Chack-Yung Yu, D.Phil. :: Nationwide Children's Hospital, Columbus, Ohio

Chack-Yung Yu, D.Phil.

Chack-Yung  Yu, D.Phil.

Contact Information

The Research Institute at Nationwide Children's Hospital
700 Children's Drive
Columbus, Ohio 43205 [ map ]
PH: (614) 722.2821
FX: (614) 722.2817
E-mail Me

Biography

View CV »

Gender:

  • Male

Languages Spoken:

  • English

Research Interests

Research Center:

Areas of Interest:

  • Currently we are investigating the details of gene copy number variations in human autoimmune, neurological and infectious diseases. We are funded by the NIH to study the genetic and clinical risk factors of human systemic lupus erythematosus (SLE). We are a member of the Ohio SLE Study Group that consists of four research teams headed by Dr. Lee Hebert, Dr. Brad Rovin, Dr. Dan Birmingham and Dr. Chack-Yung Yu. Our laboratory is specialized in molecular genetic analyses of human complex diseases. Our lab is recognized for the characterization of the RCCX modules and gene copy number variations of human complement components C4A and C4B. We apply a variety of genotyping and phenotyping techniques in our research projects, which include real-time PCR, genomic restriction fragment length polymorphism, DNA sequencing, pulsed field gel electrophoresis, immunofixation, immunodiffusion and flow cytometry.

Education and Training

Undergraduate School

  • The Chinese University of Hong Kong
    Date Completed: 06/30/1981

Master's

  • The Chinese University of Hong Kong
    Date Completed: 06/30/1983

Doctorate

  • Trinity College, Oxford University
    Date Completed: 01/31/1987

Fellowship

  • MRC Laboratory of Molecular Biology
    Date Completed: 01/31/1989

Professional Experience

2006–present

  • Professor, Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University

1991–present

  • Faculty Member, Molecular, Cellular and Development Biology Program, The Ohio State University

1990–present

  • Principal Investigator, The Research Institute at Nationwide Children's Hospital 

1996–2006

  • Associate Professor, Department of Pediatrics, Department of Molecular Virology, Immunology and Medical Genetics, The Ohio State University

1990–1996

  • Assistant Professor, Pediatrics, Medical Microbiology and Immunology, The Ohio State University

1987–1990

  • Research Fellow and Non-Clinical Scientific Staff, MRC Laboratory of Molecular Biology, Cambridge,U.K. (with Dr. Cesar Milstein, Nobel laureate, C.H., F.R.S.)

1983–1987

  • Research Student, Medical Research Council (MRC) Immunochemistry Unit, Oxford University (with the late Prof. Rodney R. Porter, Nobel laureate, C.H., F.R.S. and Dr. R. Duncan Campbell)

