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Laboratory Test Directory

Chromosome Analysis, Fetal Fluid


Name Method Department Units
Fetal Fluid Chromosome Analysis Cell Culture
Chromosomal analysis

Specimen Requirements

Body fluid

Container Type Container Size Specimen Volume

Sterile container

N/A 20 mL-35 mL

Room temperature - 24 hour(s)

Specimen Preparation

  • Do not add fixative
  • Do not freeze
  • Do not centrifuge
  • Do not refrigerate
  • Keep at room temperature

Reasons for Rejection

  • Fixed specimen
  • Centrifuged specimen
  • Frozen specimen
  • Delayed or improper handling
  • Not received within specified time frame


Submission of completed "Cytogenetics & Molecular Genetics PRENATAL Test Requisition Form" is required; please indicate the source of fetal fluid on the form. For AneuVysion FISH screen for common aneuploidies (chromosomes 13, 18, 21, X and Y), submit additional 5-10 mL fluid. For infectious disease PCR, submit 2-3 mL additional fluid. Please keep fetal fluid sample at room temperature and send to the laboratory within 24 hours from collection time. Please note that depending on the number of viable cells contained in the submitted fluid, cell culture and chromosome analysis result may take longer than quoted TAT, or cell culture may fail and no chromosome analysis result may be available.

CPT Code

  • 88235
  • 88267
  • 88280