Bryce A. Kerlin, MD :: Nationwide Children’s Hospital, Columbus, Ohio

Contact Information

Hematology & Oncology
700 Children's Dr
Columbus, OH 43205 [ map ]
PH: (614) 722-3550
FX: (614) 722-3369
Email Me
The Research Institute at Nationwide Children's Hospital
700 Children's Drive
Columbus, OH 43205 [ map ]

Location Information for Patients

Main Campus


Dr. Kerlin is an Investigator in the Center for Clinical & Translational Research at Nationwide Children’s Research Institute, a member of the Hematology/Oncology/BMT Division, and an Associate Professor of Pediatrics at The Ohio State University College of Medicine. His research is focused on the translational epidemiology of pediatric thrombosis, focusing on the clarification of biomarkers and clinical features linked to thrombosis, especially in pediatric kidney disease. He actively participates in clinical trials for new treatments in hemostasis and thrombosis, including new medications for hemophilia, von Willebrand disease, and blood clots. Dr. Kerlin is voted among the “Best Doctors in America”.


  • Male

Languages Spoken:

  • English

Research Interests

Research Center:

Research Funding*:

  • Patient and Family Support Group for Hemophilia Clinic, Hemophilia Foundation of Michigan/Cascade Hemophilia Consortium

Education and Training

Medical School

  • Medical College of Wisconsin

Post Doctoral

  • Blood Research Institute: The Blood Center of Southeastern Wisconsin


  • Medical College of Wisconsin and Children’s Hospital of Wisconsin

Undergraduate School

  • Purdue University

Medical School

  • Medical College of Wisconsin
    Date Completed: 05/18/1996


  • Phoenix Children's Hospital
    Date Completed: 06/30/1997


  • Phoenix Children's Hospital
    Date Completed: 06/30/1999


  • Medical College of Wisconsin
    Date Completed: 06/30/2002


  • Pediatrics


  • Hematology & Oncology


  • Pediatric Hematology Oncology

Date of Appointment at Nationwide Children’s Hospital:

  • 12/31/2004

Professional Experience


  • Director of Hematology, Nationwide Children's Hospital


  • Tumor Board,  Nationwide Children's Hospital


  • Pharmacy & Therapeutics, Nationwide Children's Hospital


  • Director, Nationwide Children's Hospital Hemophilia & Bleeding Disorders Program


  • Board Member, Ohio Bleeding Disorders Council


  • Pharmacy & Therapeutics Committee, Children's Hospital of San Diego


  • Medical Director, Hemophilia Association of San Diego County


  • Transfusion Medicine Committee, Children's Hospital of San Diego


  • Cancer Committee, Children's Hospital of San Diego


  • Director, San Diego Regional Pediatric Hemophilia Program


  • Tumor Board; Children's Hospital of San Diego


  • Tumor Board; Children's Hospital of Wisconsin


  • Director, Resident as Teacher Program; Phoenix Children’s Hospital/Maricopa Medical Center Pediatric Residency Program


  • Chairman, House Staff Social Committee; Phoenix Children’s Hospital/Maricopa Medical Center Pediatric Residency Program


