Center for Childhood Cancer

Mission

To expand the understanding of the pathogenesis of childhood cancer and to improve strategies for diagnosis and treatment.

Areas of Focus

• Biology and therapy of rhabdomyosarcoma and other childhood tumors

• Chemotherapy of childhood solid tumors

• Regulation of alternative pre-mRNA splicing

• Regulation and function of tumor suppressor genes

• Oncolytic viral therapy in pediatric brain tumors

Pediatric Preclinical Testing Program

• The Pediatric Preclinical Testing Program (PPTP) is a comprehensive program to systematically evaluate new agents against childhood solid tumor and leukemia models, ultimately contributing to the goal of identifying more effective treatments for children with cancer.

Affiliations and Collaborations

• Children's Oncology Group

• The Ohio State University Comprehensive Cancer Center

• The James Cancer Hospital and Solove Research Institute

• Nationwide Children's Hospital Division of Hematology and Oncology