Publications

  • Sakurai D, Zhao J, Deng Y, Kelly JA, Brown EE, Harley JB, Bae SC, Alarc?n-Riquelme ME; BIOLUPUS and GENLES networks, Edberg JC, Kimberly RP, Ramsey-Goldman R, Petri MA, Reveille JD, Vilá LM, Alarcón GS, Kaufman KM, Vyse TJ, Jacob CO, Gaffney PM, Sivils KM, James JA, Kamen DL, Gilkeson GS, Niewold TB, Merrill JT, Scofield RH, Criswell LA, Stevens AM, Boackle SA, Kim JH, Choi J, Pons-Estel BA; Argentine Collaborative Group, Freedman BI, Anaya JM, Martin J, Yu CY, Chang DM, Song YW, Langefeld CD, Chen W, Grossman JM, Cantor RM, Hahn BH, Tsao BP. 2013. Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.  PLoS Genet. 2013;9(10):e1003870. doi: 10.1371/journal.pgen.1003870. Epub 2013 Oct 10.. Vol. 9, no. 10. (October): ee1003870.
  • Kaufman,Kenneth,M; Zhao,Jian; Kelly,Jennifer,A; Hughes,Travis; Adler,Adam; Sanchez,Elena; Ojwang,Joshua,O; Langefeld,Carl,D; Ziegler,Julie,T; Williams,Adrienne,H; Comeau,Mary,E; Marion,Miranda,C; Glenn,Stuart,B; Cantor,Rita,M; Grossman,Jennifer,M; Hahn,Bevra,H; Song,Yeong,Wook; Yu,Chack-Yung; James,Judith,A; Guthridge,Joel,M; Brown,Elizabeth,E; Alarcon,Graciela,S; Kimberly,Robert,P; Edberg,Jeffrey,C; Ramsey-Goldman,Rosalind; Petri,Michelle,A; Reveille,John,D; Vila,Luis,M; Anaya,Juan-Manuel; Boackle,Susan,A; Stevens,Anne,M; Freedman,Barry,I; Criswell,Lindsey,A; Pons-Estel,Bernardo,A; Lee,Joo-Hyun; Lee,Ji-Seon; Chang,Deh-Ming; Scofield,R,Hal A; Gilkeson,Gary,S; Merrill,Joan,T; Niewold,Timothy,B; Vyse,Timothy,James; Bae,Sang-Cheol; Alarcon-Riquelme,Marta,E; Jacob,Chaim,O; Sivils,Kathy,Moser; Gaffney,Patrick,M; Harley,John,B; Sawalha,Amr,H; Tsao,Betty,P. 2013. Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.  ANNALS OF THE RHEUMATIC DISEASES. Vol. 72, no. 3. (March): 437-444.
  • Mueller,Michael; Barros,Paula; Witherden,Abigail,S; Roberts,Amy,L; zhang,zhou; Schaschl,Helmut; Yu,Chack-Yung; Hurles,Matthew,E; Schaffner,Catherine; Floto,R,Andres; Game,Laurence; Steinberg,Karyn,Meltz; Wilson,Richard,K; Graves,Tina,A; Eichler,Evan,E; Cook,H,Terence; Vyse,Timothy,J; Aitman,Timothy,J. 2013. Genomic Pathology of SLE-Associated Copy-Number Variation at the FCGR2C/FCGR3B/FCGR2B Locus.  AMERICAN JOURNAL OF HUMAN GENETICS. Vol. 92, no. 1. (January): 28-40.
  • Kaiser,Rachel; Taylor,Kimberly,E; Deng,Yun; Zhao,Jian; Li,Yonghong; Nititham,Joanne; Chang,Monica; Catanese,Joseph; Begovich,Ann,B; Brown,Elizabeth,E; Edberg,Jeffrey,C; McGwin,Gerald; Alarcon,Graciela,S; Ramsey-Goldman,Rosalind; Reveille,John,D; Vila,Luis,M; Petri,Michelle; Kimberly,Robert,P; Feng,Xuebing; Sun,Lingyun; Shen,Nan; Li,Wei; Lu,Jian-Xin; Wakeland,Edward,K; Li,Quan-Zhen; Yang,Wanling; Lau,Yu-Lung; Liu,Fei-Lan; Chang,Deh-Ming; Yu,Chack-Yung; Song,Yeong,W; Howe,Hwee,Siew; Tsao,Betty,P; Criswell,Lindsey,A. 2013. Brief Report: Single-nucleotide polymorphisms in VKORC1 are risk factors for systemic lupus erythematosus in Asians.  ARTHRITIS AND RHEUMATISM. Vol. 65, no. 1. (January): 211-215.
  • Kingery SE, Wu YL, Zhou B, Hoffman RP, Yu CY. 2012. Complement C4A and C4B as novel biomarkers for partial disease remissions in new onset type 1 diabetes.  Pediatric Diabetes. Vol. 13, no. 5. (August): 408-418.
