Thomas G. Gross, MD, PhD :: Nationwide Children’s Hospital, Columbus, Ohio

Thomas G. Gross, MD, PhD

Thomas G. Gross, MD, PhD Best Doctors 2011-2012

Contact Information

Hematology / Oncology
700 Children's Dr
Columbus, OH 43205 [ map ]
PH: (614) 722-3552
FX: (614) 722-3699
E-mail Me
The Research Institute at Nationwide Children's Hospital
700 Childrens Drive
Columbus, OH 43205 [ map ]
PH: (614) 722-2700

Office Practice Information:

  • Accepts patients 0-18.
  • Accepts patients 18 years or older.
  • Accepts Medicaid.
  • Requires a written physical referral.
  • This office is wheelchair accessible.

Biography

Thomas G. Gross, MD, PhD is a member of the Division of Hematology/Oncology/BMT at Nationwide Children’s Hospital, a member of the Center of Childhood Cancer Research at Nationwide Children’s Research Institute and a Professor of Pediatrics at The Ohio State University College of Medicine. He serves on the Institutional Review Board and Clinical Research Scientific Council and is a member of the Pediatric Oncology and Viral Oncogenesis Program at the NCIdesignated Comprehensive Cancer Center at The Ohio State University. His clinical interests are BMT and the treatment of cancers in immunocompromised patients, such as post-transplant lymphoproliferative disease (PTLD). His research interests are focused on transplant and tumor immunology. He is the Principal Investigator for the PTLD clinical trial in the Children’s Oncology Group (COG), and is the Chair of the Non-Hodgkin’s Lymphoma (NHL) Disease Committee in COG. Dr. Gross is co-investigator on several NIH-funded clinical studies in transplantation and NHL. He serves on the Pediatric Cancer Editorial Board for the Physician Data Query at the National Cancer Institute, on the Board of Trustees of the National Childhood Cancer Foundation and the Board of Directors of the Israel Penn International Transplant Tumor Registry. He is a member of several committees for the Pediatric Blood and Marrow Transplant Consortium, Center for International Blood and Marrow Transplant Research, International Pediatric Transplantation Association, American Society of Transplantation, as well as scientific advisory committees for several pharmaceutical companies.

Gender:

  • Male

Languages Spoken:

  • English

Research Interests

Research Funding*:

  • The Combination of Cyclophosphamide, Prednisone and Rituximab (CPR) in Children, Adolescents and Young Adults with CD20 Positive Post-Transplant Lymphoproliferative Disease (PTLD) Following Solid Organ Transplant (SOT), National Cancer Institute
  • Consultant, SCCOR in Pediatric Heart Development and Disease. Optimizing Outcome after Pediatric Heart Transplantation, NHLBI, Principal Investigator: Steven Webber, MD (Univ. of Pittsburgh)
  • COG Non-Hodgkin Lymphoma Disease Committee Chair, National Cancer Institute
  • Consultant, Real-time Minimal Residual Disease Assay of Pediatric B-Cell Non-Hodgkin Lymphoma, National Cancer Institute, Principal Investigator: Bruce Shiramizu, MD

Education and Training

Undergraduate School

  • University of Nebraska

Medical School

  • University of Nebraska Medical Center

Post Doctoral

  • University of Nebraska Medical Center

Medical School

  • University of Nebraska Medical Center

Residency

  • University of Nebraska Medical Center

Residency

  • University of Minnesota Hospital and Clinics

Medical School

  • University of Nebraska
    Date Completed: 05/07/1988

Internship

  • University of Nebraska Medical Center
    Date Completed: 06/29/1989

Residency

  • University of Nebraska Medical Center
    Date Completed: 06/29/1991

Fellowship

  • University of Minnesota Hospitals and Clinics
    Date Completed: 08/31/1993

Department:

  • Pediatrics

Section:

  • Hematology/Oncology

Speciality:

  • Pediatric Hematology Oncology

Date of Appointment at Nationwide Children’s Hospital:

  • 11/15/2002

Professional Experience

2006–present

  • Member, Board of Trustees, National Childhood Cancer Foundation

2005–present

  • Editorial Board - PDQ® (Physician Data Query) - NCI's Comprehensive Cancer Database Pediatric Treatment 

2004–present

  • Chair, Non-Hodgkin’s Lymphoma Committee, Children’s Oncology Group

2002–present

  • Associate Professor, Department of Pediatrics, The Ohio State University Medical School, Columbus, OH

2002–present

  • Chief, Division of Hematology/Oncology,  Nationwide Children's Hospital, Columbus, OH

2001–present

  • Member, Board of Directors - Israel Penn International Transplant Tumor Registry

1998–present

  • Adjunct Assistant Professor, Department of Pathology/Microbiology, University of Nebraska Medical Center, Omaha, NE

1993–present

  • Clinical Director, XLP Study Group and David T. Purtilo International XLP Registry

1998–2002

  • Associate Professor, Division of Hematology/Oncology, Children’s Hospital Medical Center, Cincinnati OH

1998–2002

  • Director, Blood and Marrow Transplant Program, Children’s Hospital Medical Center, Cincinnati, OH

1997–1998

  • Clinical Director, Pediatric Bone Marrow Transplant Program, University of Nebraska Medical Center, Omaha NE

1993–1998

  • Assistant Professor, Departments of Pathology and Microbiology and Pediatric Hematology/Oncology and Bone Marrow Transplantation, University of Nebraska Medical Center, Omaha NE

