Pam Lucchesi, Ph.D.

Gender:

• Female

Languages Spoken:

• English

Research Center:

• Center for Cardiovascular and Pulmonary Research

Areas of Interest:

• The Lucchesi Lab focuses on the complex interactions between hemodynamic and transmural forces, neurohormones and oxidative lead to activation of signaling cascades that regulate cardiovascular remodeling and function during disease progression. A conbination of animal models, in vivo measurements of blood flow, cardiac function (echocardiography and pressure-volume conductance catheters), in situ measurements of vessel structure, single cell-functional analysis and biochemical, molecular and proteomic approaches are used to characterize disease progression. Ongoing projects include the role the renin-angiotensin system and advanced glycation end products in Type 2 diabetes-associated coronary artery remodeling; molecular mechanisms that reverse heart failure progression in response to hemodynamic overload; cardiac chamber- and vascular bed-specific remodeling; and ductus arteriosus pathophysiology. Lab Web Site: http://www.nationwidechildrens.org/lucchesi-lab

Undergraduate

• Assumption College
  Date Completed: 06/30/1983

Post Doctoral

• University of Massachusetts Medical School
  Date Completed: 06/30/1989

Fellowship

• Harvard Medical School, Boston, MA. Neurosurgery Unit, Massachusetts General Hospital
  Date Completed: 06/30/1991

Fellowship

• Department of Medicine, Division of Cardiology Boston University School of Medicine
  Date Completed: 06/30/1992

Fellowship

• Department of Medicine, Division of Cardiology Emory University School of Medicine
  Date Completed: 06/30/1993

2008–present

• Professor, Department of Pediatrics Ohio State University  Medical Center, Columbus, OH.

2008–present

• Director, Center for Cardiovascular and Pulmonary Research, The Research Institute at Nationwide Children’s Hospital

2007–2008

• Professor (tenured), Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, LA

2007–2008

• Co-Director Cardiovascular Center of Excellence, Louisiana State University Health Sciences Center, New Orleans, LA

2004–2007

• Associate Professor (tenured), Department of Pharmacology and Experimental Therapeutics, Louisiana State University Health Sciences Center, New Orleans, LA

2002–2004

• Associate Professor (tenured), Department of Physiology and Biophysics, University of Alabama Birmingham School of Medicine, Birmingham, AL

2001–2004

• Associate Scientist, Cell Adhesion and Matrix Research Center, University of Alabama Birmingham School of Medicine, Birmingham, AL

1998–2001

• Assistant Professor, Department of Physiology and Biophysics, University of Alabama Birmingham School of Medicine, Birmingham, AL

1997–1998

• Adjunct Assistant Professor - Molecular Biology Program, Loyola University Chicago School of Medicine, Maywood, IL

1994–1998

• Assistant Professor- Department of Physiology, Cardiovascular Research Center, Loyola University Chicago School of Medicine, Maywood, IL

1993–1994

• Instructor – Depart of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, GA