  • Walsh CE, Soucie JM, Miller CH; the United States Hemophilia Treatment Center Network. 2015. Impact of inhibitors on hemophilia A mortality in the United States.  AMERICAN JOURNAL OF HEMATOLOGY. Vol. 90, no. 5. (May): 400-405.
  • Brand-Staufer B, Carcao M, KERLIN BA, Will A, William M, Tornoe CW, Sandberg Lundblad M, Nugent D. 2015. Pharmacokinetic characterization of recombinant factor XIII (FXIII)-A2 across age groups in patients with FXIII A-subunit congenital deficiency.  Haemophilia. Vol. 21, no. May: 380-385. PubMed ID: 25643920
  • Kerlin BA, Smoyer WE, Tsai J, Boulet SL. 2015. Healthcare burden of venous thromboembolism in childhood chronic renal diseases.  Pediatric Nephrology. Vol. 30, no. 5. (May): 829-837. PubMed ID: 25487668
  • KERLIN BA; Smoyer WE; Tsai J; Boulet SL. 2015. Healthcare burden of venous thromboembolism in childhood chronic renal diseases.  PEDIATRIC NEPHROLOGY. Vol. 30, no. 5. (May): 829-837.
  • KERLIN BA, Waller AP, Sharma R, Chanley MA, Nieman MT, Smoyer WE. 2015. Disease Severity Correlates with Thrombotic Capacity in Experimental Nephrotic Syndrome.  Journal of the Amercian Society of Nephrology: JASN. Vol. Epub, no. April: eASN.2014111097. PubMed ID: 25855774
  • Flood VH, Schlauderaff AC, Haberichter SL, Slobodianuk TL, Jacobi PM, Bellissimo DB, Christopherson PA, Friedman KD, Gill JC, Hoffmann RG, Montgomery RR, Zimmerman Program Investigators. 2015. Crucial role for the VWF A1 domain in binding to type IV collagen.  BLOOD. Vol. 125, no. 14. (April): 2297-2304.
  • KERLIN BA, Stephens JA, Hogan MJ, Smoyer WE, O'Brien SH. 2015. Development of a pediatric-specific clinical probability tool for diagnosis of venous thromboembolism: a feasibility study.  Pediatric Research. Vol. 3, no. 77. (March): 463-471. PubMed ID: 25518012
  • Carpenter SL, Soucie JM, Presley RJ, Ragni MV, Wicklund BM, Silvey M, Davidson H; Hemophilia Treatment Center Network Investigators. 2015. Hepatitis B vaccination is effective by subcutaneous route in children with bleeding disorders: a universal data collection database analysis.  HAEMOPHILIA. Vol. 21, no. 1. (January): E39-E43.
  • Elbatarny M, Mollah S, Grabell J, Bae S, Deforest M, Tuttle A, Hopman W, Clark DS, Mauer AC, Bowman M, Riddel J, Christopherson PA, Montgomery RR, Zimmerman Program Investigators, Rand ML, Coller B, James PD. 2014. Normal range of bleeding scores for the ISTH-BAT: adult and pediatric data from the merging project.  HAEMOPHILIA. Vol. 20, no. 6. (November): 831-835.
  • Lane H, Siddiqi AE, Ingram-Rich R, Tobase P, Scott Ward R; Universal Data Collection Joint Outcome Working Group; Hemophilia Treatment Center Network Study Investigators. 2014. Functional outcomes following ankle arthrodesis in males with haemophilia: analyses using the CDC's Universal Data Collection surveillance project.  HAEMOPHILIA. Vol. 20, no. 5. (September): 709-715.
  • Sidonio RF, Mili FD, Li T, Miller CH, Hooper WC, DeBaun MR, Soucie M; Hemophilia Treatment Centers Network. 2014. Females with FVIII and FIX deficiency have reduced joint range of motion.  AMERICAN JOURNAL OF HEMATOLOGY. Vol. 89, no. 8. (August): 831-836.
  • Ullman M, Zhang QC, Brown D, Grant A, Soucie JM; on Behalf of the Hemophilia Treatment Center Network Investigators. 2014. Association of overweight and obesity with the use of self and home-based infusion therapy among haemophilic men.  HAEMOPHILIA. Vol. 20, no. 3. (May): 340-348.
