Pulmonary Medicine Research and Innovation

Little girl receiving oxygen therapy

New Guidelines for Home Oxygen Therapy in Pediatric Patients

The American Thoracic Society (ATS) has just released the first national clinical practice guidelines for home oxygen therapy in children.

RBIII

Cystic Fibrosis Research and Development Program Awarded $2 Million Grant From Cystic Fibrosis Foundation

A team of researchers at Nationwide Children's Hospital and The Ohio State University (OSU) College of Medicine recently was awarded a $2 million grant over four years to continue development of the Cure CF Columbus Research and Development Program (C3 RDP).

Benjamin T. Kopp, MD

How Does Secondhand Smoke Exposure Harm Children With Cystic Fibrosis?

Altered immune and inflammatory responses hinder clearance of bacterial infections.

Richard Shell

FDA Approves Novel Gene Therapy for SMA

Children with SMA1, the number one genetic killer of babies under 2 years of age, fail to meet motor milestones and typically die or require permanent mechanical ventilation by age 2.

Cystic Fibrosis Modulators Improve Killing of Bacteria

Researchers Identify Proteins Triggering Imbalance of Cells in Chronic Lung Disease

A protein that triggers an imbalance of mucous and ciliated cells in patients with chronic lung disease could be a target for treatments to restore airways.

Do All Cystic Fibrosis Modulators Improve Killing of Bacteria?

Treated immune cells function properly to kill more bacteria, depending on the treatment and the bacteria.

Heart and Lungs

Current Pediatric Lung Transplant Trends

CF patients are more often requiring lung transplants later in life while there is a growing trend in children with refractory ARDS needing transplants.

Additional Research

Asthma Research

In 1999, the Section of Pulmonary Medicine at Nationwide Children’s was designated as an American Lung Association Asthma Clinical Research Center, one of 18 selected participants, only five of which are pediatric.

Cystic Fibrosis Research

Pulmonary Medicine at Nationwide Children’s Hospital has been involved in research related to cystic fibrosis (CF) since the early 1990s.

Cystic Fibrosis team in India

Mission Work in India

According to UNICEF data, the death rate for children under the age of 5 years is 43 per 1,000 live births in India. This means that 563,752 children will die this year, many without proper diagnosis of their diseases.