Robert G. Castile, MD, MS

Robert G. Castile, MD, MS, is a member of the Center for Perinatal Research at The Research Institute at Nationwide Children’s Hospital and the Section of Pulmonary Medicine at Nationwide Children’s Hospital and a Professor of Pediatrics at The Ohio State University College of Medicine. His undergraduate and medical training was done at the University of Maryland. His residency training in pediatrics was done at the Mayo Clinic in Rochester, Minnesota. His fellowship training was done at Children’s Hospital in Boston, where he practiced pediatric pulmonology for 14 years prior to moving to Columbus, Ohio. He also holds a master’s degree in pediatrics from the University of Minnesota. He has been engaged in research and clinical practice in the area of lung disorders of infants and children for more than 30 years. His research interests include infant pulmonary function testing, CT lung imaging, lung growth, bronchopulmonary dysplasia, cystic fibrosis, asthma, Jeune’s syndrome and interstitial lung diseases. He is a frequent speaker at national and international medical meetings and has more than 70 peer-reviewed publications.

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Gender:

• Male

Languages Spoken:

• English

Research Center:

• Center for Perinatal Research

Research Funding*:

• Two-Year Study to Assess the Natural hx of Progressive CF Lung Disease Utilizing CT Imaging, PFTs and Clinical Scores, CR Therapeutics Development Network/Anonymous
• Changes in Lung Structure and Function in Children with Cystic Fibrosis, Cystic Fibrosis Foundation
• HRCT & Growth in Preschoolers Receiving Behavioral Tx, Children’s Hospital Medical Center Cincinnati/Cystic Fibrosis Foundation
• Cystic Fibrosis Treatment Study, Anonymous

Undergraduate

• University of Maryland
  Date Completed: 06/30/1969

Medical School

• University of Maryland
  Date Completed: 06/30/1973

Internship

• Mayo Clinic (Rochester)
  Date Completed: 06/30/1974

Residency

• Mayo Clinic (Rochester)
  Date Completed: 06/30/1976

Fellowship

• Mayo Clinic (Rochester)
  Date Completed: 06/30/1978

Graduate School

• University of Minnesota
  Date Completed: 06/30/1979

Fellowship

• Children's Hospital Boston
  Date Completed: 06/30/1980

Fellowship

• The Children's Hospital and Harvard Medical School
  Date Completed: 06/30/1981

Department:

• Pediatrics

Section:

• Pulmonary Medicine

Speciality:

• Pediatric Pulmonary Medicine, Certified
  
• Pediatrics, Certified
  

Date of Appointment at Children's Hospital:

• 05/11/1993

2001–present

• Professor of Pediatrics, Ohio State University of Medicine, Columbus, OH

1992–2001

• Associate Professor of Pediatrics, Ohio State University of Medicine, Columbus, OH

1989–1992

• Associate Professor of Pediatrics, Tufts University School of Medicine, Tufts New England Medical Center, Boston, MA

1987–1992

• Lecturer in Medicine, Harvard Medical School, Boston, MA

1987–1989

• Assistant Professor of Pediatrics, Tufts University School of Medicine, Tufts New England Medical Center, Boston, MA

1983–1986

• Assistant Professor of Pediatrics, Harvard medical School, Boston, MA

1980–1983

• Instructor in Pediatrics, Harvard Medical School, Boston, MA

1980–1981

• Research Associate, Department of Physiology, Harvard School of Public Health, Boston, MA