  • Puetz J, Soucie JM, Kempton CL, Monahan PE; Hemophilia Treatment Center Network (HTCN) Investigators. 2014. Prevalent inhibitors in haemophilia B subjects enrolled in the Universal Data Collection database.  HAEMOPHILIA. Vol. 20, no. 1. (January): 25-31.
  • KERLIN B, Brand B, Inbal A, Halimeh S, Nugent D, Lundblad M, Tehranchi R. 2014. Journal of Thrombosis and Haemostasis.  Pharmacokinetics of recombinant FXIII at steady-state in patients with congenital FXIII A-subunit deficiency.. Vol. 12, no. January: 2038-2043.
  • Rheault MN, Wei C-C, Hains DS, Wang W, KERLIN BA, Smoyer WE. 2014. Increasing Frequency of Acute Kidney Injury Amongst Children Hospitalized with Nephrotic Syndrome Pediatric Nephrology.  Pediatric Nephrology. Vol. 29, no. 1. (January): 139-147.
  • Sood SL, Cuker A, Wang C, Metjian AD, Chiang EY, Soucie JM, Konkle BA; HTCN Study Investigators. 2013. Similarity in joint function limitation in Type 3 von Willebrand's disease and moderate haemophilia A.  HAEMOPHILIA. Vol. 19, no. 4. (July): 595-601.
  • KERLIN BA, Haworth K, Smoyer WE. 2013. Venous Thromboembolism in Pediatric Nephrotic Syndrome.  Pediatric Nephrology. Vol. Epub, no. June: 1-9.
  • Soucie JM, De Staercke C, Monahan PE, Recht M, Chitlur MB, Gruppo R, Hooper WC, Kessler C, Kulkarni R, Manco-Johnson MJ, Powell J, Pyle M, Riske B, Sabio H, Trimble S, the US Hemophilia Treatment Center Network. 2013. Evidence for the transmission of parvovirus B19 in patients with bleeding disorders treated with plasma-derived factor concentrates in the era of nucleic acid test screening.  TRANSFUSION. Vol. 53, no. 6. (June): 1217-1225.
  • Kelly D, Zhang QC, Soucie MJ, Manco-Johnson M, DiMichele D, the Joint Outcome Subcommittee of the Coordinating Committee for the Universal Data Collection Database and the Hemophilia Treatment Center Network Investigators. 2013. Prevalence of clinical hip abnormalities in haemophilia A and B: an analysis of the UDC database.  HAEMOPHILIA. Vol. 19, no. 3. (May): 426-431.
  • Gupta S, Siddiqi A, Soucie JM, Manco-Johnson M, Kulkarni R, Lane H, Ingram-Rich R, Gill JC, of the Joint Outcomes Committee of the Universal Data Collection and the Hemophilia Treatment Centres Network. 2013. The effect of secondary prophylaxis versus episodic treatment on the range of motion of target joints in patients with haemophilia.  BRITISH JOURNAL OF HAEMATOLOGY. Vol. 161, no. 3. (May): 424-433.
  • Flood VH, Gill JC, Friedman KD, Christopherson PA, Jacobi PM, Hoffman RG, Montgomery RR, Haberichter SL, and the Zimmerman Program Investigators. 2013. Collagen Binding Provides a Sensitive Screen for Variant von Willebrand Disease.  CLINICAL CHEMISTRY. Vol. 59, no. 4. (April): 684-691.
  • Abshire TC, Federici AB, Alvarez MT, Bowen J, Carcao MD, Cox Gill J, Key NS, Kouides PA, Kurnik K, Lail AE, Leebeek FW, Makris M, Mannucci PM, Winikoff R, Berntorp E, VWD PN. 2013. Prophylaxis in severe forms of von Willebrand's disease: results from the von Willebrand Disease Prophylaxis Network (VWD PN).  HAEMOPHILIA. Vol. 19, no. 1. (January): 76-81.
  • Setty BA, O’Brien SH, KERLIN BA. 2012. Pediatric Venous Thromboembolism in the United States: A Tertiary Care Complication of Chronic Diseases.  Pediatric Blood & Cancer. Vol. 59, no. August: 258-264. PubMed ID: 22038730
  • Sladky JL, Klima J, Grooms L, KERLIN BA, O'Brien SH. 2012. The PFA-100® does not predict delta-granule platelet storage pool deficiencies.  Haemophilia. Vol. 18, no. 4. (July): 626-629. PubMed ID: 22226191