Publications

  • Gross TG; Savoldo B; Punnett A. 2010. Posttransplant lymphoproliferative diseases.  Pediatric Clinics Of North America. Vol. 57, no. 2. (April): e481.
  • Gross TG; Hale GA; He W; Camitta BM; Sanders JE; Cairo MS; Hayashi RJ; Termuhlen AM; Zhang MJ; Davies SM; Eapen M. 2010. Hematopoietic stem cell transplantation for refractory or recurrent non-Hodgkin lymphoma in children and adolescents.  Biology Of Blood And Marrow Transplantation: Journal Of The American Society For Blood And Marrow Transplantation. Vol. 16, no. 2. (February): e223.
  • Smith AR; Gross TG; Baker KS. 2010. Transplant outcomes for primary immunodeficiency disease.  Seminars In Hematology. Vol. 47, no. 1. (January): e79.
  • Harris RE, Termuhlen AM, Henry MM, Perkins SL, Gross TG, Warkentin PI, Vlachos A, Lynch J, Harrison L, Cairo MS. 2010. Safety and efficacy of cyclophosphamide, carmustine, and etoposide (CBV) followed by autologous peripheral blood stem cell (PBSC) transplant in children with lymphoma after induction failure or first relapse – A Children’s Oncology Group study.  Biol Blood Marrow Transpl.
  • Wang M, Gross TG. 2010. Molecular targeting of post-transplant lymphoproliferative disorders. In Molecularly Targeted Therapy for Childhood Cancer. Edited by Houghton PJ and Arceci RJ. New York, NY: Springer Science+Business Media, LLC.
  • Klopfenstein K, Rosselet R, Clayton J, Kerlin B, Termuhlen A, Gross T. 2009. Prevalence of abnormal bone mineral density in pediatric patients prior to blood and marrow transplant.  Pediatr Blood Cancer.
  • Lagmay JP, London W, Gross TG, Termuhlen A, Sullivan N, Ranalli M, Canner J, Axel1 A, Mundy B, McGrady P, Hall B. 2009. Prognostic significance of interleukin-6 single nucleotide polymorphism genotypes in neuroblastoma: rs1800795 (promoter) and rs8192284 (receptor) .  Clin Cancer Res.
  • Lagmay JP; London WB; Gross TG; Termuhlen A; Sullivan N; Axel A; Mundy B; Ranalli M; Canner J; McGrady P; Hall B. 2009. Prognostic significance of interleukin-6 single nucleotide polymorphism genotypes in neuroblastoma: rs1800795 (promoter) and rs8192284 (receptor).  Clinical Cancer Research: An Official Journal Of The American Association For Cancer Research. Vol. 15, no. 16. (August): e5234.
  • Lowe EJ; Sposto R; Perkins SL; Gross TG; Finlay J; Zwick D; Abromowitch M. 2009. Intensive chemotherapy for systemic anaplastic large cell lymphoma in children and adolescents: final results of Children's Cancer Group Study 5941.  Pediatric Blood & Cancer. Vol. 52, no. 3. (March): e335.
  • Gross TG. 2009. Chronic active Epstein-Barr virus--is it real and how do you treat it?.  Pediatric Transplantation. Vol. 13, no. 2. (March): e146.
  • Cairo MS, Gross TG. 2009. Non-Hodgkin's lymphoma. In Rudolph's Peditrics. 22nd ed. Edited by Rudolph AM, Rudolph C, First L, et al. New York, NY: McGraw Hill.
  • Lowe EJ, Sposto R, Perkins SL, Gross TG, Finlay J, Wienstein H, Abromowitch M. 2009. Intensive, compressed chemotherapy for non-localized anaplastic large cell lymphoma in children and adolescents: A Children's Cancer Group study.  Pediatr Blood Cancer.. Vol. 53, no. January: 335-339.
  • Gross TG, Hale GA, Ho V, Camitta BM, Sanders JE, Cairo MS, Hayashi RJ, Termuhlen AM, Davies SM, Eapen M. 2009. Hematopoietic stem cell transplantation as salvage therapy for non-Hodgkin lymphoma in children and adolescents: a report from the Center for International BLood and Marrow Transplantation Research.  Biology of Blood and Marrow Transplantation.
  • Gross TG, Porcu P, Baiocchi RA. 2009. Non-Hodgkin lymphoma in immunodeficient hosts. In Non-Hodgkin Lymphomas. 2nd ed. Edited by Mauch PM, Armitage JO, Coiffier B, et al. Philadelphia, PA: Lippincott Williams & Wilkins.
  • Gross TG. 2009. Infectious Mononucleosis and other EBV-related disroders. In Wintrobe's Clinical Hematology. 12th ed. Edited by Greer JP, Foerster J, Lukens JN et al. Philadelphia, PA: Lippincott Williams & Wilkins.
  • Gross TG. 2009. Stephen J. Qualman, MD (1953-2008) (Obituary).  Pediatric Blood and Cancer.
  • Buell JF, Gross TG, Woodle ES, Webster AC, Chapman JR. 2009. Current concepts in post-transplant lymphoproliferative disorder (PTLD).  Lancet Nephrology.
  • Gross TG. 2009. PTLD following hematopoietic stem cell transplantation. In Post-transplant Lymphoproliferative Disorders (PTLD). 1st ed. Edited by Dharnidharka V, Green M, Webber S. New York, NY: Springer Publishing.
