Mitigating Treatment-Related Toxicity in Leukemia

The multicenter Supportive Care Committee seeks to help children with relapsed or refractory leukemia avoid infections and other toxicity-related complications.

Does Feed Fortification or Blood Transfusion Quickly Lead to NEC?

A first-of-its-kind neonatal intensive care study evaluates whether feeding advances or packed red blood cell transfusions have a short-term effect on the odds of developing necrotizing enterocolitis

Differences Between Pediatric and Adult Guidelines for Classifying Left Ventricular Dilation

More than half of adolescent and young adult echocardiograms classified as abnormal by adult standards would be considered normal by pediatric standards.

Which GERD Symptoms in NICU Babies Actually Need Treatment?

Researchers gain further insight into which gastroesophageal reflux disease symptoms merit the use of proton pump inhibitors and follow-up in NICU babies with dysphagia.

Indomethacin Prophylaxis Associated With Substantially Improved Survival in Extremely Preterm Babies

While influential studies conducted in the 1990s showed no mortality benefit, a more contemporary cohort demonstrates the relative risk of death was 48 percent less for babies who received prophylaxis.

Predicting Esophageal Eosinophilia Using Serum IgE Antibody Results

Researchers can predict the presence of esophageal eosinophils — even in children with nonspecific gastrointestinal symptoms — using food-specific IgE test results and a simple new algorithm.

Examining the Modern Balloon Aortic Valvuloplasty

While safe and effective for many patients with congenital aortic stenosis, some appear to be at higher risk for complications.

Sacral Nerve Stimulation Proves an Effective and Long-lasting Treatment for Children With Constipation and Fecal Incontinence

A recent study indicates that the therapy is a viable alternative for children with defecation disorders.

A Pioneering Spine Biomechanics Lab for Children

Discovering the forces on the pediatric spine could change approaches to scoliosis surgery and other treatments.

New Targets for Nephrotic Syndrome Treatment?

Discoveries about the mechanisms of podocyte injury may lead to treatments not previously considered.

The First Consensus Guidelines for Evaluation of Pediatric Pancreatitis

An increasing incidence of these conditions in children has driven the creation of a first-of-its kind consensus from an international group of pediatric gastroenterologists.

Severe BPD Ventilator Strategies: A Quick Guide

A chart, adapted from the Bronchopulmonary Dysplasia Consortium, shows the differences in strategies between the first week of life, when prevention is the goal, and later, when severe BPD has been established.

The Long-Term Benefit of Behavioral Intervention for Rumination Syndrome

A number of publications demonstrate that behavioral treatment strategies for adolescents with rumination syndrome have short-term success.

Sleep-Disordered Breathing and Cardiovascular Issues in Children

Sleep-disordered breathing affects the heart, but cardiovascular complications can also affect sleep.

Finding Better Markers of Cardiovascular Risk in Pediatric Type 1 Diabetes

Children and adolescents with type 1 diabetes are at risk for cardiovascular disease. Are there ways to determine who is at greatest risk, and who benefits most from early intervention?