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Laboratory Test Directory

Thiopurine Metabolites


Name Method Department Units
6 MP Metabolites Quantitative High Performance Liquid Chromatography
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6-TGN (thioguanine nucleotide) and 6-MMPN (methyl mercaptopurine nucleotide)

Specimen Requirements

Whole blood

Container Type Container Size Specimen Volume

Purple tube (EDTA)

6 mL 5 mL

Refrigerated - 8 day(s)
Room temperature - 3 day(s)

Specimen Preparation

  • Transport to laboratory as soon as possible
  • Mix by gentle inversion immediately after collection

Reasons for Rejection

  • Centrifuged specimen
  • Non EDTA specimen


Transport immediately to laboratory. Not the same as 6MP genotype or phenotype. Minimum volume will not allow for repeat testing.

CPT Code

  • 82542