Neuromuscular Genetic Therapeutics Fellowship Curriculum

Clinical Experiences

The training program consists of a two year fellowship, with an expectation for participation throughout in research.  Research options include both clinical and basic research project, including work in laboratories within the Center of Gene Therapy and in collaborating laboratories on the Ohio State University campus. 

The clinical experience will include three clinics per week, including a Muscular Dystrophy Association clinic with an emphasis on (but not limited to) pediatric disorders; an adult neuromuscular disease clinic, concentrating on inherited muscle diseases and myopathies; and a pediatric motor neuron disease clinic, concentrating on spinal muscular atrophy.

Given the emphasis of our Center for Gene Therapy on muscle disease, the fellowship will include education in neuromuscular pathology.  The Nationwide Children's Neuromuscular Pathology Core, directed by Dr. Zarife Sahenk, provides pathologic diagnoses for over 150 cases per year.  Fellows will have a primary role in interpreting neuromuscular pathology, and will take part in the weekly neuromuscular pathology conference with members of the neuromuscular pathology center and with neuropathology staff.

Didactic Conferences

Additional didactic training will include the following conferences:

  • Bi-weekly Muscle Biology and Disease journal club (K. Flanigan and Dr. Scott Q. Harper, directors), covering all aspects of genetic therapeutics. 

  • Weekly neuromuscular pathology review (Z. Sahenk, director).

  • Monthly meetings of the OSU/NCH Muscle Group.

  • Quarterly seminars given by nationally and internationally recognized speakers as part of Nationwide Children's NIH-funded Sen. Paul Wellstone Muscular Dystrophy Clinical Research Center.

  • Weekly seminar series hosted by the the Research Institute at Nationwide Children's.

  • Participate in a basic laboratory techniques course over a two-month period within the first year.  

Addtional Training

All trainees will also:

  • Receive training in Human Subjects research through the resources made available by the Nationwide Children's IRB and Clinical Research Services division.

  • Participate in the Nationwide Children's Research Institute’s Grant Writing seminars.

  • Participate in the Trainee Poster Day of the OSU/NCH Muscle Group.

  • Participate in all educational activities and seminars of the Nationwide Children's Wellstone Muscular Dystrophy Cooperative Research Center, one of six such U54-funded centers in the United States.