New Search

Laboratory Test Directory

Lysosomal Enzyme Screen

Components

Name Method Department Units
Lysosomal Enzyme Screen Enzymatic assay
Send Out

Battery Members

Enzyme Activity Tested: Beta-Galactosidase, Beta-mannosidase, alpha-L-fucosidase, alpha-mannosidase, Beta-glucuronidase, Beta-hexosaminidase A, Arylsulfatase A, Galactocerebrosidase, Sphingomyelinase, Glucocerebrosidase, Alpha-L-iduronidase, Sialidase, Arylsulfatase B, Alpha-galactosidase, Alpha-glucosaminidase, Beta-hexosaminidase (Total and %A)

Specimen Requirements

Whole blood

Container Type Container Size Specimen Volume
Preferred

Green tube (Sodium heparin), No Gel

6 mL 6 mL
Alternate

Purple tube (EDTA)

6 mL 6 mL
Alternate

Green tube (Lithium heparin), No Gel

6 mL 6 mL
Alternate

Green tube (Lithium heparin), No Gel

Micro sample tube 6 mL
Stability

Room temperature - 24 hour(s)

Specimen Preparation

  • Mix heparin tube by gentle inversion immediately after collection
  • Keep at room temperature
  • Transport to laboratory as soon as possible

Reasons for Rejection

  • Collected in tube with gel separator
  • Wrong collection tube
  • Refrigerated specimen
  • Centrifuged specimen
  • Not received within specified time frame
  • Specimen received on wrong day of week.

Comments

Collect sample Monday-Thursday ONLY. It is best to have the sample in the Sendout lab no later than 6 pm on the day of the draw. The testing lab requests the samples be received at their facility within 24 hours of collection.  Sample volume less than 2 mL will not be accepted. Testing will not be performed if Clinical History Form is not submitted (see "Links" below). If single enzyme testing is requested for Krabbe (XLKRA) or MPS screening (XLMPS), please order the appropriate test code. For all other single enzyme testing, please order an XMIS.

CPT Code

  • 82657
  • 82658