  • Gross TG. 2009. Chronic active Epstein-Barr virus - Is it real and how do you treat it?.  Pediatr Transplant..
  • Gross TG, Perkins SL. 2009. Malignant Non-Hodgkin lymphoma in children. In Principles and Practice of Pediatric Oncology. 6th ed. Edited by Pizzo PA and Poplack DG. Philadelphia, PA: Lippincott Williams and Wilkins.
  • Gross TG. 2009. Treatment of Epstein-Barr virus associated post-transplant lymphoproliferative disease.  Herpes.
  • Griffin TC, Weitzman S, Weinstein H, Chang M, Cairo MS, Hutchison R, Shiramizu B, Wiley J, Woods D, Barnich M, Gross TG. 2009. A study of rituximab and ifosamide, carboplatin and etoposide chemotherapy in children with recurrent/refractory B-cell (CD20+) non-Hodgkin lymphoma and mature B-cell acute lymphoblastic leukemia. A Children's Oncology Group study.  Pediatric Blood and Cancer.
  • Cairo MS, Gross TG. 2009. Hematopoietic stem cell transplantation in the management of pediatric malignancies.  Cancer Treat Res. Vol. 144, no. January: 1-42.
  • Miao Y, EverlyJJ, Gross TG, Tevar A, First MR, Alloway RR, Woodle ES. 2009. De novo cancers arising in the organ transplant recipients are associated with adverse outcomes compared to the general population.  Transplantation. Vol. 87, no. January: 1347-1359.
  • Mustillo P, Bajwa RP, Termuhlen AM, Nicol K, Scherzer R, Jaffe R, Filipovich AH, Gross TG. 2008. Tumor immune surveillance defect of X-linked severe combined immunodeficiency is not Epstein-Barr virus specific.  Pediatr Blood Cancer.. Vol. 51, no. 5. (November): 706-709.
  • Baker KS, Filipovich AH, Gross TG, Grossman WJ, Hale GA, Hayashi RJ, Kamani NR, Kurian S, Kapoor N, Ringdén O, Eapen M. 2008. Unrelated donor hematopoietic cell transplantation for hemophagocytic lymphohistiocytosis.  Bone Marrow Transplant. Vol. 42, no. 3. (August): 175-180.
  • Rose MJ, Nicol KK, Skeens MA, Gross TG, Kerlin BA. 2008. Congenital amegakaryocytic thrombocytopenia: the diagnostic importance of combining pathology with molecular genetics.  Pediatr Blood Cancer.. Vol. 50, no. 6. (June): 1263-1265.
  • Guthery SL, Gross TG. 2008. Assessing the risk of epstein-barr virus-related lymphoproliferative disorders before administration of visilizumab.  Gastroenterology.. Vol. 134, no. 3. (March): 895-896.
  • Ozkaynak MF, Sahdev I, Gross TG, Levine JE, Cheerva AC, Richards MK, Rozans MK, Shaw PJ, Kadota RP. 2008. A pilot study of addition of amifostine to melphalan, carboplatin, etoposide, and cyclophosphamide with autologous hematopoietic stem cell transplantation in pediatric solid tumors-A pediatric blood and marrow transplant consortium study.  J Pediatr Hematol Oncol.. Vol. 30, no. 3. (March): 204-209.
  • O'Brien D, Klopfenstein K, Gross TG, Baker P, Termuhlen A. 2008. Spongiform encephalopathy following allogeneic cord blood transplant.  Pediatr Transplant.. Vol. 12, no. 1. (February): 95-98.
  • Perez-Albuerne ED, Eapen M, Klein J, Gross T, Lipton JM, Baker KS, Woolfrey A, Kamani N. 2008. Outcome of unrelated donor stem cell transplantation for children with severe aplastic anemia.  Br J Haematol. Vol. 141, no. January: 216-223.
  • Greiner TC, Gross TG. 2008. Atypical Immune Lymphoproliferations. In Hematology: Basic Principles and Practice, 5th ed. Edited by Hoffman, et al. Philadelphia, PA: Churchill Livingstone.
  • Gross TG, Termuhlen AM. 2008. Pediatric non-Hodgkin’s lymphoma.  Curr Hematol Malign Rep. Vol. 3, no. January: 167-173.
  • Woodle ES, Gross TG, Alloway R, Tevar A, Buell J. 2008. Living donor kidney transplantation and malignancy. In Living Donor Organ Transplantation. 1st Ed.. Edited by Gruessner R, Benedetti E. New York, NY: McGraw-Hill.
  • Gros TG. 2008. Management of post-transplant lymphoproliferative disease. In Intestinal Failure, Management and Transplantation. 1st Ed.. Edited by Langnas A, Goulet O, Quigley E, et all. Oxford: Blackwell Publishing Ltd..
  • Cairo MS, Gross TG. 2008. Hematopoietic stem cell transplantation in the management of pediatric malignancies. In Hematopoietic Stem Cell Transplantation. New York, NY: Springer Publishing.
  • Gross TG. 2008. When ther are no randomized phase III trials - what is a doctor to do?.  Journal of Pediatric Hematology/Oncology.
