March

How Does Secondhand Smoke Exposure Harm Children With Cystic Fibrosis?

Altered immune and inflammatory responses hinder clearance of bacterial infections Secondhand smoke exposure appears to alter intracellular messengers, primarily prostaglandins, and the expression of inflammation genes in the blood of young children with cystic fibrosis (CF), impairing their

Surrogate Gene Therapy Protects Heart Muscle in Model of DMD

Treatment also maintains function of skeletal muscle, providing a tandem of desired impacts A gene therapy developed at Nationwide Children’s Hospital appears to protect against heart damage in mouse models of Duchenne muscular dystrophy (DMD).

Recent Publications

Khan N, Eliopoulos H, Han L, Kinane TB, Lowes LP, Mendell JR, Gordish-Dressman H, Henricson EK, McDonald M; Eteplirsen Investigators and the CINRG DNHS investigators. Eteplirsen Treatment Attenuates Respiratory Decline in Ambulatory and Non Ambulatory Patients with Duchenne Muscular Dystrophy.