Jennifer K Trittmann, MD, MPH
Contact Information
Jennifer Trittmann, MD, MPH, is Principal Investigator, Center for Perinatal Research, Abigail Wexner Research Institute at Nationwide Children’s Hospital and an Assistant Professor in the Division of Neonatology, Department of Pediatrics at The Ohio State University College of Medicine. Dr. Trittmann’s research focuses on bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH), a life-threatening neonatal disease characterized by progressive pulmonary vascular endothelial dysfunction and smooth muscle cell proliferation. Currently, there are no available predictive biomarkers or curative therapies for BPD-PH. Our labs at the Abigail Wexner Research Institute have discovered genetic and biochemical markers for BPD-PH including: single polymorphisms in arginase-1 (ARG1), dimethylarginine dimethylaminohydrolase-1 (DDAH1), dual specificity phosphatase-1&5 (DUSP1&5), and plasma levels of asymmetric dimethylarginine (ADMA). Our group has developed endothelial DDAH1 conditional knockout mice for studies after intrauterine inflammation (LPS) and post-natal hyperoxia exposure, a disease model for BPD-PH.
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Center for Perinatal Research
Principal Investigator -
Neonatology
Principal Investigator -
Neonatology Fellowship
Faculty -
Primary Department
Center for Perinatal Research
- Member, NIH LRP Ambassador Program, 2017 - Present
- Member, American Thoracic Society, 2016 - Present
- Member, Ohio American Academy of Pediatrics, 2016 - Present
- Member, Nitric Oxide Society, 2016 - Present
- Member, Society for Pediatric Research, 2016 - Present
- Member, American Physiological Society, Respiratory Section, 2014 - Present
- Fellow, American Academy of Pediatrics, Neonatal-Perinatal Section, 2008 - Present
- Member, American Academy of Pediatrics, 2005 - Present
- Member, March of Dimes, 2005 - Present
Date of Appointment at Nationwide Children’s Hospital: 09/30/2011
| Fellowship | Nationwide Children's Hospital | Date Completed: 09/28/2011 |
|---|---|---|
| Graduate School | The Ohio State University | Date Completed: 06/12/2011 |
| Residency | Nationwide Children's Hospital | Date Completed: 06/30/2008 |
| Medical School | The Ohio State University | Date Completed: 06/12/2005 |
2011 - Present Nationwide Children's Hospital, Principal Investigator, Center for Perinatal Research at The Research Institute
2011 - Present The Ohio State University, Assistant Professor, College of Medicine, Department of Pediatrics
NIH NHLBI 1K08HL129080 Mentored Clinical Scientist Research Career Development Award
Novel therapeutic targets for bronchopulmonary dysplasia-associated pulmonary hypertension, Principal Investigator