  • Termuhlen AM, Klopfenstein K, Olshefski R, Altura R, Boyer MW, Rosselet R, Gross TG. 2008. Mobilization of PML-RARA negative blood stem cells and salvage with autologous peripheral blood stem cell transplantation in children with relapsed acute promyelocytic leukemia.  Pediatr Blood Cancer. Vol. 51, no. January: 521-524.
  • Filipovich AH, Gross TG. 2008. Immunodeficiency and cancer. In Clinical Oncology, 4th ed. Edited by Abeloff MD, et al. Portland, OR: Book News, Inc..
  • Gross TG, M Termuhlen A. 2007. Pediatric Non-Hodgkin's Lymphoma.  Current Oncology Reports. Vol. 9, no. 6. (January): 459-465.
  • Gross TG. 2007. Post-transplant lymphoproliferative disease in children following solid organ transplant and rituximab--the final answer?.  Pediatric Transplantation. Vol. 11, no. 6. (January): 575-577.
  • Rosh JR, Gross T, Mamula P, Griffiths A, Hyams J. 2007. Hepatosplenic T-cell lymphoma in adolescents and young adults with Crohn's disease: a cautionary tale?.  Inflammatory Bowel Diseases. Vol. 13, no. 8. (January): 1024-1030.
  • Hanaway MH, Buell JF, First MR, Trofe J, Beebe TM, Peddi, VR, Gross TG, Alloway R, Woodle ES. 2007. Malignancy after pancreas transplantation. In Pancreatic Transplantation. Edited by Corry RJ and Shapiro R. New York, NY: Marcel Dekker, Inc..
  • Okano M, Gross TG. 2007. Advanced therapeutic and prophylactic strategies for Epstein-Barr virus infection in immunocompromised patients.  Expert Review of Anti-Infective Therapy. Vol. 5, no. 3. (January): 403-413.
  • Gross TG, Shiramizu B. 2007. Post-transplant lymphoproliferative disorders and lymphomas related to immunodeficiency. In Pediatric Lymphoma. Edited by Weinstein H and Hudson M. New York, NY: Springer-Verlag Berlin Heidelberg.
  • Seemayer TA, Gross TG, Sumegi J. 2006. X-linked lymphoproliferative syndrome. In Epstein-Barr virus. Edited by AC Tselis, HB Jenson. New York, NY: Marcel Dekker, Inc.
  • Termuhlen AM, Grovas A, Klopfenstein K, Rosselet R, Gross TG. 2006. Autologous hematopoietic stem cell transplant with melphalan and thiotepa is safe and feasible in pediatric patients with low normalized glomerular filtration rate.  Pediatr Transplant. Vol. 10, no. January: 830-834.
  • Buell JF, Gross TG, Thomas MJ, Neff G, Muthiah C, Alloway R, Ryckman FC, Tiao GM, Woodle ES. 2006. Malignancy in pediatric transplant recipients.  Semin Pediatr Surg.. Vol. 15, no. January: 179-187.
  • Husted TL, Neff G, Thomas MJ, Gross TG, Woodle ES, Buell JF. 2006. Liver transplantation for primary or metastatic sarcoma to the liver.  Am J Transplant. Vol. 6, no. January: 392-397.
  • J, Buell JF, Beebe TM, Hanaway MJ, First MR, Alloway RR, Gross TG Woodle ES. 2005. The Israel Penn International Transplant Tumor Registry 32 year Experience with 402 Renal Transplant Recipients with Post Transplant Lymphoproliferative Disease: Multivariate Analysis of Risk Factors that Influence Survival.  Am J Transplant. Vol. 5, no. January: 775-780.
  • Buell JF, Gross TG, Hanaway MJ, Trofe J, Roy-Chaudhury P, First MR, Woodle ES. 2005. Post transplant lymphoproliferative disorder: Significance of central nervous system involvement.  Transplant Proc. Vol. 37, no. January: 954-955.
  • Buell JF, Gross TG, Woodle ES. 2005. Malignancy after transplantation.  Transplantation. Vol. 80, no. January: S254-264.
  • Lankester A, Visser L, Bredius R, Van Tol M, Hartwig N, van der Burg M, Gross TG, Gaspar HB, Egeler M. 2005. Allogeneic stem cell transplantation in X-linked lymphoproliferative disease in different stages of disease: two cases in one family and review of the literature.  Bone Marrow Transpl. Vol. 36, no. January: 99-105.
  • Buell JF, Gross T, Alloway RR, Trofe J, Woodle ES. 2005. Donor CNS Tumors:Misdiagnosis carries a high morbidity and morality.  Transplant Proc. Vol. 37, no. January: 583-584.
  • Buell JF, Gross TG, Hanaway MJ, Trofe J, Muthiak C, First RM Alloway RR, Woodle ES. 2005. Chemotherapy for PTLD: The Israel Penn International Transplant Tumor Registry Experience.  Transplant Proc. Vol. 37, no. January: 956-957.
  • Gross TG, Bucuvalas J, Park J, Greiner TC, Hinrich SH, Kaufman S, Langnas A, McDonald R, Ryckman F, Shaw B, Sudan D, Lynch JC. 2005. Low dose chemotherapy for the treatment of refractory post-transplant lymphoproliferative disease in children.  J Clin Oncol. Vol. 23, no. January: 6481-6488.
