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Laboratory Test Directory

Acylcarnitine Profile

Components

Name Method Department Units
Acylcarnitine Profile Tandem Mass Spectrometry (MS/MS)
Core Lab, Metabolic chemistry umol/L

Specimen Requirements

Plasma Spun, Serum Spun

Container Type Container Size Specimen Volume
Preferred

Green tube (Lithium heparin), No Gel

3 mL 1 mL
Alternate

Green tube (Lithium heparin), No Gel

Micro sample tube 1 mL
Alternate

Red tube, (no anticoagulant), No Gel

3 mL 1 mL
Alternate

Red tube, (no anticoagulant), No Gel

Micro sample tube 1 mL
Stability

Refrigerated - 4 hour(s)
Frozen - Indefinite week(s)

Specimen Preparation

  • Transport to laboratory as soon as possible
  • Centrifuge, remove plasma/serum and freeze

Blood filter card

Container Type Container Size Specimen Volume
Alternate

Blood filter paper card

N/A
Stability

Room temperature - Indefinite week(s)

Specimen Preparation

  • Transport to laboratory as soon as possible

Reasons for Rejection

  • Wrong collection tube
  • Collected in tube with gel separator
  • Inadequate filling of circles on filter paper card
  • Specimen submitted on Ohio Department of Health Newborn screen cards
  • Not received at proper temperature
  • Not received within specified time frame
  • Urine

Comments

Used to aid in the diagnosis of fatty acid and branched chain amino acid metabolism defects. There are a number of appropriate indications for utilization of this test including: Follow-up for several types of abnormal newborn screening results, subsequent to an abnormal urine acid or serum amino acid profile, and where fatty acid oxidation defects are suspected based on the patient history. When ordered as a follow-up to an abnormal newborn screening test, please submit a copy of the state newborn screening results with the specimen. The profile includes both the free and total carnitine. If collecting specimen with a blood spot card, do not allow capillary tube or patient heel to touch the collection card. Allow card to air dry 3 hours before sending to laboratory. Cards are available from Laboratory Services (614-722-5477). This test has been validated for whole blood, serum, and plasma.

CPT Code

  • 82017