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Laboratory Test Directory

Protein C Activity


Name Method Department Units
Protein C Activity Clot detection
Core Lab, Coagulation %

Specimen Requirements

Platelet poor plasma

Container Type Container Size Specimen Volume

Blue plastic tube (Citrate)

2.7 mL 2.7 mL

Frozen - 2 week(s)


Blue plastic tube (Citrate)

1.8 mL 1.8 mL

Frozen - 2 week(s)

Specimen Preparation

  • Fill tubes to appropriate mark.
  • Mix by gentle inversion immediately after collection
  • Plasma must be platelet free
  • Centrifuge, remove plasma/serum and freeze

Reasons for Rejection

  • Over or under filled tube
  • Clotted specimen
  • Gross hemolysis
  • Not received within specified time frame
  • Wrong collection tube
  • Capillary specimen
  • Specimen collected in glass tube


Presence of high levels of Factor VIII, Heparin, or Thrombin Inhibitors may affect the test results. Please call the Coagulation Laboratory (614-722-5364) for further information. If sending frozen plasma: Centrifuge citrate tubes according to Lab policy, remove platelet-poor plasma, pool the plasma, aliquot and freeze. Send a minimum of two (2) aliquots of plasma.

CPT Code

  • 85303