Medical Professional Publications

Innovation and Discovery

(From the November 2015 Issue of MedStat)

More news from The Research Institute can be found at

Delayed Umbilical Cord Clamping May Benefit Some High-Risk Newborns

Research over the past 15 years has shown that, especially for preterm babies, waiting 30 seconds or more to clamp the umbilical cord with the infant held below the placenta is associated with higher red blood cell volume, decreased risk of intraventricular hemorrhage and decreased need for blood transfusion. Now, recent pilot studies led by Carl H. Backes, Jr., MD, a neonatologist and cardiologist at Nationwide Children’s, have demonstrated that delayed clamping is safe, feasible and beneficial for babies born 22 to 27 weeks gestational age and babies born with congenital heart disease. These studies were published online in the Journal of Perinatology in July and September.

Read the Pediatrics Nationwide article.

Vitamin D Supplementation Increases Frequency of Partial Clinical Remission for Type 1 Diabetes

Patients newly diagnosed with type 1 diabetes may have a “honeymoon” period of partial clinical remission (PCR), during which insulin secretion normalizes and the body’s systemic inflammatory response diminishes. Kathryn Obrynba, MD, an endocrinologist at Nationwide Children’s, is the lead researcher of a pilot study presented in June at the American Diabetes Association’s 75th Scientific Sessions that found vitamin D supplementation increased the frequency of PCR in children and adolescents with new onset type 1 diabetes, although larger studies are needed to reach clearer conclusions.

Read the PediatricsOnline article

Study Shows First Evidence of Association between Childhood Kidney Stones and Atherosclerosis

Kidney stones in children are increasingly common, and until recently they were believed to be an isolated medical problem. A study published in The Journal of Pediatrics is the first to examine and identify a significant association between kidney stones in children and thickened or hardened arteries, which are precursors to a wide variety of cardiovascular diseases. Kirsten Kusumi, MD, a principal investigator in the Center for Clinical and Translational Medicine at The Research Institute at Nationwide Children’s Hospital and a nephrology fellow, was lead author of the paper, and Andrew Schwaderer, MD, also a principal investigator in the Center for Clinical and Translational Medicine and research director of Nephrology at Nationwide Children’s, was senior author on the publication.

Read the news release article.

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