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Laboratory Test Directory

POC Microarray with 5-Cell Chromosome Analysis

Components

Name Method Department Units
POC Microarray with 5-Cell Chromosome Analysis DNA extraction
Microarray analysis
Cell Culture
Chromosomal analysis
Cytogenetics

Specimen Requirements

Tissue (Fresh)

Container Type Container Size Specimen Volume
Preferred

Tissue culture transport media

N/A 1 cm cube or greater
Alternate

Sterile container with saline

N/A 1 cm cube or greater
Stability

Room temperature - 24 hour(s)
Refrigerated - 48 hour(s)

Specimen Preparation

  • Keep at room temperature or refrigerate
  • Transport to the lab immediately after collection
  • Do not freeze
  • Do not formalin fix the sample

Reasons for Rejection

  • Inadequate tissue
  • Delayed or improper handling
  • Wrong type of specimen
  • Tissue degradation
  • Formalin Fixed Tissue

Comments

Submission of a completed POC Genetic Test Requisition Form is required. To obtain a requisition form, please call Cytogenetics lab at (614) 722-5321. Submission of maternal blood speicmen (4mL EDTA) is strongly recommended to evaluate for maternal cell contamination of the submitted POC specimen.

This test inlcudes Microarray Analysis and 5-Cell Chromosome Analysis (5-Cell Abbreviated Karyotype) performed on products of conception (POC) tissue specimen. If maternal blood specimen is submitted, then maternal cell contamination study will automatically be performed. The number of chromosomes will be evaluated in 5 cultured cells and the full karyotype analysis will be performed on 1 of the 5 cells.

Fresh tissue specimen from the POC is required for this test. If return of tissue sample is desired, please indicate the tissue return request on the test requisition form as well as return shipping address, contact person name and phone number. If only frozen or formalin-fixed sample is available, please call the laboratory (614) 722-5321 to speak with a laboratory genetic cousnelor to discuss alternative test options. 

PLEASE NOTE: Due to the limited number of cells evaluated by this study for chromosome analysis, mosaicism for chromosomal abnormality may not be detected by this study. If mosaicism is suspected, an alternate testing "Tissue Chromosome Analysis (test code: TCS)" that evaluates 20 cells is available, with an option for "Mosaicism Study" that evaluates 50 cells.

CPT Code

  • 88233
  • 88261
  • 81229