Reasons for Rejection

• Fixed specimen
• Formalin Fixed Tissue
• Frozen specimen
• Delayed or improper handling

Comments

This test is intended for patients who have previously had abnormal chromosome results in the prenatal period (e.g. CVS, amniotic fluid, or PUBS chromosome analysis) or had abnormal chromosome result on postnatal blood sample and confirmation of previous result is desired on the tissue sample. This test will evaluate chromosomes in 5 cells in cultured tissue sample; if complete tissue chromosome analysis (evaluates 20 cells) is desired, order test code TCS. When submitting tissue from products of conception (POC), such as placenta, umbilcal cord, and/or fetal tissue sample completed POC Requistiion Form is required. When submitting postnatally obtained tissue sample, such as from skin biopsy and surgical specimen, submission of Genetic Test Requisition Form is required. Fresh tissue sample is needed for this test. Collected tissue sample should be placed in a sterile container containng tissue transport media or sterile saline, and tissue should be completely immersed in the media/saline. Do NOT expose to formalin or other fixatives, do NOT freeze. Transport the specimen to the laboratory as soon as possible at room temperature. If additional in-house or send-out testing on cultured fibroblasts is desired, please clearly indicate the desired testing on the lab order and call Cytogenetics lab and speak to a laboratory genetic counselor to coordinate additonal testing.