New Search

Laboratory Test Directory

FISH Analysis, Specialized

Components

Name Method Department Units
FISH Analysis Only Fluorescence in situ hybridization (FISH)
Cytogenetics

Specimen Requirements

Whole blood

Container Type Container Size Specimen Volume
Preferred

Green tube (Sodium heparin), No Gel

10 mL 5 mL-10 mL
Alternate

Green tube (Sodium heparin), No Gel

3 mL 3 mL- 5 mL
Alternate

Green tube (Sodium heparin), No Gel

3 mL 1 mL-3 mL
Stability

Room temperature - 24 hour(s)

Specimen Preparation

  • Do not centrifuge
  • Do not freeze
  • Keep at room temperature

Reasons for Rejection

  • Wrong collection tube
  • Frozen specimen
  • Centrifuged specimen
  • Serum sample
  • Clotted specimen

Comments

Please click on the Lab Form Link in the Forms Section to print and complete the Genetic Test Requisition Form. Completed Genetics Test Requisition required. High resolution chromosome analysis is recommended to be done in conjunction with this testing. Specialized FISH Analysis includes centromere FISH for a specific chromosome, telomere FISH for a specific chromosome, and locus-specific FISH for examination of mosaicism, marker chromosome identification, confirmation of chromosome rearrangements (e.g. inversions, translocations, and insertions). For FISH analysis for one of the common chromosome microdeletion syndromes, such as DiGeorge syndrome or Williams syndrome, please see "FISH Analysis for Microdeletion Syndromes." Please call the Cytogeneitcs Lab at (614) 722-5321 and ask to speak to a laboratory genetic counselor before sending the specimen, as alternate testing may be recommended (e.g. microarray analysis). Please collect in Sodium Heparin tube (dark green-top tube without gel separator). Do NOT use Lithium Heparin or other types of heparin tubes; check tube for proper heparin type.

Forms

Lab Form

CPT Code

  • 88273
  • 88271
  • 88230