Medical Professional Publications

Research Now: Yeates Receives $3M to Work on Predicting Outcomes in Children with Mild Traumatic Brain Injury

Dr. Keith O. Yeates has received an R01 grant (HD076885) for “Predicting Outcomes in Children with Mild Traumatic Brain Injury” from the National Institute of Child Health and Human Development. The grant builds directly on his previous R01 grant (HD039834), “Postconcussive Symptoms in Children with Mild Head Injury.”

The overall goal of the new study will be to examine the prediction of persistent postconcussive symptoms and functional impairments in children and adolescents with mild traumatic brain injury (TBI) using diagnostic methods commonly employed in clinical settings. These methods include acute signs/symptoms in emergency departments, simple assessments of mental status and balance, neurocognitive testing, and neuroimaging with MRI.

The aim is to see whether these tools can help us to predict the risk for poor outcomes and to thereby stratify children in terms of their needs for closer follow up and intervention. The long term goal would be to develop prediction rules using the simplest and least expensive tools to determine which children warrant closer attention after concussion/mild TBI.

The study is expected to have a major impact on clinical practice, particularly in emergency department settings, by helping to improve prognostic determinations and focus treatment efforts for children with mild TBI.

Related publications:

Yeates KO, Kaizar E, Rusin J, Bangert B, Dietrich A, Nuss K, Wright M, Taylor HG. Reliable change in post-concussive symptoms and its functional consequences among children with mild traumatic brain injury. Archives of Pediatrics & Adolescent Medicine. 2012 Jul 1, 166(7):615-22.

Taylor HG, Dietrich A, Nuss K, Wright M, Rusin J, Bangert B, Minich N, Yeates KO. Post-Concussive Symptoms in Children with Mild Traumatic Brain Injury. Neuropsychology. 2010 Mar, 24(2): 148–159.

Grant Number: 1 R01 HD076885-01
Principal Investigator: YEATES, KEITH O
Project Title: Predicting Outcomes in Children with Mild Traumatic Brain Injury
Institution: The Research Institute at Nationwide Children's Hospital
Award Issue Date: 08/23/2013

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