NIH Awards $25 Million Research Grant to CCTS

The National Institutes of Health (NIH) has awarded a $25 million Clinical and Translational Science Award to the Center for Clinical and Translational Science (CCTS), a collaboration among The Ohio State University College of Medicine, other colleges at Ohio State and Nationwide Children’s Hospital.

This is the center’s third five-year cycle of funding from the NIH since 2008. The money will further the center’s mission of translating scientific discoveries into clinical therapies.

The CCTS provides financial, organizational and educational support to biomedical researchers, as well as opportunities for community members to participate in valuable research. Over the past 10 years, research funded by the CCTS has been published more than 1,400 times and cited on more than 55,000 occasions. In addition, CCTS researchers have completed 18 patent filings and disclosed 25 inventions.

Last year alone, funding from CCTS supported nearly a dozen Nationwide Children’s research projects. They include studies of:

  • Epigenetics of pediatric solid tumors
  • A virtual reality-based assessment tool for aiding physicians' and therapists' evaluation of pediatric TBI patients' executive functions performance
  • A screening tool to identify which children with epilepsy should receive a clinical referral for a neuropsychological evaluation
  • Ways to tailor a nutritional intervention already established for adult cancer survivors to a population of childhood cancer survivors
  • User feedback aimed at helping develop a web-based application that allows children with chronic diseases to monitor autonomously their symptom experience
  • Family impact and caregiver burden on mothers who have sons with Duchenne Muscular Dystrophy, with the eventual goal of examining emotional and physical health outcomes
  • The efficacy of a modified skin-testing device, used to detect allergies, on patients aged 12-65.

This new grant will support team science initiatives, workforce development and partnerships with private and public organizations. The funding will also continue to support core resources shared by CCTS members, including BRANCH, the Biospecimen Core Resource, Biopathology Center, Biobehavioral Outcomes Core and Research Information Solutions and Innovation.

The CCTS currently partners with local communities to improve health outcomes in areas such as mental health, substance abuse, infant mortality and obesity. The CTSA Program comprises an innovative national network of medical research institutions that work together to improve the translational research process.