• Bevan AK; Hutchinson KR; Foust KD; Braun L; McGovern VL; Schmelzer L; Ward JG; Petruska JC; Lucchesi PA; Burghes AH; Kaspar BK. 2010. Early heart failure in the SMNDelta7 model of spinal muscular atrophy and correction by postnatal scAAV9-SMN delivery.  Human Molecular Genetics. Vol. 19, no. 20. (October 15): 3895.
• Monreal G; Youtz DJ; Phillips AB; Eyman ME; Gorr MW; Velten C; Lucchesi PA; Wold LE; Gerhardt MA. 2010. Right ventricular remodeling in restrictive ventricular septal defect.  Journal Of Molecular And Cellular Cardiology. Vol. 49, no. 4. (October 1): 699.
• Lord KC; Shenouda SK; McIlwain E; Charalampidis D; Lucchesi PA; Varner KJ. 2010. Oxidative stress contributes to methamphetamine-induced left ventricular dysfunction.  Cardiovascular Research. Vol. 87, no. 1 (July 1): 111.
• Hutchinson KR; Stewart JA Jr; Lucchesi PA. 2010. Extracellular matrix remodeling during the progression of volume overload-induced heart failure.  Journal Of Molecular And Cellular Cardiology. Vol. 48, no. 3 (March 1): 564.
• Katz PS, Trask AJ, Lucchesi PA. 2010. Progressive coronary Artery Remodeling in diabetic db/db mice [Abstract]. FASEB J: Experimental Biology [Peer Reviewed] (Published)
• Hutchinson KR, Lord KC, Guggilam A, Cismowski MJ, Lucchesi PA. 2010. Reversal of volume overload leads to restoration of LV structure and function [Abstract]. Myogenesis and Cardiac Repair: Keystone Symposium (Published)
• Trask AJ, Katz PS, Lucchesi PA. 2010. Inward coronary artery remodeling in established type II diabetic mice [Abstract]: AHA Council for High Blood Pressure Research [Peer Reviewed] (Forthcoming)
• Monreal G, Youtz DJ, Eyman ME, Phillips AB, Lucchesi PA, Wold LE, Gerhardt MA. 2010. Subclinical right ventricular remodeling in restrictive ventricular septal defect [Abstract]: Basic Cardiovascular Sciences Symposium [Peer Reviewed] (Forthcoming)
• Chicoine LG; Stewart JA Jr; Lucchesi PA. 2009. Is resveratrol the magic bullet for pulmonary hypertension?.  Hypertension. Vol. 54, no. 3 (September 1): 473.
• Katz PS; Trask AJ; Lucchesi PA. 2009. Curcuminoids: Spicing up sympathovagal tone.  Nutrition (Burbank, Los Angeles County, Calif.). Vol. 25, no. 7-8 (July 1): 879.
• Shenouda SK; Varner KJ; Carvalho F; Lucchesi PA. 2009. Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes.  Cardiovascular Toxicology. Vol. 9, no. 1 (March 1): 30.
• Souza-Smith FM, Katz PS, Lucchesi PA. 2009. Flow-induced outward remodeling in diabetic mice [Abstract]. FASEB J: Experimental Biology [Peer Reviewed] (Published)
• Stewart JA Jr; Lazartigues E; Lucchesi PA. 2008. The angiotensin converting enzyme 2/Ang-(1-7) axis in the heart: a role for MAS communication?.  Circulation Research. Vol. 103, no. 11 (November 21): 1197.
• Shenouda SK; Lord KC; McIlwain E; Lucchesi PA; Varner KJ. 2008. Ecstasy produces left ventricular dysfunction and oxidative stress in rats.  Cardiovascular Research. Vol. 79, no. 4 (September 1): 662.
• Su J; Lucchesi PA; Gonzalez-Villalobos RA; Palen DI; Rezk BM; Suzuki Y; Boulares HA; Matrougui K. 2008. Role of advanced glycation end products with oxidative stress in resistance artery dysfunction in type 2 diabetic mice.  Arteriosclerosis, Thrombosis, And Vascular Biology. Vol. 28, no. 8 (August 1): 1432.
