-S22-S22-S22.
  • 2009. Neuronal loss in Pelizaeus-Merzbacher disease differs in various mutations of the proteolipid protein 1.  ACTA NEUROPATHOLOGICA. Vol. 118, no. 4. (October 1).
  • 2008. AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis.  HUMAN MOLECULAR GENETICS. Vol. 17, no. 14. (July 15).
  • 2007. Gray matter injury associated with periventricular leukomalacia in the premature infant.  ACTA NEUROPATHOLOGICA. Vol. 114, no. 6. (December 1).
  • 2007. Myofiber size correlates with MTM1 mutation type and outcome in X-linked myotubular myopathy.  NEUROMUSCULAR DISORDERS. Vol. 17, no. 7. (July 1).
  • 2006. Is the late preterm infant more vulnerable to gray matter injury than the term infant?.  CLINICS IN PERINATOLOGY. Vol. 33, no. 4. (December 1).
  • 2006. Case 35-2006: A newborn boy with hypotonia.  New England Journal of Medicine. Vol. 355, no. 20. (November 16).
  • Gorson KC, Adelman LS, Pierson CR, Beggs AH. 2006. Sporadic, adult-onset nemaline myopathy presenting as camptocormia (Bent-Spine Syndrome).  J Clin Neuromusc Dis. Vol. 8, no. 1. (September 1): 7-11-7-11.
  • 2005. X-linked myotubular and centronuclear myopathies.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 64, no. 7. (July 1).
  • Pierson CR, Tomczak K, Agrawal P, Moghadaszadeh B, Beggs AH. 2005. Please update record with Title.  J Neuropathol Exp Neurol. Vol. 64, no. 7. (July 1): 555-564-555-564.
  • Christopher R. Pierson. 2004. Proinsulin C-peptide Deficiency Partially Accounts for the Differences in Peripheral Nerve Regeneration Between Type 1- and Type 2- Diabetic Neuropathies.: Wayne State University.
  • 2004. Molecular alterations underlie nodal and paranodal degeneration in type 1 diabetic neuropathy and are prevented by C-peptide.  DIABETES. Vol. 53, no. 6. (June 1).
  • Pierson,C; Darras,B; Xin,W; De Girolami,U. 2004. Late infantile neuronal ceroid lipofuscinosis due to heterozygous CLN2 mutations including a novel T3915G point mutation in one allele.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 63, no. 5. (May): 534-534.
  • Pierson,C,R; Ligon,K,L; Goumnerova,L,C; Richkind,K; De Girolami,U. 2004. Primary meningeal sarcomatosis (PMS): A case report with cytogenetic findings and a review of the literature.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 63, no. 5. (May): 544-544.
  • 2004. Molecular alterations underlie nodal degeneration in type 1 diabetic neuropathy and are prevented by C-peptide.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 63, no. 5. (May 1).
  • 2004. Primary meningeal sarcomatosis (PMS): A case report with cytogenetic findings and a review of the literature.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 63, no. 5. (May 1).
  • Sima,A,AF; Zhang,W; Pierson,C,R. 2004. Molecular alterations underlie nodal degeneration in type 1 diabetic neuropathy and are prevented by C-peptide.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 63, no. 5. (May): 515-515.
  • Pierson C, Darras B, Xin W, De Girolami U. 2004. Late infantile neuronal ceroid lipofuscinosis due to heterozygous CLN2 mutations including a novel T3915G point mutation in one allele.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 63, no. 5. (May 1): 534-534-534-534.
  • 2003. Proinsulin C-peptide replacement in type 1 diabetic BB/Wor-rats prevents deficits in nerve fiber regeneration.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 62, no. 7. (July 1).
  • Pierson,C,R; Folkerth,R,D; Haynes,R,L; Drinkwater,M,E; Volpe,J,J; Kinney,H,C. 2003. Gray matter injury in premature infants with or without periventricular leukomalacia (PVL).  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 62, no. 5. (May): 578-578.
  • 2003. Pathogenesis of colloid (pure mucinous) carcinoma of exocrine organs - Coupling of gel-forming mucin (MUC2) production with altered cell polarity and abnormal cell-stroma interaction may be the key factor in the morphogenesis and indolent behavior of colloid carcinoma in the breast and pancreas.  AMERICAN JOURNAL OF SURGICAL PATHOLOGY. Vol. 27, no. 5. (May 1).
  • 2003. Gray matter injury in premature infants with or without periventricular leukomalacia (PVL).  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 62, no. 5. (May 1).
  • 2003. Insulin deficiency rather than hyperglycemia accounts for impaired neurotrophic responses and nerve fiber regeneration in type 1 diabetic neuropathy.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 62, no. 3. (March 1).
  • Pierson CR, Sima A. 2003. Metabolic Alterations in Experimental Models of Diabetic Neuropathy. In Diabetic Neuropathy. Edited by FA Gries, NE Cameron, PA Low, D Ziegler.
  • 2002. Maspin is up-regulated in premalignant prostate epithelia.  PROSTATE. Vol. 53, no. 4. (December 1).
  • 2002. Impaired glucose tolerance and insulinopenia in the GK-rat causes peripheral neuropathy.  DIABETES-METABOLISM RESEARCH AND REVIEWS. Vol. 18, no. 6. (November 1).
