Hematology, Oncology and BMT Research and Innovation

CLABSI in Hematology and Oncology: Progress Toward Zero

A thorough review of five years of CLABSI data reveals key gaps in clinical knowledge that must be addressed to further reduce infection rates.

Green and Orange pills

Can Smartphone Apps Keep AYA Oncology Patients Plugged in to Their Medication Routines?

Studies show that suboptimal medication adherence may be a barrier to increased survival rates among adolescents and young adults with cancer. Anthony Audino, MD, explores the utility of medication adherence apps to meet the unique needs of these patients.

Hemalatha Rangarajan, MD

Novel Adjuvant Therapy Resolves Steroid-Refractory Acute Graft-Versus-Host Disease in a Pediatric Transplant Recipient

Physicians have successfully treated steroid-refractory gastrointestinal acute graft-versus-host disease with the monoclonal antibody vedolizumab in a pediatric allogeneic hematopoietic cell transplant recipient.

Natural Killer Cells

From Natural Killer Cells to Virus-Specific T Cells: What’s Next in Cellular Therapy

Harnessing the power of the immune system to overcome cancer, improve outcomes of bone marrow transplants and fight viral infections in immunocompromised pediatric patients is at the heart of cell therapy research.

Pediatrics Nationwide

Targeting Alternative RNA Splicing in Pediatric Cancers

Targeting alternative RNA splicing in tumor cells could lead to cancer therapies.

Ohio State, Nationwide Children's Hospital First to Offer 'Flash' Proton Therapy

A highly targeted form of proton therapy – known as “FLASH” – will be investigated in clinical trial participants with certain newly diagnosed, recurrent or advanced cancers as part of central Ohio’s first and only proton therapy center, a collaborative effort of The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) and Nationwide Children’s Hospital.

Limb-Girdle Muscular Dystrophy Type 2E

Understanding the Role of LSD2 in the Molecular Genetics of Ewing Sarcoma

Study reveals novel potential drug target for Ewing sarcoma.