Medical Professional Publications

Studying Cognitive Development in Toddlers Born Preterm

Drs. Keim and Rogers conduct the Omega Tots Study to determine if a dietary supplement can positively affect cognitive development in toddlers born preterm

Sarah Keim, PhD, principal investigator in the Center for Biobehavioral Health is conducting the Omega Tots Study, a clinical trial of a dietary polyunsaturated fatty acid supplement, similar to what is currently added to infant formula, to see if giving it to toddlers who were born preterm helps their cognitive development, as some previous studies have shown.  Children who are born preterm are at increased risk for developmental delays and learning disabilities. Early interventions are important.  Lynette Rogers, PhD, Center for Perinatal Research, is a co-investigator on the project.  Drs. Keim and Rogers received a two-year grant from the Allen Foundation for this study earlier this year.  They are planning to enroll 112 children who were former patients in one of the Nationwide Children’s Hosptial NICU’s or at other hospitals in central Ohio.  They will use the data from this small trial to apply for funding for a full-scale trial sometime in 2013.

Contact: Sarah Keim

Related publications:
Keim SA, Daniels JL, Siega-Riz AM, Herring AH, Dole N, Scheidt PC. Breastfeeding and long-chain polyunsaturated fatty acid intake in the first 4 post-natal months and infant cognitive development: an observational study. Maternal  Child Nutrition. 2012 Oct;8(4):471-82. Epub 2011 May 27. PMID: 21615865

Keim SA, Pruitt NT. Gestational weight gain and child cognitive development. International  Journal of  Epidemiology. 2012 Apr;41(2):414-22. Epub 2012 Feb 7. PMID: 22314966

Valentine CJ, Morrow G, Pennell M, Morrow AL, Hodge A, Haban-Bartz A, Collins K, Rogers LK. Randomized Controlled Trial of Docosahexaenoic Acid Supplementation in Midwestern U.S. Human Milk Donors. Breastfeeding Medicine. 2012 May 8. [Epub ahead of print] PMID: 22568471

myChildren’s mobile app

iPhone and Android.

Download Today! »

Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000