  • Woodle ES, Gupta M, Buell JF, Neff GW, Gross TG, First MR, Hanaway MJ, Trofe J. 2005. Prostate cancer prior to solid organ transplantation: The Israel Penn International Transplant Tumor Registry experience.  Transplant Proc. Vol. 37, no. January: 958-959.
  • Gross TG, Shiramizu B. 2005. Lymphoproliferative disorders and malignancies related to immunodeficiencies. In Principles and Practice of Pediatric Oncology. 5th ed. Edited by Pizzo PA and Poplack DG. Philadelphia, PA: Lippincott Williams and Wilkins.
  • Shiramizu B, Gross T, Okano M. 2005. Human Immunodeficiency Virus-Associated Non-Hodgkin Lymphoma. In Progress in AIDS Research. Edited by Liberman AP. Hauppauge, NY: Nova Science Publishers, Inc.
  • Trofe J, Buell JF, Woodle ES, Beebe TM, Sethuraman G, Hanaway MJ, First MR, Alloway RR, Gross TG. 2004. Recurrence risk following organ transplantation in patients with history of Hodgkin’s disease or non Hodgkin’s lymphoma.  Transplantation. Vol. 78, no. January: 972-977.
  • Papaconstantinou HT, Sklow B, Hanaway MJ, Gross TG, Beebe TM, Trofe J, Alloway RR, Woodle ES, Buell JF. 2004. Characteristics and survival patterns of solid organ transplant patients developing de novo colon and rectal cancer.  Dis Colon Rectum. Vol. 47, no. January: 1898-1903.
  • Aull MJ, Buell JF, Trofe J, First MR, Alloway RR, Hanaway MJ, Wagoner L, Gross TG, Beebe T, Woodle ES. 2004. Experience with 274 cardiac transplant recipients with post-transplant lymphoproliferative disorder: a report from the Israel Penn International Transplant Tumor Registry.  Transplantation. Vol. 78, no. January: 1676-1682.
  • Greiner TC, Gross TG. 2004. Atypical Immune Lymphoproliferations. In Hematology: Basic Principles and Practice. 4th ed. Edited by Hoffman, et al. Philadelphia, PA: Churchill Livingstone.
  • Filipovich AH, Gross TG. 2004. Immunodeficiency and cancer. In Clinical Oncology. 3rd ed. Edited by Martin D. Abeloff, et al. Portland, OR: Book News, Inc.
  • Gross TG. 2004. Infectious Mononucleosis and other EBV-related disorders. In Wintrobe’s Clinical Hematology. 11th ed. Edited by JP Greer, J Foerster, JN Lukens, et al. Philadelphia, PA: Lippincott Williams and Wilkins.
  • Trofe J, Beebe TM, Buell JF, Hanaway MJ, First MR, Alloway RR, Gross TG, Woodle ES. 2004. Posttransplant malignancy.  Prog Transpl. Vol. 14, no. January: 193-200.
  • Guthrey SL, Heubi JH, Bucuvalas JC, Gross TG, Ryckman FC, Alonso MH, Balistreri WF, Hornung RW. 2003. Determination of risk factors for Epstein-Barr virus-associated post-transplant lymphoproliferative disorder in pediatric liver transplant recipients using objective case ascertainment.  Transplantation. Vol. 75, no. January: 987-993.
  • Buell JF, Trofe J, Sethuraman G, Hanaway MJ, Beebe TM, Gross TG, Alloway R, First MR, Woodle ES. 2003. Donors with central nervous system malignancies: are they truly safe?.  Transplantation. Vol. 76, no. January: 340-343.
  • Yeager ND, Dolan ME, Gastier JM, GrossTG, Delaney S, Frick J, Ruymann FB, Ewesuedo R. 2003. O6-Methylguanine-DNA Methyltransferase Activity and Promoter Methylation Status in Pediatric Rhabdomyosarcoma.  J Pediatr Hematol Oncol. Vol. 25, no. January: 941-947.
  • Boyer MW, Gross TG, Loechelt BJ, Leemhuis T, Filipovich AH, Harris RE. 2003. Low risk of GVHD with transplantation of CD34 selected peripheral blood stem cells from alternative donors for Fanconi anemia.  J Pediatr Hematol Oncol. Vol. 25, no. January: 890-895.
  • Gross TG, Loechelt BJ. 2002. Post-transplant Epstein-Barr virus (EBV) associated disease. In Current Clinical Oncology - Allogeneic Stem Cell Transplantation. Edited by H Lazarus, M Laughlin. Totowa, NJ: Humana Press Inc.
  • Sumegi J, Seemayer TA, Huang D, Davis JR, Morra M, Gross TG, Yin L, Romeo G, Klein E, Cox T, Lanyi A. 2002. A spectrum of mutations in SH2D1a that causes X-linked lymphoproliferative disease and other Epstein-Barr virus-associated illnesses.  Leuk Lymphoma. Vol. 43, no. January: 1189-1201.
  • Buell JF, Husted T, Hanaway MJ, Trofe J, Gross T, Beebe T, First MR, Woodle ES. 2002. Gastric cancer in transplant recipients: Detection of malignancy by aggressive endoscopy.  Transplant Proc. Vol. 34, no. January: 1784-1785.
  • Mack DR, Beedle S, Warren J, Davis J, Gross T. 2002. T-cell activation in newly diagnosed, non-treated children with inflammatory bowel disease.  Pediatr Res. Vol. 51, no. January: 328-332.
