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Laboratory Test Directory

Chromosome Analysis (High Resolution), Peripheral Blood

Components

Name Method Department Units
Peripheral Blood, Chromosome Analysis Chromosomal analysis
Cytogenetics

Specimen Requirements

Whole blood

Container Type Container Size Specimen Volume
Preferred

Green tube (Sodium heparin), No Gel

10 mL 5 mL-8 mL Adult
Preferred

Green tube (Sodium heparin), No Gel

10 mL 5 mL-8 mL Child
Preferred

Green tube (Sodium heparin), No Gel

3 mL 1 mL-3 mL Infant
Stability

Room temperature - 24 hour(s)

Specimen Preparation

  • Do not centrifuge
  • Do not freeze
  • Do not refrigerate
  • Keep at room temperature

Reasons for Rejection

  • Centrifuged specimen
  • Collected in tube with gel separator
  • Wrong collection tube
  • Frozen specimen
  • Clotted specimen

Comments

Please click on the Lab Form Link in the Forms Section to print and complete the Genetic Test Requisition Form. Submission of a completed Genetics Test Requisition Form is required. Please collect whole blood specimen into a Sodium Heparin tube (dark green-top tube without gel separator). DO NOT use Lithium Heparin tube or other types of Heparin tubes.

This test evaluates chromosomes in 20 cells (cultured lymphocytes) from peripheral blood sample. This test is used to diagnose or rule out numerical and structural chromosomal abnormalities such as aneuploidy, chromosome translocation, and chromosome inversion. This test is intended for constitutional (germline) study.

For newborn patients, STAT blood chromosome analysis is available at extra charge (see Test Code: STATPB), which provides a verbal preliminary result in 2 business days and faster written report turn-around-time. Please indicate "STAT" on the lab order if STAT analysis is desired. 

If evaluation of extra cells (beyond the routine 20 cells) is desired to rule out low-level mosaicism, please request "Mosaicism Study" on the lab order and 50 cells will be evaluated at extra charge.

If patient has a family history of known chromosome abnormality, please provide the family member's chromosome result information (attach a copy of test result if available). If the proband was tested at Nationwide Children's Hospital Cytogenetics Laboratory, please provide the proband name, date of birth, and accession number (if available).

Forms

Lab Form

CPT Code

  • 88230
  • 88262
  • 88289