Research News

Study Divides Breast Cancer Into Four Distinct Types

Investigators have identified four genetically distinct types of breast cancer in a study published online in the journal, Nature.  Nationwide Children’s Hospital was one of several institutions involved in this study.  The research analyzes tumors from 825 patients and is the first comprehensive genetic breast cancer analysis. 

About 1 in 8 U.S women will develop invasive breast cancer and the disease kills more than 35,000 women in the United States each year.  The breast cancer report is the third study of its kind from The Cancer Genome Atlas project, of which Nationwide Children’s is a partner.  This multi-site federal project plans to profile genomic changes in 20 cancer types and previously reported on lung and colorectal cancer.  
 
Within the four breast cancer types, the team found at least 40 genetic alterations that are driving tumor growth and that may be targets for drug treatment.  

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