Childhood Cancer Research Team at Nationwide Children’s Awarded $10.2 Million Moonshot Grant
The National Cancer Institute has awarded a Cancer Moonshot grant to Timothy Cripe, MD, PhD, chief of the division of Hematology, Oncology & BMT and Elaine Mardis, PhD, co-executive director of the Steve and Cindy Rasmussen Institute for Genomic Medicine at Nationwide Children's Hospital.
A highly targeted form of proton therapy – known as “FLASH” – will be investigated in clinical trial participants with certain newly diagnosed, recurrent or advanced cancers as part of central Ohio’s first and only proton therapy center, a collaborative effort of The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) and Nationwide Children’s Hospital.
Study reveals novel potential drug target for Ewing sarcoma.
Understanding how to fight a deadly enemy requires knowledge of its back story, its habits, where it hangs out and how it behaves under pressure. Ewing sarcoma has been called in for questioning.
NK cells are an important part of the strategy to manipulate the immune system to fight cancer. Making TGFβ-resistant NK cells is a step toward improving their activity against it.
The Ohio State University Wexner Medical Center and the Arthur G. James Cancer Hospital and Richard J. Solove Research Institute are collaborating with Nationwide Children’s Hospital to bring the first proton therapy treatment facility to central Ohio. This will offer state-of-the-art radiation oncology treatment for adult and pediatric cancer patients in one place.
Anticoagulation and decompressive rib-resection surgery together allow young patients to return to normal activity, however the utility of thrombolysis for this condition remains unclear.
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