  • Buell JF, Hanaway MJ, Trofe J, Gross TG, Beebe TM, Alloway RR, First MR, Woodle ES. 2002. Immunosuppression and Merkel cell cancer.  Transplant Proc. Vol. 34, no. January: 1780-1781.
  • Buell JF, Husted T, Hanaway MJ, Peddi VR, Trofe J, Gross TG, Beebe TM, First MR, Woodle ES. 2002. Incidental diagnosis of gastric cancer in transplant recipients improves patient survival.  Surgery. Vol. 132, no. January: 754-758.
  • Buell JF, Hanaway MJ, Trofe J, Gross TG, Beebe TM, Alloway RR, First MR, Woodle ES. 2002. De novo breast cancer in renal transplant recipients.  Transplant Proc. Vol. 34, no. January: 1778-1779.
  • Husted TL, Buell JF, Hanaway MJ, Trofe J, Gross T, First MR, Woodle ES. 2002. De Novo sarcomas in solid organ transplant recipients.  Transplant Proc. Vol. 34, no. January: 1786-1787.
  • Nichols KE, Gross TG. 2002. X-linked lymphoproliferative Disease. In Immunology and Allergy Clinics of North America – Immunodeficiency Disorders. Philadelphia, PA: WB Saunders Co.
  • Gross TG. 2002. Low-dose chemotherapy for treatment of children with PT-LPD. In Recent Results Cancer Res, Immunosurveillance, immunodeficiencies and lymphoproliferations. Edited by SH Oertel, HB Riess. New York, NY: Springer-Verlag Berlin-Heidelberg.
  • Woodle ES, Hanaway M, Buell J, Gross T, First MR, Trofe J, Beebe T. 2001. Kaposi sarcoma: an analysis of the US and international experiences from the Israel Penn International Transplant Tumor Registry.  Transplant Proc. Vol. 33, no. January: 3660-3661.
  • Okano M, Gross TG. 2001. From Burkitt's lymphoma to chronic active Epstein-Barr virus (EBV) infection: an expanding spectrum of EBV-associated diseases.  Pediatr Hematol Oncol. Vol. 18, no. January: 427-442.
  • Gross TG, Egeler RM, Smith FO. 2001. Hematopoietic stem cell transplantation. In Hematology/Oncology Clinics of North America – Pediatric Oncology. Edited by MJ Coppes. Philadelphia, PA: WB Saunders Co.
  • Ziegner UHM, Ochs HD, Schanen C, Fieg SA, Seyama K, Futatani T, Gross T, Wakim M, Roberts RL, Rawlings DJ, Dovat S, Fraser JK, Stiehm ER. 2001. Unrelated umbilical cord stem cell transplantation in X-linked immunodeficiencies.  J Pediatr. Vol. 138, no. January: 570-573.
  • Okano M, Gross TG. 2000. A review of Epstein-Barr virus infection in patients with immunodeficiency disorders.  Am J Med Sci. Vol. 319, no. January: 392-396.
  • Greiner TC, Abou-Elella AA, Smir BN, Orazi A, Hinrichs S, Anderson J, Gross T, Bierman P, Hauke R. 2000. EBNA-1 substrain and p53 mutation analysis in Epstein-Barr virus positive posttransplant lymphoproliferative disorders.  Leuk Lymphoma. Vol. 38, no. January: 563-576.
  • Sumegi J, Huang D, Lanyi A, Davis JR, Maeda A, Serri M, Wakiguchi H, Seemayer TA, Klein G, Purtilo DT, Gross TG. 2000. Correlation of mutations of the SH2D1A gene and Epstein-Barr virus (EBV) infection with clinical phenotype and outcome in X-linked lymphoproliferative disease (XLP).  Blood. Vol. 96, no. January: 3118-3125.
  • Greiner TC, Armitage JO, Gross TG. 2000. Atypical lymphoid diseases. In Hematology. Washington, DC: American Society of Hematology Education Program.
  • Greiner TC, Gross TG. 2000. Atypical Immune Lymphoproliferations. In Hematology: Basic Principles and Practice. 3rd ed. Edited by Hoffman, et al. Philadelphia, PA: Churchill Livingstone.
  • Seemayer TA, Greiner TC, Gross TG, Lanyi A, Sumegi J. 2000. X-linked lymphoproliferative disease. In Infectious Causes of Cancer: Targets for Intervention. Totowa, NJ: Humana Press, Inc.
  • Gross TG, Steinbuch M, DeFor T, Shapiro RS, McGlave P, Ramsay NKC, Wagner JE, Filipovich AH. 1999. B cell lymphoproliferative disorder following hematopoietic stem cell transplantation: Risk factors, treatment and outcome.  Bone Marrow Transpl. Vol. 23, no. January: 251-258.
  • Heuermann KG, Romero JR, Abromowitch MA, Gordon BG, Gross TG. 1999. Fatal coagulase-negative staphylococci infection following bone marrow transplantation in a patient with persistent adverse reactions to vancomycin.  J Pediatr Hematol Oncol. Vol. 21, no. January: 80-81.
  • Sumegi J, Gross TG, Seemayer TA. 1999. The molecular genetics of X-linked lymphoproliferative (Duncan’s) disease.  Cancer J Sci Am. Vol. 5, no. January: 57-62.
  • Balfour IC, Wall D, Luisiri A, Gross TG. 1999. Cyclophosphamide/prednisone for combination immunosuppression and therapy of post-transplant lymphoproliferative disease.  . J Heart Lung Transpl. Vol. 18, no. January: 492-495.