  • Carpenter SL, Soucie JM, Sterner S, Presley R, Hemophilia Treatment Center Network (HTCN). 2012. Increased prevalence of inhibitors in Hispanic patients with severe haemophilia A enrolled in the Universal Data Collection database.  HAEMOPHILIA. Vol. 18, no. 3. (May): e260-e265.
  • KERLIN BA. 2012. Current and Future Management of Pediatric Venous Thromboembolism.  Am J Hematol. Vol. 87, no. May: S68-S74. PubMed ID: 22367975
  • KERLIN BA Ayoob R, Smoyer WE. 2012. Epidemiology and Pathophysiology of Nephrotic Syndrome-Associated Thromboembolic Disease.  Clin J Am Soc Nephrol. Vol. 7, no. March: 513-520.
  • Hay CR, DiMichele DM, International Immune Tolerance Study. 2012. The principal results of the International Immune Tolerance Study: a randomized dose comparison.  BLOOD. Vol. 119, no. 6. (February): 1335-1344.
  • Byams VR, Kouides PA, Kulkarni R, Baker JR, Brown DL, Gill JC, Grant AM, James AH, Konkle BA, Maahs J, Dumas MM, McAlister S, Nance D, Nugent D, Philipp CS, Soucie JM, Stang E, Haemophilia Treatment Centres Network Investigators. 2011. Surveillance of female patients with inherited bleeding disorders in United States Haemophilia Treatment Centres.  HAEMOPHILIA. Vol. 17, no. July: 6-13.
  • Soucie JM, Wang C, Forsyth A, Funk S, Denny M, Roach KE, Boone D, Hemophilia Treatment Center Network. 2011. Range of motion measurements: reference values and a database for comparison studies.  HAEMOPHILIA. Vol. 17, no. 3. (May): 500-507.
  • KERLIN BA. 2011. Pulmonary morbidity of catheter-related pediatric venous thromboembolism: Old problem, new worry.  CRITICAL CARE MEDICINE. Vol. 39, no. 5. (May): 1234-1235.
  • Soucie JM, Wang C, Siddiqi A, Kulkarni R, Recht M, Konkle BA, Hemophilia Treatment Center Network. 2011. The longitudinal effect of body adiposity on joint mobility in young males with Haemophilia A.  HAEMOPHILIA. Vol. 17, no. 2. (March): 196-203.
  • Karsies TJ, Nicol KK, Galantowicz ME, Stephens JA, KERLIN BA. 2010. Thrombotic Risk of Recombinant Factor Seven in Pediatric Cardiac Surgery: A Single Institution Experience.  Annals of Thoracic Surgery. Vol. 89, no. 2. (February): 570-577.
  • KERLIN BA. 2009. Thrombolysis for Pediatric Venous Thromboembolism: Is it Time for a Trial?.  PEDIATRIC BLOOD & CANCER. Vol. 53, no. 6. (December): 920-921.
  • Kulkarni R, Soucie JM, Lusher J, Presley R, Shapiro A, Gill J, Manco-Johnson M, Koerper M, Mathew P, Abshire T, DiMichele D, Hoots K, Janco R, Nugent D, Geraghty S, Evatt B, Haemophilia Treatment Center Network Investigators. 2009. Sites of initial bleeding episodes, mode of delivery and age of diagnosis in babies with haemophilia diagnosed before the age of 2 years: a report from The Centers for Disease Control and Prevention's (CDC) Universal Data Collection (UDC) project.  HAEMOPHILIA. Vol. 15, no. 6. (November): 1281-1290.
  • KERLIN BA, Blatt NB, Fuh B, Zhao S, Lehman A, Blanchong C, Mahan JD, Smoyer WE. 2009. Epidemiology and Risk Factors for Thromboembolic Complications of Childhood Nephrotic Syndrome: A Midwest Pediatric Nephrology Consortium (MWPNC) Study.  The Journal of Pediatrics. Vol. 155, no. July: 105-10. PubMed ID: 19394032
  • Metjian AD, Wang C, Sood SL, Cuker A, Peterson SM, Soucie JM, Konkle BA, The HTCN Study Investigators. 2009. Bleeding symptoms and laboratory correlation in patients with severe von Willebrand disease.  HAEMOPHILIA. Vol. 15, no. 4. (July): 918-925.
