Innovation and Discovery

 (From the January 2019 Issue of MedStat)

Acid Suppression Should Not Be the First Treatment for Infants With Reflux

Studies fail to support the use of acid-suppression medications in infants with gastroesophageal reflux, a data review led by Steven Ciciora, MD, director of the division of educational activities in the Division of Gastroenterology, Hepatology and Nutrition at Nationwide Children’s Hospital, found. In fact, a number of studies indicate the drugs may be associated with harmful effects in young children. New clinical guidelines emphasize use of non-pharmacologic treatments, such as thickening feeds or altering formula, and clear communication with caregivers. Learn more in this Pediatrics Online article.

New Tool Can Help Doctors Identify Child Sex Trafficking Victims

A new study found that more than one in 10 minors visiting emergency departments, child advocacy centers and teen clinics for sexual trauma or assault are victims of child sex trafficking (CST). The research, led by Mary Jo Bowman, MD, attending physician in emergency medicine at Nationwide Children’s Hospital, used one of the first CST screening tools specifically developed and evaluated in a healthcare setting. The researchers hope to expand use of the tool to other providers, particularly to address children with behavioral or mental health issues that may increase risk. Learn more in this Pediatrics Nationwide article.

Insulin Resistance May Cause More Frequent, Complex UTIs in People With Diabetes

Children and adults with diabetes suffer more frequent and complex urinary tract infections compared to the general population. Excess glucose in the urine has long been considered the cause, but new research led by John David Spencer, MD, a nephrologist and principal investigator in the Center for Clinical and Translational Research at Nationwide Children’s Hospital, indicates that may not be the case. The researchers show that insulin resistance results in a lowering of natural defenses and suggest resistance alone or in combination with excess glucose lead to susceptibility. Learn more in this Research Now article.