• Castile RG, Davis SD. 2011. Pulmonary Function Testing in Children. In Disorders of the Respiratory Tract in Children. 8th ed. Edited by Chernick V, Boat T, Wilmott R, Bush A, Ratjen F, Deterding R. Philadelphia, PA, USA: W.B. Saunders, Inc. (Formally Accepted)
• Ren CL, Rosenfeld M, Mayer OH, Davis SD, Kloster M, Castile R, Hiatt PW, Hart M, Johnson R, Jones P, Brumback LC, Kerby GS. 2011. Analysis of the association between lung function and clinical features in preschool cystic fibrosis.  Am Rev Respir Crit Care Med. (Unspecified)
• Long F, Yan Y, Castile R. 2011. Volumetric inspiratory/expiratory chest computed tomography findings in bronchopulmonary dysplasia [Abstract]. Pediatr Radiol [Peer Reviewed] (Formally Accepted)
• Kerby GS, Rosenfeld M, Ren CL, Mayer OH, Brumback LC, Castile R, Hart M, Hiatt PW, Kloster M, Johnson R, Jones P, Davis SD. 2011. Lung function distinquishes preschool children with cystic fibrosis from healthy controls in a multicenter setting.  Am J Respir Crit Care Med. (Unspecified)
• Brumback LC, Davis SD, Kerby GS, Kloster M, Johnson R, Castile R, Hiatt PW, Rosenfeld M. 2010. Lung function from infancy through preschool in a cohort of children with CF [Abstract]. Pediatr Pulmonol. Vol. Suppl 33: 365-365. [Peer Reviewed] (Published)
• Brody A, Castile R, Deterding R, Fan L, Hagwood J, Hilman B, Kurland G, Langston C, Nogee L, Redding G, Young L. 2010. Interstitial lung disease in infants and children: Clinical description, pathologic classification, evaluation, and management: An ATS consensus statement.  Am J Repir Crit Care Med. (Formally Accepted)
• Long F, Adler B, Castile R. 2010. Comparison of quantitative thin-section CT and pulmonary function tests for the assessment of air trapping in infants and young children with cystic fibrosis.  Pediatr Radiol. (Unspecified)
• Colin AA, McEvoy C, Castile RG. 2010. Respiratory morbidity and lung function in preterm infants 32-36 weeks gestational age.  Pediatrics. Vol. 126. : 115-128.
• Castile, RG. 2010. High resolution CT scans of the chest should be a routine part of CF lung disease assessment: Pro.  Pediatr Pulmonol. Vol. Suppl 33. : 130-131.
• Sontag MK, Quittner AL, Modi AC, Koenig JM, Giles D, Oermann CM, Konstan MW, Castile R, Accurso FJ. 2010. Lessons learned from a randomized trial of airway secretion clearance techniques in cystic fibrosis.  Pediatr Pulmonol. Vol. 45. : 291-300.
• Mumcuoglu EU, Long F, Castile RG, Gurcan MN. 2010. Image analysis for cystic fibrosis: Automated airway wall and vessel measurements from CT images of the lungs.  IEEE Transactions on Medical Imaging. (Unspecified)
• Mueller KS, Long FL, Flucke RL, Castile RG. 2010. Volume monitored chest CT:A simplified method for obtaining motion free images near full inspiratory and end expiratory lung volumes [Abstract]. Pediatr Radiol. Vol. 40: 574-574. [Peer Reviewed] (Formally Accepted)
• Davis SD, Rosenfeld M, Kerby G, Brumback L, Kloster M, Acton J, Colin A, Conrad C, Hart M, Hiatt P, Mogayzel P, Johnson R, Wilcox S, Castile R. 2010. Multicenter longitudinal evaluation of infant lung function tests as clinical trial endpoints.  Am J Respir Crit Care Med. Vol. 182. : 1387-1397.
• Ren CL, Rosenfeld M, Davis SD, Mayer OH, Kloster M, Castile R, Hiatt PW, Hart M, Johnson R, Brumback LC, Kerby GS. 2010. Analysis of the association between clinical features and lung function in preschool CF [Abstract]. Pediatr Pulmonol. Vol. Suppl 33: 366-366. [Peer Reviewed] (Published)
• Mueller KS, Long FL, Flucke RL, Castile RG. 2010. Volume monitored chest CT: A simplified method for obtaining motion free images near full inspiratory and end expiratory lung volumes.  Pediatr Radiol. Vol. 40. : 1663-1669.
• Castile R, Mueller G, Long F, Flucke R, Baker B, Clifford B. 2009. Effects of nebulized recombinant human deoxyribonuclease (dornase alpha) in infants with cystic fibrosis evaluated using infant pulmonary function testing and high resolution computerized tomographic imaging of the chest [Abstract]. Pediatr Pulmonol. Vol. 32: 357. [Peer Reviewed] (Published)
• Castile RG, Nelin LD. 2009. Lung function, structure and the physiologic basis for mechanical ventilation of infants with established BPD. In Bronchopulmonary Dysplasia. Edited by Abman SH. New York, NY: Marcel Dekker, Inc.
• Kerby GS, Rosenfeld M, Ren C, Mayer OH, Castile R, Hart M, Hiatt P, Kloster M, Brumback L, Johnson R, Davis SD. 2009. Spirometry distinguishes preschool children with CF from healthy controls in a multicenter setting [Abstract]. Pediatr Pulmonol Suppl. Vol. 32: 293. [Peer Reviewed] (Published)
• Mumcuoglu EU, Prescott J, Baker BN, Clifford B, Long F, Castile R, Gurcan MN. 2009. Image analysis for cystic fibrosis: Automatic lung airway wall and vessel measurement on CT images.  Conf Proc IEEE Eng Med Biol Soc. Vol. 1: 3545-3548.
• Jadcherla SR, Gupta A, Wang M, Long F, Castile R. 2009. Characterization of esophageal dysmotility in relation to altered pulmonary structure and function in chronic lung disease of infancy [Abstract]. Pediatric Academic Societies, Annual Meeting: A-754140. [Peer Reviewed] (Published)
• Mumcuoglu EU, Prescott J, Baker BN, Clifford B, Long F, Castile R, Gurcan MN. 2009. Image analysis for cystic fibrosis: Automatic lung airway wall and vessel measurement on CT images [Abstract]. Engineering in Medicine and Biology [Peer Reviewed] (Published)
• Jadcherla SR, Gupta A, Fernandez S, Nelin LD, Castile R, Gest AL, Welty S. 2008. Spatiotemporal characteristics of acid refluxate and relationship to symptoms in premature and term infants with chronic lung disease. Am J Gastroenterol.. Vol. 103, no. 3. (March): 720-728. (IF: 6.101)
• Davis JT, Phillips ABM, Long FR, Castile RG. 2007. Staged Surgical Approach to Thoracic Expansion in Jeune Syndrome and other Asphyxiating Thoracic Dystrophies. In Re-Operative Pediatric Surgery. Edited by Teich S, Caniano DA. Totowa, NJ: Humana Press.