  • Birmingham DJ, Hebert LA, Song H, Noonan WT, Rovin BH, Nagaraja HN, Yu CY. 2012. Evidence that abnormally large seasonal declines in vitamin D status may trigger SLE flare in non-African Americans.  Lupus. Vol. 21, no. 8. (July): 855-864.
  • Rigby WFC, Wu YL, Zan M, Rosengren S, Carlson C, Hilton W, Yu CY. 2012. Increased frequency of C4B deficiency in rheumatoid arthritis.  Arthritis Rheum. Vol. 64, no. 5. (May): 1338-1344.
  • Lessard,Christopher,J; Adrianto,Indra; Ice,John,A; Wiley,Graham,B; Kelly,Jennifer,A; Glenn,Stuart,B; Adler,Adam,J; Li,He; Rasmussen,Astrid; Williams,Adrienne,H; Ziegler,Julie; Comeau,Mary,E; Marion,Miranda; Wakeland,Benjamin,E; Liang,Chaoying; Ramos,Paula,S; Grundahl,Kiely,M; Gallant,Caroline,J; Alarcon-Riquelme,Marta,E; Alarcon,Graciela,S; Anaya,Juan-Manuel; Bae,Sang-Cheol; Boackle,Susan,A; Brown,Elizabeth,E; Chang,Deh-Ming; Cho,Soo-Kyung; Criswell,Lindsey,A; Edberg,Jeffrey,C; Freedman,Barry,I; Gilkeson,Gary,S; Jacob,Chaim,O; James,Judith,A; Kamen,Diane,L; Kimberly,Robert,P; Kim,Jae-Hoon; Martin,Javier; Merrill,Joan,T; Niewold,Timothy,B; Park,So-Yeon; Petri,Michelle,A; Pons-Estel,Bernardo,A; Ramsey-Goldman,Rosalind; Reveille,John,D; Scofield,R,Hal; Song,Yeong,Wook; Stevens,Anne,M; Tsao,Betty,P; Vila,Luis,M; Vyse,Timothy,J; Yu,Chack-Yung; Guthridge,Joel,M; Kaufman,Kenneth,M; Harley,John,B; Wakeland,Edward,K; Langefeld,Carl,D; Gaffney,Patrick,M; Montgomery,Courtney,G; Moser,Kathy,L. 2012. Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as Susceptibility Loci for Systemic Lupus Erythematosus in a Large-Scale Multiracial Replication Study.  AMERICAN JOURNAL OF HUMAN GENETICS. Vol. 90, no. 4. (April): 648-660.
  • Rigby,William,FC; Wu,Y,L; Zan,Moe,T; Zhou,Bi; Rosengren,Sanna; Carlson,Cheryl; Hilton,Whitney; Jones,Jonathan,D; Yu,Chack-Yung. 2011. Increased Frequency of Complement C4B Deficiency in Rheumatoid Arthritis (RA): Interaction with the Shared Epitope (SE). In 75th Annual Scientific Meeting of the American-College-of-Rheumatology/46th Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals (ARHP)
  • Sakurai,Daisuke; Zhao,Jian; Deng,Yun; Kaufman,Kenneth; Kelly,Jennifer,A; Kimberly,Robert,P; Alarcon-Riquelme,Marta,E; Harley,John,B; Bae,Sang-Cheol; Jacob,Chaim,O; Vyse,Timothy,J; Niewold,Timothy,B; Gaffney,Patrick,M; Moser,Kathy,L; James,Judith,A; Gilkeson,Gary,S; Kamen,Diane,L; Langefeld,Carl,D; Chang,Deh-Ming; Song,Yeong,Wook; Yu,Chack-Yung; Grossman,Jennifer,M; Cantor,Rita,M; Hahn,Bevra,H; Tsao,Betty,P. 2011. Risk Alleles of SLE Associated IL10 SNPs Conferred Differential Binding to Transcription Factors. In 75th Annual Scientific Meeting of the American-College-of-Rheumatology/46th Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals (ARHP)
  • Deng,Yun; Grossman,Jennifer,M; Fu,Qiong; Martin,William; Quirk,Matthew; Rullo,Ornella,J; Boackle,Susan,A; Putterman,Chaim; Salmon,Jane,E; Kyttaris,Vasileios,C; Tsokos,George,C; Magdangal,Erika; Sahakian,Lori; Chen,Weiling; Woo,Jennifer,MP; McCurdy,Deborah,K; Yu,Chack-Yung; Hahn,Bevra,H; McMahon,Maureen,A; Tsao,Betty,P. 2011. Association of Androgen Receptor Gene Polymorphism with Damage in Systemic Lupus Erythematosus. In 75th Annual Scientific Meeting of the American-College-of-Rheumatology/46th Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals (ARHP)