  • KERLIN BA. 2009. Screening for Anemia. In Textbook of Pediatric Care. 1st ed. Edited by McInerny TK, Adam HM, Campbell D, Kamat DK, Kelleher KJ. Elk Grove Village, IL: American Academy of Pediatrics.
  • Mast KJ, Nunes ME, Ruymann FB, KERLIN BA. 2009. Desmopressin Responsiveness in Children with Ehlers-Danlos Syndrome Associated Bleeding Symptoms.  British Journal of Haematology. Vol. 144, no. January: 230-233.
  • Hyatt SA, Wang W, KERLIN BA, O'Brien S. 2009. Applying Diagnostic Criteria for Type 1 von Willebrand Disease to a Pediatric Population.  Pediatric Blood & Cancer. Vol. 52, no. January: 102-107.
  • Klopfenstein KJ, Clayton J, Rosselet R, KERLIN B, Termuhlen A, Gross T. 2009. Prevalence of Abnormal Bone Density of Pediatric Patients Prior to Blood or Marrow Transplant.  Pediatric Blood & Cancer. Vol. 53, no. January: 675-677.
  • KERLIN BA, Blatt NB, Fuh B, Zhao S, Lehman A, Blanchong C, Mahan JD, Smoyer WE. 2009. Epidemiology and Risk Factors for Thromboembolic Complications of Childhood Nephrotic Syndrome: A Midwest Pediatric Nephrology Consortuim (MWPNC) Study.  The Journal of Pediatrics. Vol. 155, no. January: 105-110. PubMed ID: 19394032
  • KERLIN BA. 2009. Thrombolysis for Pediatric Venous Thromboembolism: Is it Time for a Trial?.  Pediatric Blood & Cancer. Vol. 53, no. January: 920-921.
  • Sharathkumar A, Hardesty B, Greist A, Salter J, KERLIN B, Heiman M, Sulkin M, Shapiro A. 2009. Variability in Bleeding Phenotype in Amish Carriers of Hemophilia B with the C31008T Mutation.  Haemophilia. Vol. 15, no. January: 91-100.
  • Rose MJ, Nicol KK, Skeens MA, Gross TG, KERLIN BA. 2008. Congenital Amegakaryocytic Thrombocytopenia: the Diagnostic Importance of Combining Pathology with Molecular Genetics.  Pediatric Blood & Cancer. Vol. 50, no. January: 1263-1265.
  • Lo W, Zamel K, Ponnappa K, Allen A, Chisolm D, Tang M, KERLIN B, Yeates KO. 2008. The Cost of Pediatric Stroke Care and Rehabilitation.  Stroke. Vol. 39, no. January: 161-165.
  • Varga EA, KERLIN BA, Wurster MW. 2008. Social and Ethical Controversies in Thrombophilia Testing and Updates on Genetic Risk Factors for Venous Thromboembolism.  Seminars in Thrombosis and Hemostasis. Vol. 34, no. January: 549-561.
  • Davis RL, Mosesson MW, KERLIN BA, Canner JA, Ruymann FB, Brennan SO. 2007. Fibrinogen Columbus: a Novel gamma Gly200Val Mutation Causing Hypofibrinogenemia in a Family with Associated Thrombophilia.  Haematologica. Vol. 92, no. January: 1151-1152.
  • Nicol K, Swedan N, Moder P, Kahwash S, Rose M, KERLIN B. 2006. Hemolytic Anemia in a 5-Year-Old Child.  LabMedicine. Vol. 37, no. January: 746-748.
  • Savelli SL, Kerlin BA, Springer MA, Monda K, Thornton J, Blanchong CA: Recommendations for Screening for Thrombophilic Tendencies in Teenage Females Prior to Contraceptive Initiation.  Journal of Pediatric and Adolescent Gynecology 19:313-6, 2006. PubMed ID: 16873040
  • Savelli SL, KERLIN BA, Springer MA, Monda K, Thornton J, Blanchong CA. 2006. Recommendations for Screening for Thrombophilic Tendencies in Teenage Females Prior to Contraceptive Initiation.  Journal of Pediatric and Adolescent Gynecology. Vol. 19, no. January: 313-316. PubMed ID: 16873040
  • Loh KC, Willert J, Meltzer H, Roberts W, KERLIN B, Kadota R, Levy M, White G, Geddis A, Schiff D, Martin L, Yu A, Kung F, Spear MA. 2005. Temozolomide and Radiation for Aggressive Pediatric Central Nervous System Malignancies.  Journal of Pediatric Hematology/Oncology. Vol. 27, no. 5. (January): 254-258.