  • Davis KR, Hinrichs SH, Fidler JL, Henry TJ, Davis JR, Baker KS, Gordon BG, Gross TG. 1999. Post-transplant Epstein-Barr virus associated meningoencephalitis and lymphoid interstitial pneumonitis.  Bone Marrow Transpl. Vol. 24, no. January: 443-444.
  • Baker KS, Gordon BG, Gross TG, Abromowitch MA, Ruby E, Vose JM, Armitage JO, Coccia PF, Bierman PJ. 1999. Autologous hematopoietic stem cell trans¬plantation for relapsed or refractory Hodgkin's disease in children and adolescents.  J Clin Oncol. Vol. 17, no. January: 825-831.
  • Gross TG, Hinrichs SH, Davis JR, Fuller S, Mitchell D, Bishop MR, Wagner JE. 1998. Effect of counterflow elutriation (CE) on Epstein-Barr virus (EBV) infected cells in donor bone marrow.  Exp Hematol. Vol. 26, no. January: 395-399.
  • Joshi SS, Babushkina-Patz NN, Verbik DJ, Gross TG, Tarantolo SR, Kuszynski CA, Pirruccello SJ, Bishop MR, Kessinger A. 1998. Antitumor activity of human umbilical coed blood cells: a comparative analysis with peripheral blood and bone marrow cells.  Int J Oncol. Vol. 13, no. January: 791-799.
  • Pavletic ZS, Joshi SS, Pirruccello SJ, Tarantolo SJ, Reed EC, Bierman PJ, Vose JM, Gross TG, Kollath J, Nasrati K, Armitage JO, Kessinger A, Bishop MR. 1998. Immunologic reconstitution after allo¬geneic blood stem cell transplantation for hematologic malignancies: Early lymphocyte recovery cor¬relates with better survival.  Bone Marrow Transpl. Vol. 21, no. January: 33-41.
  • Gross TG, Hinrichs SH, Winner J, Greiner TC, Kaufman S, Sammut PH, Langnas AN. 1998. Treatment of post-transplant lymphoproliferative disease (PTLD) following solid organ transplantation with low dose chemotherapy.  Ann Oncol. Vol. 9, no. January: 339-340.
  • KS, DeLaat CA, Shapiro RS, Gross TG, Steinbuch M, Filipovich AH. 1997. Successful correction of hemophagocytic lymphohistiocytosis with related and unrelated bone marrow transplantation.  Blood. Vol. 89, no. January: 3857-3863.
  • Seemayer TA, Harper JL, Sheckell D, Gross TG. 1997. Cytodifferentiation of Wilms’ tumor pulmonary metastasis: theoretic and clinical implications.  Cancer. Vol. 79, no. January: 1629-1634.
  • Lanyi A, Li B, Li, S, Talmadge CB, Brichacek B, Davis JR, Trask B, van den Engh G, Stanbridge EJ, Nelson DL, Chinault C, Heslop H, Gross TG, Seemayer TA, Klein G, Purtilo DT, Sumegi J. 1997. A yeast artificial chromosome (YAC) contig encompassing the critical region of the X-linked lympho¬proliferative disease (XLP) locus.  Genomics. Vol. 39, no. January: 55-65.
  • Dhawan A, Seemayer TA, Pinsinski C, Gross TG, Shaw BW, Mack DR. 1997. Posttransplant eosino¬philic gastroenteritis in children.  Liver Transpl and Surg. Vol. 3, no. January: 591-593.
  • Pavletic ZS, Bishop MR, Tarantolo SR, Martin-Algarra S, Bierman PJ, Vose JM, Reed EC, Gross TG, Kollath J, Nasrati K, Jackson JD, Armitage JO, Kessinger A. 1997. Hematopoietic recovery after stem cell transplantation compared to bone marrow transplantation in patients with hematologic malignancies.  J Clin Oncol. Vol. 15, no. January: 1608-1616.
  • Pelkonen T, Lanning M, Kahkonen M, Gross TG. 1996. X-linked lymphoproliferative disease.  Duodecim. Vol. 112, no. January: 407-411.
  • Filipovich AH, Jyonouchi H, Gross TG, Shapiro RS. 1996. Hematologic and oncologic complications of primary and secondary immunodeficiencies, including EBV related disorders. In Immunologic Dis¬orders of Infants and Children. 4th ed. Edited by ER Stiehm. Philadelphia, PA: WB Saunders Co..
  • Mills KC, Gross TG, Varney ML, Heimann DG, Reed EC, Kessinger A, Talmadge JE. 1996. Immunologic phenotype and function in human bone marrow, blood stem cells and umbilical cord blood.  Bone Marrow Transpl. Vol. 18, no. January: 53-61.
  • McConnell JR, Ong CS, McAllister J, Gross TG. 1996. In vivo detection of brain propylene glycol by proton magnetic resonance spectroscopy.  Neurosurgery. Vol. 38, no. January: 232-233.
  • Gross TG, Hilden JM, Manivel JC, Ramsay NKC, MacMahon EME. 1996. Concurrent Epstein-Barr associated non-Hodgkin lymphoma with relapsed Hodgkin disease.  J Pediatr Hematol Oncol. Vol. 18, no. January: 182-186.
  • Okano M, Gross TG. 1996. Epstein-Barr virus-associated hemophagocytic syndrome and fatal infectious mononucleosis.  Am J Hematol. Vol. 53, no. January: 111-115.
