Necrotizing Enterocolitis Research

Primarily seen in premature infants, necrotizing enterocolitis (NEC) is the most common and most serious gastrointestinal disorder among hospitalized preterm infants. Despite improvements in clinical care and many previous clinical trials, the prognosis for newborns with NEC has not shown any significant improvement during the past 30 years and the mortality rate remains unchanged.  

Investigators at Nationwide Children’s Hospital are focused on protecting the intestines from NEC, primarily by investigating molecular triggers and developing potential therapeutic targets such as growth factors that may serve as cytoprotective agents against intestinal damage.

Learn more about our research by visiting the Center for Perinatal Research website.