  • Weiler H, KERLIN B, Lytle MC. 2004. Factor V Leiden polymorphism modifies sepsis outcome: Evidence from animal studies.  CRITICAL CARE MEDICINE. Vol. 32, no. 5. (May): S233-S238.
  • KERLIN BA, Cooley BC, Isermann BH Hernandez I, Sood R, Zogg M, Hendrickson SB, Mosesson MW, Lord S, Weiler H. 2004. Cause-Effect Relation between Hyperfibrinogenemia and Vascular Disease.  Blood. Vol. 103, no. 5. (January): 1728-1734.
  • Weiler H, KERLIN B, Lytle MC. 2004. Factor V Leiden Polymorphism Modifies Sepsis Outcome: Evidence from Animal Studies.  Critical Care Medicine. Vol. 32, no. 5 Supplement. (January): S233-S238. PubMed ID: 15118524
  • KERLIN BA, Yan SB, Isermann BH, Brandt JT, Sood R, Basson BR, Joyce DE, Weiler H, Dhainaut J-F. 2003. Survival Advantage Associated with Heterozygous Factor V Leiden Mutation in Patients with Severe Sepsis and in Mouse Endotoxemia.  Blood. Vol. 102, no. 9. (January): 3085-3092.
  • Greenbaum LA, KERLIN BA, Van Why S, Punzalan RC, Trost BA, Pan CG, Scott JP. 2003. Concurrent Poststreptococcal Glomerulonephritis and Autoimmune Hemolytic Anemia.  Pediatric Nephrology. Vol. 18, no. 12. (January): 1301-1303.
  • Weiler H, Lindner V, KERLIN B, Isermann BH, Hendrickson SB, Cooley BC, Meh DA, Mosesson MW, Shworak NW, Post MJ, Conway EM, Ulfman LH, von Andrian UH, Weitz JI. 2001. Characterization of a Mouse Model for Thrombomodulin Deficiency.  Arteriosclerosis, Thrombosis, and Vascular Biology. Vol. 21, no. 9. (January): 1531-1537.
  • Malec LM, Moore CG, Bennett CM, Yee D, KERLIN BA, Witmer C, Kulkarni R, Gupta S, Gunawardena S, Kouides PA, Brown D, Bujnicki HL, Ragni MV. Validation Study of the Composite Score to Identify Von Willebrand Disease in Children.  Journal of Pediatric Hematology/Oncology.
  • Woods G, KERLIN BA. Childhood Venous Thromboembolism. In Succinct Pediatrics. Edited by Feld L and Mahan JD.
  • Sharma R, KERLIN BA. Screening for Anemia. In American Academy of Pediatrics Textbook of Pediatric Care. Edited by Adam H, Campbell D, DeWitt T, Foy J, Kamat D, Baum R, Kelleher K, eds.
  • Madhusudhan T, KERLIN BA, Isermann B. Emerging Role of Coagulation Proteases in Kidney Disease.  Nature Reviews Nephrology.
  • Rheault MN, Zhang L, Selewski DT, Kallash M, Tran CL, Seamon M, Katsoufis C, Ashoor I, Hernandez J, Supe-Markovina K, D'alessandri-Silva C, DeJesus-Gonzalez N, Vasylyeva TL, Formeck C, Woll C, Gbadegesin R, Geier P, Devarajan P, Carpenter SL, KERLIN BA, Smoyer WE. Acute Kidney Injury is Common in Children Hospitalized with Nephrotic Syndrome: A Midwest Pediatric Nephrology Consortium Study.  Clinical Journal of the American Society of Nephrology.
  • Woods GM, KERLIN BA, O’Brien SH, Bonny AE. A Review of Hormonal Contraception and Venous Thromboembolism in Adolescents.  Journal of Pediatric and Adolescent Gynecology.

Awards, Honors and Organizations

  • Listed, Best Doctors in America

Pediacast Interview with Dr. Bryce Kerlin

Join Dr. Mike of Pediacast and Dr Bryce Kerlin as they describe Factor V Leiden. This relatively new disease was discovered in 1994 and results in the formation of blood clots where they aren't needed.


Pediacast with Dr. Mike Patrick

Listen now »

Listen to Dr. Kerlin on PediaCast

Factor V Leiden – PediaCast 175
Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000