Robert G. Castile, MD, MS :: Nationwide Children’s Hospital, Columbus, Ohio

Robert G. Castile, MD, MS

Robert G. Castile, MD, MS Best Doctors 2011-2012

Center for Perinatal Research
Principal Investigator

Hospital-Based Research Faculty
Principal Investigator

Jeune's Syndrome
Physician Team

Principal Investigator

Pulmonary Medicine
Physician Team

Contact Information

Perinatal Research Building III 5213
700 Children's Dr
Columbus, OH 43205 [ map ]
PH: (614) 355-6670
FX: (614) 355-5899
Email Me
The Research Institute at Nationwide Children's Hospital
700 Childrens Drive
Columbus, OH 43205 [ map ]
PH: (614) 722-2700

Location Information for Patients

Main Campus


Robert G. Castile, MD, MS, is a member of the Center for Perinatal Research at The Research Institute at Nationwide Children’s Hospital and the Section of Pulmonary Medicine at Nationwide Children’s Hospital. He is also professor of Pediatrics at The Ohio State University College of Medicine. His undergraduate and medical training was done at the University of Maryland. His residency training in pediatrics was done at the Mayo Clinic. His fellowship training was done at Children’s Hospital in Boston, where he practiced pediatric pulmonology for 14 years prior to moving to Columbus, Ohio. He also holds a master’s degree in pediatrics from the University of Minnesota. He has been engaged in research and clinical practice in the area of lung disorders of infants and children for more than 40 years. His research interests include infant pulmonary function testing, CT lung imaging, lung growth, bronchopulmonary dysplasia, cystic fibrosis, asthma, Jeune’s syndrome and interstitial lung diseases. He has been a frequent speaker at national and international medical meetings and has more than 85 peer-reviewed publications.

View CV »


  • Male

Languages Spoken:

  • English

Research Interests

Research Center:

Research Funding*:

  • Two-Year Study to Assess the Natural hx of Progressive CF Lung Disease Utilizing CT Imaging, PFTs and Clinical Scores, CR Therapeutics Development Network/Anonymous
  • Changes in Lung Structure and Function in Children with Cystic Fibrosis, Cystic Fibrosis Foundation
  • HRCT & Growth in Preschoolers Receiving Behavioral Tx, Children’s Hospital Medical Center Cincinnati/Cystic Fibrosis Foundation
  • Cystic Fibrosis Treatment Study, Anonymous

Education and Training

Undergraduate School

  • University of Maryland
    Date Completed: 06/30/1969

Medical School

  • University of Maryland
    Date Completed: 06/30/1973


  • Mayo Clinic (Rochester)
    Date Completed: 06/30/1974


  • Mayo Clinic (Rochester)
    Date Completed: 06/30/1976


  • Mayo Clinic (Rochester)
    Date Completed: 06/30/1978

Graduate School

  • University of Minnesota
    Date Completed: 06/30/1979


  • Boston Children's Hospital
    Date Completed: 06/30/1980


  • The Children's Hospital and Harvard Medical School
    Date Completed: 06/30/1981


  • Pediatrics


  • Pulmonary Medicine


  • Pediatric Pulmonary Medicine
  • Pediatrics

Date of Appointment at Nationwide Children’s Hospital:

  • 05/11/1993

Professional Experience


  • Professor of Pediatrics, Ohio State University of Medicine, Columbus, OH


  • Associate Professor of Pediatrics, Ohio State University of Medicine, Columbus, OH


  • Associate Professor of Pediatrics, Tufts University School of Medicine, Tufts New England Medical Center, Boston, MA


  • Lecturer in Medicine, Harvard Medical School, Boston, MA


  • Assistant Professor of Pediatrics, Tufts University School of Medicine, Tufts New England Medical Center, Boston, MA


  • Assistant Professor of Pediatrics, Harvard medical School, Boston, MA


  • Instructor in Pediatrics, Harvard Medical School, Boston, MA


  • Research Associate, Department of Physiology, Harvard School of Public Health, Boston, MA