  • Rutherford,A; Zhou,B; Wu,Y,L; Kingery,S,E; Germak,J; Bowden,S; Hoffman,R,P; Yu,C,Y. 2011. ANALYSIS OF THE HUMAN AMYLASE LOCUS REVEALED EXTENSIVE COPY NUMBER VARIATION OF SALIVARY AND PANCREATIC AMYLASE GENES IN TYPE 1 DIABETES PATIENTS. In 52nd Annual Scientific Meeting of the Midwest-Society-for-Pediatric-Research
  • Wu,Y,L; Brookshire,B,P; Verani,R,R; Arnett,F,C; Yu,C,Y. 2011. Clinical presentations and molecular basis of complement C1r deficiency in a male African-American patient with systemic lupus erythematosus.  LUPUS. Vol. 20, no. 11. (October): 1126-1134.
  • Tan,Wenfeng; Sunahori,Katsue; Zhao,Jian; Deng,Yun; Kaufman,Kenneth,M; Kelly,Jennifer,A; Langefeld,Carl,D; Williams,Adrienne,H; Comeau,Mary,E; Ziegler,Julie,T; Marion,Miranda,C; Bae,Sang-Cheol; Lee,Joo,Hyun; Lee,Ji-Seon; Chang,Deh-Ming; Song,Yeong,Wook; Yu,Chack-Yung; Kimberly,Robert,P; Edberg,Jeffrey,C; Brown,Elizabeth,E; Petri,Michelle,A; Ramsey-Goldman,Rosalind; Vila,Luis,M; Reveille,John,D; Alarcon-Riquelme,Marta,E; Harley,John,B; Boackle,Susan,A; Stevens,Anne,M; Scofield,R,Hal; Merrill,Joan,T; Freedman,Barry,I; Anaya,Juan-Manuel; Criswell,Lindsey,A; Jacob,Chaim,O; Vyse,Timothy,J; Niewold,Timothy,B; Gaffney,Patrick,M; Moser,Kathy,L; Gilkeson,Gary,S; Kamen,Diane,L; James,Judith,A; Grossman,Jennifer,M; Hahn,Bevra,H; Tsokos,George,C; Tsao,Betty,P. 2011. Association of PPP2CA Polymorphisms With Systemic Lupus Erythematosus Susceptibility in Multiple Ethnic Groups.  ARTHRITIS AND RHEUMATISM. Vol. 63, no. 9. (September): 2755-2763.
  • Ardoin,Stacy; Birmingham,Daniel,J; Hebert,Paul,L; Yu,Chack-Yung; Rovin,Brad,H; Hebert,Lee,A. 2011. An Approach to Validating Criteria for Proteinuric Flare in Systemic Lupus Erythematosus Glomerulonephritis.  ARTHRITIS AND RHEUMATISM. Vol. 63, no. 7. (July): 2031-2037.
  • Zhao,Jian; Wu,Hui; Khosravi,Melanie; Cui,Huijuan; Qian,Xiaoxia; Kelly,Jennifer,A; Kaufman,Kenneth,M; Langefeld,Carl,D; Williams,Adrienne,H; Comeau,Mary,E; Ziegler,Julie,T; Marion,Miranda,C; Adler,Adam; Glenn,Stuart,B; Alarcon-Riquelme,Marta,E; Pons-Estel,Bernardo,A; Harley,John,B; Bae,Sang-Cheol; Bang,So-Young; Cho,Soo-Kyung; Jacob,Chaim,O; Vyse,Timothy,J; Niewold,Timothy,B; Gaffney,Patrick,M; Moser,Kathy,L; Kimberly,Robert,P; Edberg,Jeffrey,C; Brown,Elizabeth,E; Alarcon,Graciela,S; Petri,Michelle,A; Ramsey-Goldman,Rosalind; Vila,Luis,M; Reveille,John,D; James,Judith,A; Gilkeson,Gary,S; Kamen,Diane,L; Freedman,Barry,I; Anaya,Juan-Manuel; Merrill,Joan,T; Criswell,Lindsey,A; Scofield,R,Hal; Stevens,Anne,M; Guthridge,Joel,M; Chang,Deh-Ming; Song,Yeong,Wook; Park,Ji,Ah; Lee,Eun,Young; Boackle,Susan,A; Grossman,Jennifer,M; Hahn,Bevra,H; Goodship,Timothy,HJ; Cantor,Rita,M; Yu,Chack-Yung; Shen,Nan; Tsao,Betty,P. 2011. Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility.  PLOS GENETICS. Vol. 7, no. 5. (May): ee1002079.