• Hutchison, KS; Stewart, JA Jr; Lord, KC; Varner, KJ; Lucchesi, PA. 2008. Chronic volume overload alters cardiac fibroblast secretion collagen and matrix regulatory protein [Abstract]. EB2008 San Diego (Published)
• Stewart, JA Jr; Hutchinson, KJ; Lord, KC; Varner, KJ; Lucchesi, PA. 2008. Role of fibroblasts in diabetic cardiomyopathy [Abstract]. EB2008 San Diego (Published)
• Katz, PS; Souza, FM; Reed, RE; Lord, KC; Lucchesi, PA. 2008. A role for antiotensin and oxidative stress in diabetes-induced coronary artery remodeling [Abstract]. EB2008 San Diego (Published)
• Souza, FM; Katz, PS; Lord, KC; Potter, B; Vassallo, D; Lucchesi, PA. 2008. Hypertrophic remodeling of diabetic mesenteric resistance arteries is attenuated by Tempol and apocynin [Abstract]. EB2008 San Diego (Published)
• Rezk, BM; Lord, KC; Reed, RE; Hutchinson, KJ; Espinoza, C; McIlwain, E; El-Kak, AA; Varner, KJ; Lucchesi, PA. 2008. Beneficial effects of folic acid supplementation on the left ventricular volume overload [Abstract]. EB2008 San Diego (Published)
• Guggilam A; Haque M; Kerut EK; McIlwain E; Lucchesi P; Seghal I; Francis J. 2007. TNF-alpha blockade decreases oxidative stress in the paraventricular nucleus and attenuates sympathoexcitation in heart failure rats.  American Journal Of Physiology. Heart And Circulatory Physiology. Vol. 293, no. 1 (July 1): H599.
• Ryan TD; Rothstein EC; Aban I; Tallaj JA; Husain A; Lucchesi PA; Dell'Italia LJ. 2007. Left ventricular eccentric remodeling and matrix loss are mediated by bradykinin and precede cardiomyocyte elongation in rats with volume overload.  Journal Of The American College Of Cardiology. Vol. 49, no. 7 (February 20): 811.
• Hutchinson, KJ; Majumdar, D; Reed, RE; Varner, KJ; Dell'Italia, LJ; Lucchesi, PA. 2007. Chronic volume overload induces an anti-fibrotic cardiac fibroblast phenotype in rat hearts [Abstract]. EB2007 (Published)
• Katz, PS; Petra-Rocic, P; Souza, FM; Matrougui, K; Lord, KC; Lucchesi, PA. 2007. Increased oxidative stress modulates coronary artery remodeling and passive stiffness in db/db diabetic mice [Abstract]. EB2007 (Published)
• Su J; Palen DI; Lucchesi PA; Matrougui K. 2006. Mice lacking the gene encoding for MMP-9 and resistance artery reactivity.  Biochemical And Biophysical Research Communications. Vol. 349, no. 4 (November 3): 1177.
• McNicholas-Bevensee CM; DeAndrade KB; Bradley WE; Dell'Italia LJ; Lucchesi PA; Bevensee MO. 2006. Activation of gadolinium-sensitive ion channels in cardiomyocytes in early adaptive stages of volume overload-induced heart failure.  Cardiovascular Research. Vol. 72, no. 2 (November 1): 262.
• Rocic P; Rezk B; Lucchesi PA. 2006. PPAR-gamma agonists decrease hyperhomcysteinemia and cardiac dysfunction: new hope for ailing diabetic hearts?.  American Journal Of Physiology. Heart And Circulatory Physiology. Vol. 291, no. 1 (July 1): H26.
• Sato M; Cismowski MJ; Toyota E; Smrcka AV; Lucchesi PA; Chilian WM; Lanier SM. 2006. Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma.  Proceedings Of The National Academy Of Sciences Of The United States Of America. Vol. 103, no. 3 (January 17): 797.
• Sabri A; Lucchesi PA. 2006. ANG II and cardiac myocyte contractility: p38 is not stressed out!.  American Journal Of Physiology. Heart And Circulatory Physiology. Vol. 290, no. 1 (January 1): H72.
