Through the latest technologies available from Agilent and Affymetrix we provide powerful solutions for research in cancer and developmental disorders by enabling scientists to conduct large-scale linkage analysis, association, and copy number studies.
Agilent Oligo aCGH Platform
Microarray-based Comparative Genomic Hybridization (aCGH) is a powerful technique used to identify and characterize DNA copy number variations across the genome. Agilent’s oligonucleotide aCGH platform is an integrated solution that gives you the resolution and flexibility to perform genome-wide as well as customized zoom-in profiling of genomic aberrations on a single chip, along with simplified experimental design and ease-of-use protocols to handle genomic samples with full complexity. High (974,000 elements) and medium (244,000 elements) resolution formats are available for human, mouse and rat samples with comprehensive probe coverage spanning both coding and noncoding regions, with emphasis on well-known genes, promoters, miRNAs, and telomeric regions.
SurePrint G3 Human CGH Microarray Kit 1x1M - NEW!
The Agilent SurePrint G3 Human CGH Microarray Kit 1x1M is the next generation high-density tool for genome-wide DNA variation profiling. Comprehensive probe coverage spans coding and non-coding regions, with emphasis on known genes, promoters, miRNAs, disease pseudoautosomal, and telomeric regions. Probe design and selection have been carefully optimized and validated for maximal sensitivity and specificity. The 1x1M format has approximately four times more coverage than the legacy 244K format for better breakpoint detection and identifying novel aberrations.
Affymetrix® Whole-Genome Cytogentics 2.7M - NEW!
The Affymetrix® Cytogenetics Whole-Genome 2.7M Array provides the greatest power to detect known and novel aberrations across the entire genome. With unbiased, whole-genome coverage and the highest density of 2.7 million copy number markers, this array enables you to detect even the smallest submicroscopic aberrations, including those that would have been missed with classical techniques. It provides dense coverage of the RefSeq genes, cancer genes, miRNA regions, and haploinsufficiency genes, which are of particular relevance to cytogeneticists. In addition, the Whole-Genome 2.7M Array includes 400,000 single nucleotide polymorphisms (SNPs) that enable you to detect loss of heterozygosity (LOH), uniparental disomies (UPD), and regions of the genome that are identical-by-descent.
Affymetrix® Genome-Wide Human SNP Array 6.0
The new Affymetrix® Genome-Wide Human SNP Array 6.0 features 1.8 million genetic markers, including more than 906,600 single nucleotide polymorphisms (SNPs) and more than 946,000 probes for the detection of copy number variation (CNVs). The SNP Array 6.0 demonstrates industry-leading performance and represents more genetic variation on a single array than any other product, providing maximum panel power and the highest physical coverage of the genome.