  • 2002. Early gene responses of trophic factors in nerve regeneration differ in experimental type 1 and type 2 diabetic polyneuropathies.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 61, no. 10. (October 1).
  • Pierson,C,R; Garbern,J; Golden,J,A; Kupsky,W; Sima,A,A. 2002. Neuronal system degeneration in Pelizaeus-Merzbacher disease with PLP1 gene duplication.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 61, no. 5. (May): 450-450.
  • 2002. Neuronal system degeneration in Pelizaeus-Merzbacher disease with PLP1 gene duplication.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 61, no. 5. (May 1).
  • 2002. Altered tubulin and neurofilament expression and impaired axonal growth in diabetic nerve regeneration.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 61, no. 2. (February 1).
  • 2001. Human C-peptide dose dependently prevents early neuropathy in the BB/Wor-rat.  International Journal of Experimental Diabetes Research. Vol. 2, no. 3. (December 27).
  • 2001. Diabetic neuropathy: a heterogeneous, dynamic, and progressive disorder.  JOURNAL OF NEUROSCIENCE RESEARCH. Vol. 66, no. 6. (December 15).
  • 2001. Mixed epithelial and stromal tumor of the kidney lacks the genetic alterations of cellular congenital mesoblastic nephroma.  HUMAN PATHOLOGY. Vol. 32, no. 5. (May 1).
  • Adsay NV, Pierson CR, Sarkar F, Abrams J, Weaver D, Conlon KC, Brennan MF, Klimstra DS. 2001. Colloid (mucinous noncystic) carcinoma of the pancreas.  Am J Surg Pathol. Vol. 25, no. 1. (January 1): 26-42-26-42.
  • Adsay NV, Pierson C, Sarkar F, Abrams J, Weaver D, Conlon K, Brennan MF, Klimstra DS. 2001. Colloid (mucinous noncystic) carcinoma of the pancreas.  AMERICAN JOURNAL OF SURGICAL PATHOLOGY. Vol. 25, no. 1. (January 1): 26-42-26-42.
  • Adsay NV, Cheng J, Pierson CR, Klimstra DS. 2001. Colloid carcinoma of the pancreas.  Case Rev Surg Pathol. Vol. 6, no. January 1: 115-120-115-120.
  • Sima AA, Sugimoto K, Zhang WX, Pierson C, Murakawa Y. 2000. Nodal and paranodal structural and molecular changes in type 1 diabetic neuropathy are preventable by C-peptide.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 59, no. 5. (May 1): 456-456-456-456.
  • Sima AA, Sugimoto K, Zhang WX, Pierson C, Murakawa Y. 2000. Nodal and paranodal structural and molecular changes in type 1 diabetic neuropathy are preventable by C-peptide.  JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY. Vol. 59, no. 5. (May): 456-456.
  • Gugnani MK, Pierson CR, Vander Heide R, Girgis RE. 2000. Pulmonary edema complicating prostacyclin therapy in pulmonary hypertension associated with scleroderma: a case of pulmonary capillary hemangiomatosis.  Arthritis Rheum. Vol. 43, no. 3. (March 1): 699-703-699-703.
  • Pierson CR, Sakr W, Sarkar F, Pontes JE, Crissman J, Grignon DJ. 2000. Retinoblastoma gene expression as a prognostic indicator in invasive bladder cancer.  J Urologic Pathol. Vol. 12, no. January 1: 1-12-1-12.
  • 1999. Pelizaeus-Merzbacher disease.
  • Pierson CR, Nassar H, Sakr W, Banerjee R, Grignon DJ. 1999. Primary malignant fibrous histiocytoma of the urinary bladder: a case report and review of the literature.  J Urologic Pathol. Vol. 11, no. 2. (January 1): 195-205-195-205.
  • Nie D, Hillman GG, Geddes T, Tang K, Pierson CR, Grignon DJ, Honn KV. 1999. Platelet-type 12-lipoxygenase regulates angiogenesis in human prostate carcinoma.  Adv Exp Med Biol. Vol. 469, no. January 1: 623-630-623-630.
  • Nie D, Hillman GG, Geddes T, Tang K, Pierson CR, Grignon DJ, Honn KV. 1998. Platelet-type 12-lipoxygenase in a human prostate carcinoma stimulates angiogenesis and tumor growth.  Cancer Res. Vol. 58, no. 18. (September 1): 4047-4051-4047-4051.
  • 1970. The Muscular Dystrophy Association of Canada.  Canadian journal of public health = Revue canadienne de sante publique. Vol. 61, no. 5. (September 1).
  • Snyder AD, Dulin-Smith AN, Houston RH, Durban AN, Brisbin BJ, Oostra TD, Marshall JT, Kahwash BM, Pierson CR. Expression of Id Proteins in Medulloblastoma.  Pathology Oncology Research.
  • Arnold M, Stallings-Archer K, Marlin E, Grondin R, Olshefski R, Biegel JA, Pierson CR. Cribriform Neuroepithelial Tumor Arising in the Lateral Ventricle.  Pediatric Developmental Pathology.
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