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Laboratory Test Directory

Zinc Protoporphyrin (ZPP), Whole Blood


Name Method Department Units
Zinc Protoporphyrin (ZPP), Whole Blood Quantitative Hematofluorometry
Send Out µmol ZPP/ mol Hem

Specimen Requirements

Whole blood

Container Type Container Size Specimen Volume

Royal blue (EDTA)

6 mL 1 mL

Purple tube (EDTA)

3 mL 1 mL

Room temperature - 30 hour(s)
Refrigerated - 5 week(s)

Specimen Preparation

  • Mix by gentle inversion immediately after collection
  • Do not centrifuge
  • Do not freeze
  • Transport to laboratory as soon as possible

Reasons for Rejection

  • Wrong collection tube
  • Clotted specimen
  • Centrifuged specimen
  • Frozen specimen
  • Hemolyzed specimen


Elevated ZPP results are seen in early and late iron deficiency, the anemia of chronic disease, chronic lead poisoning, and erythropoietic protoporphyria.  Elevated bilirubin or riboflavin and hemolyzed, clotted, or improperly aliquoted specimens may falsely increase the ZPP concentration.

CPT Code

  • 84202