• Palen DI; Ouhtit A; Belmadani S; Lucchesi PA; Matrougui K. 2006. Hydrogen peroxide acts as relaxing factor in human vascular smooth muscle cells independent of map-kinase and nitric oxide.  Frontiers In Bioscience: A Journal And Virtual Library. Vol. 11 (January 1): 2526.
• Palen DI; Belmadani S; Lucchesi PA; Matrougui K. 2005. Role of SHP-1, Kv.1.2, and cGMP in nitric oxide-induced ERK1/2 MAP kinase dephosphorylation in rat vascular smooth muscle cells.  Cardiovascular Research. Vol. 68, no. 2 (November 1): 268.
• Rocic P; Lucchesi PA. 2005. NAD(P)H oxidases and TGF-beta-induced cardiac fibroblast differentiation: Nox-4 gets Smad.  Circulation Research. Vol. 97, no. 9 (October 28): 850.
• Rothstein EC; Lucchesi PA. 2005. Redox control of the cell cycle: a radical encounter.  Antioxidants & Redox Signaling. Vol. 7, no. 5-6 (May 1): 701.
• Hughie, HH; Rothstein, EC; Ryan, TD; Shenouda, S; Dell'Italia, LJ; Lucchesi, PA. 2005. Altered cardiac myocyte redox status is associated with the transition from compensated to decompensated heart failure in response to volume overload [Abstract]. Keystone Symposia, Steamboat Springs, CO. (April) (Published)
• Reed, RE; Hughie, HH; Dell'Italia, LJ; Lucchesi, PA. 2005. Increased peroxynitrite production is a key mediator of LV extracellular matrix remodeling in response to acute volume overload [Abstract]. Keystone Symposia, Steamboat Springs, CO. (April) (Published)
• Lord, KC; Reed, RE; Hicks, AR; Lucchesi, PA; Varner, KJ. 2005. Role of oxidative stress in methamphetamine-induced cardiac dysfunction [Abstract]. Keystone Symposia, Steamboat Springs, CO. (April) (Published)
• Lucchesi PA; Belmadani S; Matrougui K. 2005. Hydrogen peroxide acts as both vasodilator and vasoconstrictor in the control of perfused mouse mesenteric resistance arteries.  Journal Of Hypertension. Vol. 23, no. 3 (March 1): 571.
• Lucchesi PA; Sabri A; Belmadani S; Matrougui K. 2004. Involvement of metalloproteinases 2/9 in epidermal growth factor receptor transactivation in pressure-induced myogenic tone in mouse mesenteric resistance arteries.  Circulation. Vol. 110, no. 23 (December 7): 3587.
• Smiley LM; Camp TM; Lucchesi PA; Tyagi SC. 2004. Peroxisome proliferator ameliorates endocardial endothelial and muscarinic dysfunction in spontaneously hypertensive rats.  Antioxidants & Redox Signaling. Vol. 6, no. 2 (April 1): 367.
• Lucchesi PA. 2004. Rapamycin plays a new role as differentiator of vascular smooth muscle phenotype. focus on "The mTOR/p70 S6K1 pathway regulates vascular smooth muscle differentiation".  American Journal Of Physiology. Cell Physiology. Vol. 286, no. 3 (March 1): C480.
• Lucchesi PA. 2004. Growth hormone-releasing peptides and the heart: secretagogues or cardioprotectors?.  Cardiovascular Research. Vol. 61, no. 1 (January 1): 7.
• Rothstein, EC; Lucchesi, PA. 2004. Regulation of Na+/H+ exchange by reactive oxygen species. In The Cardiac Na+/H+ Exchanger. Edited by NS Dhalla & L Fliegel. Boston, MA: Kluwer Academic Publishers.
• Rocic P; Jo H; Lucchesi PA. 2003. A role for PYK2 in ANG II-dependent regulation of the PHAS-1-eIF4E complex by multiple signaling cascades in vascular smooth muscle.  American Journal Of Physiology. Cell Physiology. Vol. 285, no. 6 (December 1): C1437.
