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Laboratory Test Directory

Chromosome Analysis, Amniotic Fluid


Name Method Department Units
Amniotic Fluid, Chromosome Analysis, Standard Chromosomal analysis
Cell Culture

Specimen Requirements

Amniotic fluid

Container Type Container Size Specimen Volume

Sterile container

N/A 20 mL-35 mL

Room temperature - 24 hour(s)

Specimen Preparation

  • Do not add fixative
  • Do not centrifuge
  • Do not freeze
  • Do not refrigerate
  • Keep at room temperature

Reasons for Rejection

  • Fixed specimen
  • Centrifuged specimen
  • Frozen specimen
  • Delayed or improper handling
  • Not received within specified time frame


Submission of completed Prenatal Genetic Test Requisition Form is required. For AneuVysion FISH screen for common aneuploidies (chromosomes 13, 18, 21, X and Y), submit additional 5-10 mL amniotic fluid. For infectious disease PCR, submit 2-3 mL additional amniotic fluid. For 7-dehydrocholesterol biochemical study (Smith-Lemli-Opitz syndrome evaluation), submit additional 2-3 mL amniotic fluid. Please keep amniotic fluid sample at room temperature and send to the laboratory within 24 hours from collection time.

CPT Code

  • 88235
  • 88267
  • 88280