The Heart Center Research and Innovation

Transplant-Free Survival Among Children With Hypoplastic Left Heart Syndrome Undergoing Hybrid Palliation

The first long-term evaluation of kids with hypoplastic left heart syndrome undergoing hybrid palliation procedures finds transplant-free survival similar to that of the standard treatment at age 15 years.

Heart tissue engineering

Findings Show TEVG Stenosis Spontaneously Resolves

The complication that halted a clinical trial for tissue-engineered vascular grafts for children with congenital heart disease may reverse spontaneously without clinical complications.

Curtis J. Daniels, MD

CMS Approves New Code for ACHD Subspecialty

The official billing code will enable growth of the subspecialty and is expected to result in improved patient care.

Pediatrics Nationwide COVID and CHD

COVID-19 in Children With Congenital Heart Disease

Data are still emerging, but COVID-19 – and the subsequent inflammatory syndrome sometimes seen in children – could have serious cardiac impacts.

Congenital Heart

Study Supports Expanded Use of Ventricular Assist Devices in Children With Complex Congenital Heart Disease

New multicenter study shows that the HeartMate3 ventricular assist device is associated with low morbidity and adverse events in pediatric patients with complex CHD.

Photo of pregnant woman

For Some Fetuses With HLHS, One Follow-up Echocardiogram May Be Enough

Study suggests a low-risk subpopulation does not develop worsening heart conditions after initial test.

NICU nurse with baby

When is Palliative Care Right for Families of Children With Single Ventricle Congenital Heart Defects?

Practitioners suggest involving a palliative care team early after diagnosis.

Additional Research

The Heart in Neuromuscular Disease

Heart problems have been reported in nearly all the neuromuscular disorders. They are particularly common and serious in Duchenne and Becker muscular dystrophies.

Adult Congenital Heart Disease Research

Faculty at Nationwide Children’s Hospital are focused on evaluating and customizing treatments for adults with congenital heart disease in order to improve clinical outcomes for these patients.

Cardiovascular Development Research

Investigators at Nationwide Children’s Hospital are focused on understanding the molecular pathways that regulate normal and abnormal heart development.

Genetics of Congenital Heart Disease Research

Faculty members at Nationwide Children’s Hospital are working to understand the genetic basis of congenital heart disease and are investigating how genetic and environmental factors play a role in the development of heart defects in children.

Surgical Palliation and Device-Based Therapies Research

The Heart Center faculty members continue to investigate new surgical treatment options and ways to improve surgical outcomes.

Look Inside the Center for Regenerative Medicine

Christopher Breuer, MD, discusses the research being done in the Center for Regenerative Medicine at Nationwide Children's Hospital. Dr. Breuer and his team are working on a tissue engineered heart valve and a tissue engineered vascular graft that grows with the patient.