• Sabri A; Hughie HH; Lucchesi PA. 2003. Regulation of hypertrophic and apoptotic signaling pathways by reactive oxygen species in cardiac myocytes.  Antioxidants & Redox Signaling. Vol. 5, no. 6 (December 1): 731.
• Wei CC; Lucchesi PA; Tallaj J; Bradley WE; Powell PC; Dell'Italia LJ. 2003. Cardiac interstitial bradykinin and mast cells modulate pattern of LV remodeling in volume overload in rats.  American Journal Of Physiology. Heart And Circulatory Physiology. Vol. 285, no. 2 (August 1): H784.
• Tallaj J; Wei CC; Hankes GH; Holland M; Rynders P; Dillon AR; Ardell JL; Armour JA; Lucchesi PA; Dell'Italia LJ. 2003. Beta1-adrenergic receptor blockade attenuates angiotensin II-mediated catecholamine release into the cardiac interstitium in mitral regurgitation.  Circulation. Vol. 108, no. 2 (July 15): 225.
• Matrougui, K; Belmandi, S; Perez, J; Lucchesi, PA. 2003. Potential role of hydrogen peroxide as an endothelium derived hyperpolarization factor in human vascular smooth muscle cells [Abstract]. FASEB Summer Research Conference, Snowmass, CO. (July) (Published)
• Shastry S; Hayden MR; Lucchesi PA; Tyagi SC. 2003. Matrix metalloproteinase in left ventricular remodeling and heart failure.  Current Cardiology Reports. Vol. 5, no. 3 (May 1): 200.
• McRae-Bradford, CN; Christian, RA; Bereck, KH; Lucchesi, PA. 2003. Increased PAI-1 expression in spontaneously hypertensive rats prior to the onset of hypertension [Abstract]. XIV Annual InterAmerican Society for Hypertension Meeting. (April) (Published)
• Stewart JA Jr; Wei CC; Brower GL; Rynders PE; Hankes GH; Dillon AR; Lucchesi PA; Janicki JS; Dell'Italia LJ. 2003. Cardiac mast cell- and chymase-mediated matrix metalloproteinase activity and left ventricular remodeling in mitral regurgitation in the dog.  Journal Of Molecular And Cellular Cardiology. Vol. 35, no. 3 (March 1): 311.
• Rothstein EC; Byron KL; Reed RE; Fliegel L; Lucchesi PA. 2002. H(2)O(2)-induced Ca(2+) overload in NRVM involves ERK1/2 MAP kinases: role for an NHE-1-dependent pathway.  American Journal Of Physiology. Heart And Circulatory Physiology. Vol. 283, no. 2 (August 1): H598.
• Hunton DL; Lucchesi PA; Pang Y; Cheng X; Dell'Italia LJ; Marchase RB. 2002. Capacitative calcium entry contributes to nuclear factor of activated T-cells nuclear translocation and hypertrophy in cardiomyocytes.  The Journal Of Biological Chemistry. Vol. 277, no. 16 (April 19): 14266.
• Byron KL; Lucchesi PA. 2002. Signal transduction of physiological concentrations of vasopressin in A7r5 vascular smooth muscle cells. A role for PYK2 and tyrosine phosphorylation of K+ channels in the stimulation of Ca2+ spiking.  The Journal Of Biological Chemistry. Vol. 277, no. 9 (March 1): 7298.
• Rocic P; Griffin TM; McRae CN; Lucchesi PA. 2002. Altered PYK2 phosphorylation by ANG II in hypertensive vascular smooth muscle.  American Journal Of Physiology. Heart And Circulatory Physiology. Vol. 282, no. 2 (February 1): H457.
• Rothstein, EC; Brower, GL; Dell'Italia, LJ; Lucchesi, PA. 2002. Altered cardiomyocyte function during the progression of volume overload heart failure [Abstract]. FASEB J. Vol. 16: A35. (Published)
