The BCR is a CAP-accredited laboratory and biorepository within the Biopathology Center (BPC) at Nationwide Children's Hospital.
The Biospecimen Core Resource (BCR) at Nationwide Children’s Hospital serves as the centralized tissue processing and clinical data collection center for The Cancer Genome Atlas (TCGA). TCGA, a coordinated effort supported by the National Cancer Institute (NCI) and the National Human Genome Research Institute, is working to accelerate the comprehensive understanding of the genetics of cancer using innovative genome analysis technologies. As the primary interface between the TCGA program office and the Tissue Source Sites (TSS), the BCR coordinates sample shipments and data collection with institutions around the world.
The BCR is a CAP-accredited laboratory and biorepository with the Biopathology Center (BPC) at Nationwide Children’s Hospital. Nationwide Children’s was selected to serve as the BCR for TCGA due to the BPC’s reputation for quality biobanking. More than 20 years ago, pediatric cancer pathologist Stephen J. Qualman, MD, was ahead of his time in realizing the importance of developing biobanking as a scientific discipline. A sophisticated, high-quality biobanking effort has existed at Nationwide Children’s since the late 1980s, and now serves as the biorepository for three of the NCI Cooperative Cancer Groups: Children’s Oncology Group (COG), Gynecologic Oncology Group (GOG), and SWOG (formerly Southwest Oncology Group). The BPC also serves as a centralized clinical reference laboratory for COG, performing testing to assign patients to risk-based therapies.