Gastroenterology Research Advances and Innovation :: Nationwide Children's Hospital

Gastroenterology, Hepatology and Nutrition Research and Innovation

Many children and adolescents with GI disorders have painful and often embarrassing symptoms while others endure debilitating conditions that threaten their life and their way of living. Although some therapies provide temporary relief, long-term solutions often remain merely a hope.

Pediatric GI research is vital, as gastrointestinal disorders are very common among children, have a tremendous impact on the quality of life of affected patients and their families, and have enormous financial cost.

In addition to outstanding clinical care, GI research is also a priority at Nationwide Children’s. Clinicians and scientists currently receive more than $5 million annually in external funding to perform gastrointestinal research.

Clinical Studies

Clinical researchers at Nationwide Children's are committed to identifying new approaches for the prevention, diagnosis and treatment of childhood diseases, taking research discoveries from the lab to the patient's bedside.

Browse current research studies being conducted at Nationwide Children’s related to Gastroenterology, Hepatology and Nutrition

GI Research Areas of Focus

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Pancreatitis Patients Go Home Sooner When They Direct Nutrition Decisions
Children with acute pancreatitis who led the decision to eat again had shorter hospital stays and earlier food reintroduction compared to those who awaited clinician approval.

A Better Non-Invasive Method To Monitor Liver Disease in Short Bowel Syndrome?
A pilot study suggests ultrasound elastography can be useful in determining degree of liver fibrosis in children with SBS.

New Liver Center Expands Transplant Services
Alexander Weymann, MD, and Monique L. Goldschmidt, MD, join Nationwide Children’s, enhancing hepatology and liver transplant services.

Predicting Esophageal Eosinophilia Using Serum IgE Antibody Results
Researchers can predict the presence of esophageal eosinophils — even in children with nonspecific gastrointestinal symptoms — using food-specific IgE test results and a simple new algorithm.

Sacral Nerve Stimulation Proves an Effective and Long-lasting Treatment for Children With Constipation and Fecal Incontinence
A recent study indicates that the therapy is a viable alternative for children with defecation disorders.

The First Consensus Guidelines for Evaluation of Pediatric Pancreatitis
An increasing incidence of these conditions in children has driven the creation of a first-of-its kind consensus from an international group of pediatric gastroenterologists.

The Long-Term Benefit of Behavioral Intervention for Rumination Syndrome
One year or more after undergoing intensive, inpatient behavioral treatment, adolescents reported continuing improvement in symptoms and quality of life.

Race Differences in Crohn’s Disease
Black children with Crohn’s may have more severe disease than their white peers.

Number of Children Hospitalized for Gastroparesis Rising Sharply, Along with Overall Costs
Admissions for dyspepsia and unspecified functional disorder of the stomach are also climbing, emphasizing the need for cost-effective tests and treatments

Diagnostic Testing for Rumination Syndrome is Frequent, Expensive and Often Unhelpful
The average patient in a recent study underwent almost nine tests at a cost of nearly $20,000, when diagnosis should be based on clinical symptoms and may require little or no testing.

Are Children With Celiac Disease at an Increased Risk for Functional Abdominal Pain Disorders?
Researchers find a similar prevalence of functional abdominal pain disorders in children and adolescents with celiac disease on a gluten-free diet and controls.

New Guidelines for Anorectal and Colonic Manometry in Children
The first consensus statement of its kind in 14 years — led by ANMS and endorsed by NASPGHAN — updates best practices for two common pediatric motility tests.

Meet Our GI Team

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