  • Fu,Qiong; Zhao,Jian; Qian,Xiaoxia; Wong,Jonathan,LH; Kaufman,Kenneth,M; Yu,C,Yung; Howe,Hwee,Siew; Mok,Mo,Yin; Harley,John,B; Guthridge,Joel,M; Song,Yeong,Wook; Cho,Soo-Kyung; Bae,Sang-Cheol; Grossman,Jennifer,M; Hahn,Bevra,H; Arnett,Frank,C; Shen,Nan; Tsao,Betty,P. 2011. Association of a Functional IRF7 Variant With Systemic Lupus Erythematosus.  ARTHRITIS AND RHEUMATISM. Vol. 63, no. 3. (March): 749-754.
  • Lessard,Christopher,J; Adrianto,Indra; Kelly,Jennifer,A; Kaufman,Kenneth,M; Grundahl,Kiely,M; Adler,Adam; Williams,Adrienne,H; Gallant,Caroline,J; Alarcon-Riquelme,Marta,E; Anaya,Juan-Manuel; Bae,Sang-Cheol; Boackle,Susan,A; Brown,Elizabeth,E; Chang,Deh-Ming; Criswell,Lindsey,A; Edberg,Jeffrey,C; Freedman,Barry,I; Gregersen,Peter,K; Gilkeson,Gary,S; Jacob,Chaim,O; James,Judith,A; Kamen,Diane,L; Kimberly,Robert,P; Martin,Javier; Merrill,Joan,T; Niewold,Timothy,B; Park,So-Yeon; Petri,Michelle,A; Pons-Estel,Bernardo,A; Ramsey-Goldman,Rosalind; Reveille,John,D; Song,Yeong,Wook; Stevens,Anne,M; Tsao,Betty,P; Vila,Luis,M; Vyse,Timothy,J; Yu,Chack-Yung; Guthridge,Joel,M; Bruner,Gail,R; Langefeld,Carl,D; Montgomery,Courtney; Harley,John,B; Scofield,R,Hal; Gaffney,Patrick,M; Moser,Kathy,L. 2011. Identification of a Systemic Lupus Erythematosus Susceptibility Locus at 11p13 between PDHX and CD44 in a Multiethnic Study.  AMERICAN JOURNAL OF HUMAN GENETICS. Vol. 88, no. 1. (January): 83-91.
  • Atkinson, J.P. and Yu, C.Y. 2011. Genetic Susceptibility and Class III complement Genes. In Systemic Lupus Erythematosus. Fifth ed. Edited by Lahita,R.G., Tsokos,G., Buyon,J., Koike,T.. Amsterdam: Academic Press at Elsevier.
  • Birmingham,D,J; Irshaid,F; Nagaraja,H,N; Zou,X; Tsao,B,P; Wu,H; Yu,C,Y; Hebert,L,A; Rovin,B,H. 2010. The complex nature of serum C3 and C4 as biomarkers of lupus renal flare.  LUPUS. Vol. 19, no. 11. (October): 1272-1280.
  • Soto,K; Wu,Y,L; Ortiz,A; Aparicio,S,R; Yu,C,Y. 2010. Familial C4B deficiency and immune complex glomerulonephritis.  CLINICAL IMMUNOLOGY. Vol. 137, no. 1. (October): 166-175.
  • Shen,Nan; Fu,Qiong; Deng,Yun; Qian,Xiaoxia; Zhao,Jian; Kaufman,Kenneth,M; Wu,Yee,Ling; Yu,C,Yung; Tang,Yuanjia; Chen,Ji-Yih; Yang,Wanling; Wong,Maida; Kawasaki,Aya; Tsuchiya,Naoyuki; Sumida,Takayuki; Kawaguchi,Yasushi; Howe,Hwee,Siew; Mok,Mo,Yin; Bang,So-Young; Liu,Fei-Lan; Chang,Deh-Ming; Takasaki,Yoshinari; Hashimoto,Hiroshi; Harley,John,B; Guthridge,Joel,M; Grossman,Jennifer,M; Cantor,Rita,M; Song,Yeong,Wook; Bae,Sang-Cheol; Chen,shunle; Hahn,Bevra,H; Lau,Yu,Lung; Tsao,Betty,P. 2010. Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus.  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Vol. 107, no. 36. (September): 15838-15843.
  • Wu,Yee,Ling; Lundstrom,Emeli; Liu,Chau-Ching; Yang,Yan; Gunnarsson,Iva; Svenungsson,Elisabet; Zhou,Bi; Jones,Karla,N; Nagaraja,Haikady,N; Higgins,Gloria,C; Spencer,Charles; Brunner,Hermine; Birmingham,Dan,J; Rovin,Brad,H; Tsao,Betty,P; Ahearn,Joseph,M; Hebert,Lee,A; Padyukov,Leonid; Yu,C,Yung. 2010. Low gene copy-number of complement C4A, the presence of HLA-DR3, and the presence of HLA-DR2 are independent and additive risk factors for human systemic lupus erythematosus. In 23rd International National Complement Workshop