• Perez, J; Rocic, P; Lucchesi, PA. 2002. A role for PYK2 in PDGF-induced vascular smooth muscle proliferation [Abstract]. FASEB J. Vol. 16: A388. (Published)
• Dell'Italia LJ; Rocic P; Lucchesi PA. 2002. Use of angiotensin-converting enzyme inhibitors in patients with diabetes and coronary artery disease.  Current Problems In Cardiology. Vol. 27, no. 1 (January 1): 6.
• Bernal, JM; Perry, GJ; Dell'Italia, LJ; Tallaj, JA; Bradley, WE; Murphy-Ullrich, PA; Lucchesi, PA; Berecek, KH. 2002. Cardiac remodeling and systolic function in the streptozotocin (STZ)-diabetic rat [Abstract]. FASEB J. Vol. 16: A113. (Published)
• McRae, CN; Berecek, KH; Grostick, L; Lucchesi, PA. 2002. Increased MMP expression by captopril treatment reduces early left ventrical collagen deposition in spontaneously hypertensive rats [Abstract]. FASEB J. Vol. 16: A92. (Published)
• Kuruganti PA; Wurster RD; Lucchesi PA. 2002. Mitogen activated protein kinase activation and oxidant signaling in astrocytoma cells.  Journal Of Neuro-Oncology. Vol. 56, no. 2 (January 1): 109.
• Ryan, TD; Khatri, G; Dell'Italia, LJ; Lucchesi, PA. 2002. Dynamic extracellular matrix remodeling during the progression of volume overload-induced heart failure [Abstract]. FASEB J. Vol. 16: A256. (Published)
• Reed, RE; Sabri, A; Lucchesi, PA. 2002. H202-induced cardiomyocyte dysfunction involves sarcomeric disassembly [Abstract]. FASEB J. Vol. 16: AA423. (Published)
• Wei S; Rothstein EC; Fliegel L; Dell'Italia LJ; Lucchesi PA. 2001. Differential MAP kinase activation and Na(+)/H(+) exchanger phosphorylation by H(2)O(2) in rat cardiac myocytes.  American Journal Of Physiology. Cell Physiology. Vol. 281, no. 5 (November 1): C1542.
• Rocic P; Lucchesi PA. 2001. Down-regulation by antisense oligonucleotides establishes a role for the proline-rich tyrosine kinase PYK2 in angiotensin ii-induced signaling in vascular smooth muscle.  The Journal Of Biological Chemistry. Vol. 276, no. 24 (June 15): 21902.
• Bayer AL; Ferguson AG; Lucchesi PA; Samarel AM. 2001. Pyk2 expression and phosphorylation in neonatal and adult cardiomyocytes.  Journal Of Molecular And Cellular Cardiology. Vol. 33, no. 5 (May 1): 1017.
• Rocic, P; Lucchesi, PA. 2001. PYK2 antisense inhibits angiotensin II-induced protein synthesis through ERK1/2 MAP kinases and Akt in vascular smooth muscle [Abstract]. FASEB J. Vol. 15: A488. (Published)
• McRae, CN; Lucchesi, PA; Berecek, KH. 2001. Differential ERK1/2 MAP kinase activation by angiotensin II in SHR and WKY cardiac fibroblasts [Abstract]. FASEB J. Vol. 15: A486. (Published)
• Rocic P; Govindarajan G; Sabri A; Lucchesi PA. 2001. A role for PYK2 in regulation of ERK1/2 MAP kinases and PI 3-kinase by ANG II in vascular smooth muscle.  American Journal Of Physiology. Cell Physiology. Vol. 280, no. 1 (January 1): C90.
• Wei, S; Anderson, PA; Lucchesi, PA. 2001. Altered regulation of MAP kinases by oxidative stress in adult cardiac myocytes during the development of pressure-overload hypertrophy [Abstract]. FASEB J. Vol. 15: A502. (Published)
• Perry, GJ; Mori, T; Wei, CC; Xu, XY; Chen, YF; Oparil, S; Lucchesi, P; Dell'Italia, LJ. 2001. Genetic variation in angiotensin-converting enzyme does not prevent development of cardiac hypertrophy or upregulation of angiotensin II in response to aortocaval fistula.  Circulation. Vol. 103: 1012.
