Hematology, Oncology and BMT Research and Innovation

Timothy Cripe

Childhood Cancer Research Team at Nationwide Children’s Awarded $10.2 Million Moonshot Grant

The National Cancer Institute has awarded a Cancer Moonshot grant to Timothy Cripe, MD, PhD, chief of the division of Hematology, Oncology & BMT and Elaine Mardis, PhD, co-executive director of the Steve and Cindy Rasmussen Institute for Genomic Medicine at Nationwide Children's Hospital.

Ohio State, Nationwide Children's Hospital First to Offer 'Flash' Proton Therapy

A highly targeted form of proton therapy – known as “FLASH” – will be investigated in clinical trial participants with certain newly diagnosed, recurrent or advanced cancers as part of central Ohio’s first and only proton therapy center, a collaborative effort of The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) and Nationwide Children’s Hospital.

Limb-Girdle Muscular Dystrophy Type 2E

Understanding the Role of LSD2 in the Molecular Genetics of Ewing Sarcoma

Study reveals novel potential drug target for Ewing sarcoma.

Genomics

Profile of a Cancer: Getting to Know Ewing Sarcoma

Understanding how to fight a deadly enemy requires knowledge of its back story, its habits, where it hangs out and how it behaves under pressure. Ewing sarcoma has been called in for questioning.

Natural Killer Cells

A Novel Role for TGFβ in Boosting Anti-tumor Functions of Natural Killer Cells

NK cells are an important part of the strategy to manipulate the immune system to fight cancer. Making TGFβ-resistant NK cells is a step toward improving their activity against it.

Region’s First Proton Therapy Facility to Treat Cancer Patients

The Ohio State University Wexner Medical Center and the Arthur G. James Cancer Hospital and Richard J. Solove Research Institute are collaborating with Nationwide Children’s Hospital to bring the first proton therapy treatment facility to central Ohio. This will offer state-of-the-art radiation oncology treatment for adult and pediatric cancer patients in one place.

Image of an adolescent boy

A Multimodal Treatment Approach Produces Excellent Outcomes in Pediatric Paget-Schroetter Syndrome

Anticoagulation and decompressive rib-resection surgery together allow young patients to return to normal activity, however the utility of thrombolysis for this condition remains unclear.