  • Wu,Yee,Ling; Brookshire,Blake; Yu,Chack-Yung; Arnett,Frank. 2010. Molecular basis of complement C1r deficiency in a male African American patient with systemic lupus erythematosus. In 23rd International National Complement Workshop
  • Bitter,Joshua; Dials,Sarah; Nagaraja,Haikady,N; Yu,C,Yung; Rovin,Brad,H; Hebert,Lee,A; Birmingham,Daniel,J. 2010. Changes in anti-C1q IgG levels neither forecast nor mark a lupus nephritis flare. In 23rd International National Complement Workshop
  • Fernando,Michelle,MA; Boteva,Lora; Morris,David,L; Zhou,Bi; Wu,Yee,Ling; Lokki,Marja-Liisa; Yu,Chack,Yung; Rioux,John,D; Hollox,Edward,J; Vyse,Timothy,J. 2010. Assessment of Complement C4 Gene Copy Number Using the Paralog Ratio Test.  HUMAN MUTATION. Vol. 31, no. 7. (July): 866-874.
  • Kingery,S,E; Hoffman,R,P; Wu,Y,L; Yu,C,Y. 2010. Higher Complement C4 Protein Levels Are Positively Correlated with beta-Cell Preservation in New Onset Type 1 Diabetes Mellitus. In 92nd Meeting and Expo of the Endocrine Society (ENDO 2010)
  • Kingery,Suzanne,E; Wu,Yee-Ling; Zhou,Bi; Hoffman,Robert,P; Yu,C,Yung. 2009. LOWER COMPLEMENT C4 GENE COPY NUMBER IS A GENETIC RISK FACTOR FOR TYPE 1 DIABETES MELLITUS IN PEDIATRIC PATIENTS. In 50th Annual Scientific Meeting of the Midwest-Society-for-Pediatric-Research
  • Wu,Y,L; Hauptmann,G; Viguier,M; Yu,C,Y. 2009. Molecular basis of complete complement C4 deficiency in two North-African families with systemic lupus erythematosus.  GENES AND IMMUNITY. Vol. 10, no. 5. (July): 433-445.
  • Kingery,Suzanne,E; Wu,Yee-Ling; Yang,Zhenyu; Chung,Erwin,K; Zipf,William; Germak,John,A; Hoffman,Robert,P; Yu,C,Yung. 2009. Monomodular RP-C4-CYP21-TNX (RCCX) Haplotype with a Short Gene for Complement Component C4B Is a Genetic Risk Factor for Type 1 Diabetes Mellitus (T1D) with the Age of Onset Modified by C4A Copy Number Variation. In 69th Annual Meeting of the American-Diabetes-Association
  • Saxena,Kapil; Kitzmiller,Kathryn,J; Wu,Yee,Ling; Zhou,Bi; Esack,Nazreen; Hiremath,Leena; Chung,Erwin,K; Yang,Yan; Yu,C,Yung. 2009. Great genotypic and phenotypic diversities associated with copy-number variations of complement C4 and RP-C4-CYP21-TNX (RCCX) modules: A comparison of Asian-Indian and European American populations.  MOLECULAR IMMUNOLOGY. Vol. 46, no. 7. (April): 1289-1303.
  • Hebert,Lee,A; Birmingham,Daniel,J; Shidham,Ganesh; Rovin,Brad; Nagaraja,H,N; Yu,Chack-Yung. 2009. Random Spot Urine Protein/Creatinine Ratio Is Unreliable for Estimating 24-Hour Proteinuria in Individual Systemic Lupus Erythematosus Nephritis Patients.  NEPHRON CLINICAL PRACTICE. Vol. 113, no. 3. (January): C177-C182.
  • Carvalho Santos,Pablo,Sandro; Fuest,George; Prohaszka,Zoltan; Volz,Armin; Horton,Roger; Miretti,Marcos; Yu,Chack-Yung; Beck,Stephan; Uchanska-Ziegler,Barbara; Ziegler,Andreas. 2008. Association of Smoking Behavior with an Odorant Receptor Allele Telomeric to the Human Major Histocompatibility Complex.  GENETIC TESTING. Vol. 12, no. 4. (December): 481-486.