• Sun, JZ; Oparil, S; Lucchesi, PA; Thompson, JA; Chen, YF. 2001. Tyrosine kinase receptor activation inhibits NPR-C in lung arterial smooth muscle cells.  Am J Physiol Lung Cell Mol Physiol. Vol. 281: 155-163.
• Govindarajan G; Eble DM; Lucchesi PA; Samarel AM. 2000. Focal adhesion kinase is involved in angiotensin II-mediated protein synthesis in cultured vascular smooth muscle cells.  Circulation Research. Vol. 87, no. 8 (October 13): 710.
• Arora-Kuruganti P; Lucchesi PA; Wurster RD. 1999. Proliferation of cultured human astrocytoma cells in response to an oxidant and antioxidant.  Journal Of Neuro-Oncology. Vol. 44, no. 3 (January 1): 213.
• Sabri A; Govindarajan G; Griffin TM; Byron KL; Samarel AM; Lucchesi PA. 1998. Calcium- and protein kinase C-dependent activation of the tyrosine kinase PYK2 by angiotensin II in vascular smooth muscle.  Circulation Research. Vol. 83, no. 8 (October 19): 841.
• Sabri A; Byron KL; Samarel AM; Bell J; Lucchesi PA. 1998. Hydrogen peroxide activates mitogen-activated protein kinases and Na+-H+ exchange in neonatal rat cardiac myocytes.  Circulation Research. Vol. 82, no. 10 (June 1): 1053.
• Eble DM; Qi M; Waldschmidt S; Lucchesi PA; Byron KL; Samarel AM. 1998. Contractile activity is required for sarcomeric assembly in phenylephrine-induced cardiac myocyte hypertrophy.  The American Journal Of Physiology. Vol. 274, no. 5 Pt 1 (May 1): C1226.
• Wang H; Silva NL; Lucchesi PA; Haworth R; Wang K; Michalak M; Pelech S; Fliegel L. 1997. Phosphorylation and regulation of the Na+/H+ exchanger through mitogen-activated protein kinase.  Biochemistry. Vol. 36, no. 30 (July 29): 9151.
• Phan VN; Kusuhara M; Lucchesi PA; Berk BC. 1997. A 90-kD Na(+)-H+ exchanger kinase has increased activity in spontaneously hypertensive rat vascular smooth muscle cells.  Hypertension. Vol. 29, no. 6 (June 1): 1265.
• Lucchesi PA; Bell JM; Willis LS; Byron KL; Corson MA; Berk BC. 1996. Ca(2+)-dependent mitogen-activated protein kinase activation in spontaneously hypertensive rat vascular smooth muscle defines a hypertensive signal transduction phenotype.  Circulation Research. Vol. 78, no. 6 (June 1): 962.
• Lucchesi PA; Berk BC. 1995. Regulation of sodium-hydrogen exchange in vascular smooth muscle.  Cardiovascular Research. Vol. 29, no. 2 (February 1): 172.
• Lucchesi PA; DeRoux N; Berk BC. 1994. Na(+)-H+ exchanger expression in vascular smooth muscle of spontaneously hypertensive and Wistar-Kyoto rats.  Hypertension. Vol. 24, no. 6 (December 1): 734.
• Lucchesi PA; Sweadner KJ. 1991. Postnatal changes in Na,K-ATPase isoform expression in rat cardiac ventricle. Conservation of biphasic ouabain affinity.  The Journal Of Biological Chemistry. Vol. 266, no. 14 (May 15): 9327.
• Lucchesi PA; Scheid CR; Romano FD; Kargacin ME; Mullikin-Kilpatrick D; Yamaguchi H; Honeyman TW. 1990. Ligand binding and G protein coupling of muscarinic receptors in airway smooth muscle.  The American Journal Of Physiology. Vol. 258, no. 4 Pt 1 (April 1): C730.
• Lucchesi PA; Romano FD; Scheid CR; Yamaguchi H; Honeyman TW. 1989. Interaction of agonists and selective antagonists with gastric smooth muscle muscarinic receptors.  Naunyn-Schmiedeberg's Archives Of Pharmacology. Vol. 339, no. 1-2 (January 1): 145.
