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Laboratory Test Directory

Creatine Kinase Isoenzymes


Name Method Department Units
Creatine Kinase Isoenzymes Quantitative Enzymatic/Electrophoresis
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Battery Members

CK-MM, CK-MB, CK-BB, Creatine Kinase, Total, CK-Macro Type I, CK-Macro Type II

Specimen Requirements

Serum Spun

Container Type Container Size Specimen Volume

Red tube, (no anticoagulant), No Gel

3 mL 1 mL

Red Tube (no anticoagulant) with Gel

3 mL 1 mL

Gold tube, (SST) with Gel

3.5 mL 1 mL

Refrigerated - 1 week(s)
Frozen - 1 month(s)

Specimen Preparation

  • Avoid repeated freeze/thaw cycles
  • Centrifuge within 1 hour, separate supernatant and freeze

Reasons for Rejection

  • Wrong collection tube
  • Wrong temperature
  • Heparinized specimens
  • Citrate specimens
  • Specimen collected in EDTA
  • Serum or Plasma received at room temperature
  • Gross hemolysis


This test will detect CK macroenzymes.

Unacceptable Conditions: Specimens preserved in citrate, EDTA, fluoride, heparin, or iodoacetate. Room temperature specimens.

CPT Code

  • 82552
  • 82550