  • Wu,Haifeng; Birmingham,Daniel,J; Rovin,Brad; Hackshaw,Kevin,V; Haddad,Nabil; Haden,Douglas; Yu,Chack-Yung; Hebert,Lee,A. 2008. D-Dimer Level and the Risk for Thrombosis in Systemic Lupus Erythematosus.  CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. Vol. 3, no. 6. (November): 1628-1636.
  • Wu,Yee,Ling; Chung,Erwin; Yang,Yan; Zhou,Bi; Nagaraja,Haikady,N; Birmingham,Dan; Rovin,Brad; Hebert,Lee; Gilkeson,Gary; Lau,Yu-Lung; Lau,Chak-Sing; Yu,C,Yung. 2008. Low gene copy of complement C4 is a common genetic risk factor for human systemic lupus erythematosus in three different racial groups. In 22nd International Complement Workshop
  • Kitzmiller,Kathryn; Roubey,Robert,AS; Savelli,Stephanie,L; Nagaraja,Haikady,N; Hebert,Lee,A; Yu,C,Yung. 2008. Decreased functional MBL is a risk factor for venous thrombosis in human subjects with antiphospholipid antibodies. In 22nd International Complement Workshop
  • Zhang,Xiaolan; Jin,Ming; Wu,Haifeng; Nadasdy,Tibor; Nadasdy,Gyongyi; Harris,Nathan; Green-Church,Kari; Nagaraja,Haikady; Birmingham,Daniel,J; Yu,Chack-Yung; Hebert,Lee,A; Rovin,Brad,H. 2008. Biomarkers of lupus nephritis determined by serial urine proteomics. In 40th Annual Meeting of the American-Society-of-Nephrology/Annual Renal Week
  • Zhang X; Jin M; Wu H; Nadasdy T; Nadasdy G; Harris N; Green-Church K; Nagaraja H; Birmingham DJ; Yu CY; Hebert LA; Rovin BH. 2008. Biomarkers of lupus nephritis determined by serial urine proteomics.  Kidney International. Vol. 74, no. 6. (September): e799.
  • Savelli,Stephanie,L; Roubey,Robert,AS; Wu,Yee,Ling; Yang,Yan; Kitzmiller,Kathryn,J; Nagaraja,Haikady,N; Hebert,Lee,A; Yu,Chack-Yung. 2008. Contrasting roles of complement C4 and C3 in human antiphospholipid syndrome (APS) and systemic lupus erythernatosus (SLE). In 72nd Annual Scientific Meeting of the American-College-of-Rheumatology/43rd Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals
  • Wu,Hui; Qian,Xiaoxia; Yu,C,Yung; Kelly,Jennifer; Kaufman,Kenneth; Kitzmiller,Kathryn; Hikami,Koki; Arnett,Frank; Kimberly,Robert; Vyse,Timothy; Bae,Sang-Chcol; Alarcon-Riquelme,Marta; Moser,Kathy; Gilkeson,Gary; Merrill,Joan; James,Judith; Jacob,Chaim; Grossman,Jennifer; Hughes,Anne; Goodship,Timothy; Tsuchiya,Naoyuki; Hahn,Bevra; Shen,Nan; Harley,John; Tsao,Betty. 2008. Association of complement factor H haplotype and the CFHR3/CFHR1 deletion with SLE. In 72nd Annual Scientific Meeting of the American-College-of-Rheumatology/43rd Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals
  • Cohen,Robert,A; Bayliss,George; Crispin,Jose,C; Kane-Wanger,Gwen,F; Van Beek,Christine,A; Kyttaris,Vasileios,C; Avalos,Ingrid; Yu,C,Yung; Tsokos,George,C; Stillman,Isaac,E. 2008. T cells and in situ cryoglobulin deposition in the pathogenesis of lupus nephritis.  CLINICAL IMMUNOLOGY. Vol. 128, no. 1. (July): 1-7.
  • Shontz,Kimberly,M; Zhou,Bi; Yu,C-Yung; Su,Baogen,Y. 2008. Cloning and functional analysis of the swine eNOS promoter.  DNA SEQUENCE. Vol. 19, no. 1. (February): 62-67.
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