• Lucchesi PA; Cooney RA; Mangsen-Baker C; Honeyman TW; Scheid CR. 1988. Assessment of transport capacity of plasmalemmal Ca2+ pump in smooth muscle.  The American Journal Of Physiology. Vol. 255, no. 2 Pt 1 (August 1): C226.
• Lucchesi PA; Scheid CR. 1988. Effects of the anti-calmodulin drugs calmidazolium and trifluoperazine on 45Ca transport in plasmalemmal vesicles from gastric smooth muscle.  Cell Calcium. Vol. 9, no. 2 (April 1): 87.
• Lucchesi P; Carraway M; Marinus MG. 1986. Analysis of forward mutations induced by N-methyl-N'-nitro-N-nitrosoguanidine in the bacteriophage P22 mnt repressor gene.  Journal Of Bacteriology. Vol. 166, no. 1 (April 1): 34.
• Lucchesi, P, Presenter. 2000. Reactive oxygen species and cardiac remodeling. Plenary Speaker, American Heart Association Scientific Sessions. Washington, DC.
• Lucchesi, P, Presenter. 2002. NHE-1 in cardiac myocytes. Experimental Biology. New Orleans, LA.
• Lucchesi, P, Presenter. 2010. Diabetes and the Heart: The Biggest Loser? Keynote Speaker, Experimental Biology. Anaheim, CA.
• Lucchesi, P, Presenter. 2001. Regulation of Na+/H+ exchange in myoctyes. International Society for Heart Research.
• Lucchesi, P, Poster Presenter. 2005. Molecular mechanisms of heart failure. Keystone Symposia. Steamboat Springs, CO.
• Lucchesi, P, Presenter. 1999. Activation of Na+/H+ exchange in cardiac myocytes. Plenary Lecture, International Society for Heart Research. Winnepeg, Manitoba, Canada.
• Lucchesi, P, Presenter. 1988. Indentification of muscarinic cholinergic receptors in trachael smooth muscle. FASEB Meeting. Philadelphia, PA.
• Lucchesi, P, Presenter. 2001. PI 3-kinase signaling in vascular smooth muscle. Experimental Biology. Washington, DC.
• Lucchesi, P, Presenter. 2002. Mechanisms of oxident stress induced heart failure. AHA Scientific Conference on Advances in Molecular and Cellular Mechanisms of Heart Failure. Salt Lake City, UT.
• Lucchesi, P, Presenter. 1987. Regulation of Ca2+ -ATPase activation in gastric smooth muscle. FASEB Meeting. Washington.
• Lucchesi, P, Presenter. 1992. Developmental expressions Na+, K+, -ATPase isoforms in post natal rat hearts. Biophysical Society Meeting. Baltimore, MD.
• Lucchesi, P, Presenter. 2004. Regulation of the myocardial remodeling by matrix metalloproteinases. Experimental Biology. Washington, DC.
• Lucchesi, P, Presenter. 2000. Regulation of vascular smooth muscle cells. FASEB Summer Research Conference. Snowmass, CO.
• Lucchesi, P, Presenter. 1997. Oxidative stress and sarcomeric organization in cardiac myocytes. American Heart Association Scientific Sessions.
• Lucchesi, P, Presenter. 2002. Cardiac fibroblasts and heart failure. Experimental Biology. New Orleans, LA.
• Lucchesi, P, Presenter. 1984. Analysis of MNNG induced mutations in bacteria. Mutagenesis Society Meeting, University of Connecticut. Storrs, CT.
• Lucchesi, P, Presenter. 2003. Cytokines and vascular smooth muscle. AHA Scientific Session. Orlando, FL.
• Lucchesi, P, Presenter. 2001. PYK2 and vascular smooth muscle growth: Choosy receptors pick PYK2. Gordon Research Conference "Angiotension". Ventura, CA.