  • Kerby GS, Rosenfeld M, Ren CL, Mayer OH, Brumback LC, Castile R, Hart M, Hiatt PW, Kloster M, Johnson R, Jones P, Davis SD. 2011. Lung function distinquishes preschool children with cystic fibrosis from healthy controls in a multicenter setting.  Am J Respir Crit Care Med.
  • Castile RG, Davis SD. 2011. Pulmonary Function Testing in Children. In Disorders of the Respiratory Tract in Children. 8th ed. Edited by Chernick V, Boat T, Wilmott R, Bush A, Ratjen F, Deterding R. Philadelphia, PA: W.B. Saunders, Inc..
  • Ren CL, Rosenfeld M, Mayer OH, Davis SD, Kloster M, Castile R, Hiatt PW, Hart M, Johnson R, Jones P, Brumback LC, Kerby GS. 2011. Analysis of the association between lung function and clinical features in preschool cystic fibrosis.  Am Rev Respir Crit Care Med.
  • Sontag MK, Quittner AL, Modi AC, Koenig JM, Giles D, Oermann CM, Konstan MW, Castile R, Accurso FJ. 2010. Lessons learned from a randomized trial of airway secretion clearance techniques in cystic fibrosis.  Pediatr Pulmonol. Vol. 45, no. January: 291-300.
  • Davis SD, Rosenfeld M, Kerby G, Brumback L, Kloster M, Acton J, Colin A, Conrad C, Hart M, Hiatt P, Mogayzel P, Johnson R, Wilcox S, Castile R. 2010. Multicenter longitudinal evaluation of infant lung function tests as clinical trial endpoints.  Am J Respir Crit Care Med. Vol. 182, no. January: 1387-1397.
  • Brody A, Castile R, Deterding R, Fan L, Hagwood J, Hilman B, Kurland G, Langston C, Nogee L, Redding G, Young L. 2010. Interstitial lung disease in infants and children: Clinical description, pathologic classification, evaluation, and management: An ATS consensus statement.  Am J Repir Crit Care Med.
  • Colin AA, McEvoy C, Castile RG. 2010. Respiratory morbidity and lung function in preterm infants 32-36 weeks gestational age.  Pediatrics. Vol. 126, no. January: 115-128.
  • Mueller KS, Long FL, Flucke RL, Castile RG. 2010. Volume monitored chest CT: A simplified method for obtaining motion free images near full inspiratory and end expiratory lung volumes.  Pediatr Radiol. Vol. 40, no. January: 1663-1669.
  • Long F, Adler B, Castile R. 2010. Comparison of quantitative thin-section CT and pulmonary function tests for the assessment of air trapping in infants and young children with cystic fibrosis.  Pediatr Radiol.
  • Castile, RG. 2010. High resolution CT scans of the chest should be a routine part of CF lung disease assessment: Pro.  Pediatr Pulmonol. Vol. Suppl 33, no. January: 130-131.
  • Mumcuoglu EU, Long F, Castile RG, Gurcan MN. 2010. Image analysis for cystic fibrosis: Automated airway wall and vessel measurements from CT images of the lungs.  IEEE Transactions on Medical Imaging.
  • Castile RG, Nelin LD. 2009. Lung function, structure and the physiologic basis for mechanical ventilation of infants with established BPD. In Bronchopulmonary Dysplasia. Edited by Abman SH. New York, NY: Marcel Dekker, Inc..
  • Mumcuoglu EU, Prescott J, Baker BN, Clifford B, Long F, Castile R, Gurcan MN. 2009. Image analysis for cystic fibrosis: Automatic lung airway wall and vessel measurement on CT images.  Conf Proc IEEE Eng Med Biol Soc. Vol. 1, no. January: 3545-3548.
  • Jadcherla SR, Gupta A, Fernandez S, Nelin LD, Castile R, Gest AL, Welty S. 2008. Spatiotemporal characteristics of acid refluxate and relationship to symptoms in premature and term infants with chronic lung disease.  Am J Gastroenterol.. Vol. 103, no. 3. (March): 720-728.
  • Davis JT, Phillips ABM, Long FR, Castile RG. 2007. Staged Surgical Approach to Thoracic Expansion in Jeune Syndrome and other Asphyxiating Thoracic Dystrophies. In Re-Operative Pediatric Surgery. Edited by Teich S, Caniano DA. Totowa, NJ: Humana Press.
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700 Children's Drive Columbus, Ohio 43205 614.722.2000