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Laboratory Test Directory

Methylmalonic Acid


Name Method Department Units
Methylmalonic Acid Gas Chromatography/Mass spectrometry
Core Lab, Metabolic chemistry umol/L

Specimen Requirements

Plasma Spun, Serum Spun

Container Type Container Size Specimen Volume

Green tube (Lithium heparin), No Gel

3 mL 3 mL

Purple tube (EDTA)

3 mL 3 mL

Red tube, (no anticoagulant), No Gel

3 mL 3 mL

Refrigerated - 4 hour(s)
Frozen - Indefinite week(s)

Specimen Preparation

  • Place on ice immediately after collection
  • Centrifuge, remove plasma/serum and freeze
  • Transport to laboratory as soon as possible

Reasons for Rejection

  • Collected in tube with gel separator
  • Wrong collection tube
  • Not received at proper temperature
  • Not frozen within specified time frame


If ordered as a follow-up to a failed newborn screen, a copy of the state newborn sceening results should be submitted with the specimen.

CPT Code

  • 83921