  • Gross TG, Filipovich AH, Conley ME, Pracher E, Schmiegelow K, Verdirame JD, Vowels MR, Williams LL, Seemayer TA. 1996. Cure of X-linked lymphoproliferative disease (XLP) with allogeneic bone marrow transplantation (BMT): Report from the XLP Registry.  Bone Marrow Transpl. Vol. 17, no. January: 741-744.
  • Smir BN, Hauke RJ, Bierman PJ, Gross TG, d’Amore F, Anderson JR, Greiner TC. 1996. Molecular epidemiology of deletions and mutations of the LMP1 oncogene of Epstein-Barr virus in posttransplant lymphoproliferative disorders.  Lab Invest. Vol. 75, no. January: 575-588.
  • Seemayer TA, Gross TG, Egeler RM, Pirruccello SJ, Davis JR, Kelly CM, Okano M, Lanyi A, Sumegi J. 1995. X-linked lymphoproliferative disease: Twenty-five years after the discovery.  Pediatr Res. Vol. 38, no. January: 471-478.
  • Seemayer TA, Gross TG, Hinrichs S, Egeler RM. 1994. Massive diffuse histiocytic myocardial infiltration¬ in Epstein-Barr virus-induced fatal infectious mononucleosis.  Cell Visions. Vol. 1, no. January: 260-264.
  • Gross TG, Hoge FJ, Jackson JD, Sammut PH, Warkentin PI. 1994. Fatal eosinophilia following autologous bone marrow transplantation.  Bone Marrow Transp. Vol. 14, no. January: 333-337.
  • Bendel AE, Gross TG, Endelman C, Woods W, Balfour H. 1993. Failed treatment of disseminated varicella-zoster following bone marrow transplantation with acyclovir and foscarnet.  Lancet. Vol. 341, no. January: e1342.
  • Seemayer TA, Grierson H, Pirruccello SJ, Gross TG, Weisenburger DD, Davis J, Spiegel K, Brichacek B , Sumegi J. 1993. X-linked lymphoproliferative disease.  Am J Dis Child. Vol. 147, no. January: 1242-45.
  • Okano M, Thiele GM, Gross TG, Davis JR, Purtilo DT. 1990. Different cell susceptibility to Epstein-Barr virus infection in a patient with X-linked lymphoproliferative disease.  J Med Virol. Vol. 32, no. January: 47-52.
  • Okano M, Thiele GM, Gross TG, Davis JR, Purtilo DT. 1989. Different cell susceptibility to Epstein-Barr virus infection in a patient with X-linked lymphoproliferative syndrome. In Epstein-Barr Virus and Human Disease. Edited by DV Abashi, et al. Clifton, NJ: Humana Press.
  • Gross TG, Sakai K, Volsky DJ. 1986. Transfer of the Epstein-Barr virus (EBV) DNA fragment coding for EBNA-1, the putative transforming antigen of EBV, into normal human lymphocytes: Gene expres¬sion without transformation.  Biochem and Biophys Res Comm. Vol. 134, no. January: 1260-68.
  • Volsky DJ, Gross TG, Bartzatt R, Kuszynski C, Volsky B, Sinangil F. 1985. Transformation of human lymphocytes after transfer of purified EBV DNA in the presence of UV-inactivated virions or P3HR-1 EBV. In Epstein-Barr Virus and Associated Diseases. Edited by PH Levine, et al. Clifton, NJ: Humana Press.
  • Volsky DJ, Gross TG, Volsky B, Bartzatt R, Kuszynski C, Sinangil F. 1984. Mapping of genes involved in Epstein-Barr virus (EBV)-induced lymphocyte transformation. In Genes and Cancer.. UCLA Sym¬posia on Molecular and Cellular Biology ed. Edited by JM Bishop, M Greaves and JD Rowley. New York, NY: Alan R. Liess, Inc.
  • Volsky DJ, Bartzatt R, Kuszynski C, Sinangil F, Gross TG. 1984. Transformation of human cord blood lymphocytes by coinfection with UV-inactivated Epstein-Barr virus (EBV) and purified EBV DNA. In Herpesvirus. . UCLA Symposia on Molecular and Cellular Biology ed. Edited by F Rapp. New York, NY: Alan R. Liess, Inc.
  • Volsky DJ, Gross T, Sinangil F, Volsky B, Bartzatt R, Dambaugh T, Kieff E. 1984. Expression of Epstein-Barr virus (EBV) DNA and cloned DNA fragments in human lympocytes following Sendai virus envelope-mediated gene transfer.  Proc Natl Acad Sci USA. Vol. 81, no. January: 5926-30.
  • Gross TG, Volsky DJ. 1984. Infection of mouse lymphocytes by Epstein-Barr virus: II. Stimulation of cellular DNA synthesis by EBV in the absence of EBNA in the absence of EBNA induction and cell transformation.  Virology. Vol. 133, no. January: 211-215.
  • Volsky DJ, Gross TG, Sinangil F, Shapiro I, King W, Kieff E. 1983. Functional mapping of the Epstein-Barr virus (EBV) genome using Sendai virus-envelope-mediated gene transfer. In Normal and Neoplastic Hematopoiesis. UCLA Symposia on Molecular and Cellular Biology ed. Edited by DW Golde and PA Parks. New York, NY: Alan R. Liess, Inc..

Awards, Honors and Organizations

  • Listed, Best Doctors in America
Nationwide Children's Hospital
700 Children's Drive Columbus, Ohio 43205 614.722.2000