Susan Hodge :: Nationwide Children's Hospital, Columbus, Ohio

Susan E Hodge, DSc

Susan E Hodge, DSc

Contact Information

The Research Institute at Nationwide Children's Hospital
575 Children's Crossroad
Columbus, OH 43215 [ map ]
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Dr. Hodge has extensive experience and an international reputation in mathematical modeling in human genetics and genetic epidemiology. Originally trained in applied mathematics (DSc, Applied Mathematics, 1976), Dr. Hodge has made numerous recognized contributions to statistical genetics. On the theoretical/mathematical side, she has published influential papers in linkage analysis methodologies, association analysis, efficient genetic study design, ascertainment issues, genetic heterogeneity, genetic anticipation, the use of SNPs, population stratification, multipoint mapping, etc. On the applied side, she worked in the field of psychiatric genetics for over 25 years, at Washington University in St. Louis (1977-78), at UCLA (1978-1988), and at Columbia University (1988-2012), where she was involved in a long-term project investigating the genetics of panic disorder. She has also worked on the genetics of other common diseases, such as type 1 diabetes, multiple sclerosis, psoriasis, and primary pulmonary hypertension. She has published widely in respected journals in human genetics and mathematical modeling (American Journal of Human Genetics, American Journal of Medical Genetics, Annals of Human Genetics, European Journal of Human Genetics, Genetic Epidemiology, Biometrics, Human Heredity, Biological Psychiatry, etc.) She has been a member for many years of the American Society of Human Genetics, the Biometrics Society, and the International Genetic Epidemiology Society (Founding Member), and she has served as a Associate Editor of Human Heredity since 1998. She directed a training program (the Genetics of Complex Disorders program) at Columbia University (2002-2012) and is widely recognized as an unusually gifted lecturer & teacher. In 2012 Dr. Hodge moved to Columbus to join the faculties of Ohio State University and of the Battelle Center for Mathematical Medicine in The Research Institute at Nationwide Children’s Hospital, where she expects to continue her research on statistical methods for analyzing human genetic diseases.

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Languages Spoken:

  • English

Research Interests

Education and Training

Undergraduate School

  • Antioch College, Yellow Springs, Ohio
    Date Completed: 05/01/1968


  • Washington University, St. Louis, Missouri
    Date Completed: 05/01/1976

Professional Experience


  • Professor of Pediatrics, College of Medicine, The Ohio State University, Columbus, OH


  • Professor, Battelle Center for Mathematical Medicine, The Research Institute at Nationwide Children’s Hospital, Columbus, OH


  • Professor of Clinical Biostatistics (in Psychiatry) Columbia University in the City of New York


  • Research Scientist, Division of Clinical-Genetic Epidemiology, New York State Psychiatric Institute


  • Associate Professor in Biomathematics and Psychiatry, UCLA


  • Member, Division of Medical Genetics, UCLA


  • Assistant Professor in Biomathematics and Psychiatry, UCLA


  • Hodge, SE., Hager, VR., Greenberg, DA. 2016. Using Linkage Analysis to Detect Gene-Gene Interactions. 2. Improved Reliability and Extension to More-Complex Models.  PLos One. Vol. 11, no. 1. (January): ee0146240.
  • Das, J., Mukherjee, S., Hodge, SE. 2015. Maximum Entropy Estimation of Probability Distribution of Variables in Higher Dimensions from Lower Dimensional Data.  Entropy. Vol. 17, no. 7. (July): 4986-4999.
  • Helbig, I., Hodge, S.E., and Ottman, R. 2013. Familial cosegregation of rare genetic variants with disease in complex disorders.  EUR J Hum Genet. Vol. 4, no. April: 444-50.
  • Vieland, V.J., Das, J., Hodge, S.E. and Seok, S.-C. 2013. Measurement of statistical evidence on an absolute scale following thermodynamic principles.  Theory in Biosciences. Vol. 132, no. March: 181-194.
  • Subaran, R., Talati, A., Hamilton, S.P., Adams, P., Weissman, M.M., Fyer, A.J., Hodge, S.E. 2012. A survey of putative anxiety-associated genes in panic disorder patients with and without bladder symptoms.  Psychiatric Genet. Vol. 22, no. December: 271-8.
  • Hodge, S.E., Subaran, R.L., Weissman, M.M., and Fyer, A.J. 2012. Designing case-control studies: Decisions about the controls.  AM J Psychiatry. Vol. 169, no. December: 785-789.
  • Madsen,Ann,M; Ottman,Ruth; Hodge,Susan,E. 2011. Causal Models for Investigating Complex Genetic Disease: II. What Causal Models Can Tell Us about Penetrance for Additive, Heterogeneity, and Multiplicative Two-Locus Models.  HUMAN HEREDITY. Vol. 72, no. 1. (January): 63-72.
  • Madsen,Ann,M; Hodge,Susan,E; Ottman,Ruth. 2011. Causal Models for Investigating Complex Disease: I. A Primer.  HUMAN HEREDITY. Vol. 72, no. 1. (January): 54-62.
Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000