Nephrology Research and Innovation :: Nationwide Children's Hospital

Nephrology Research and Innovation

In addition to providing outstanding clinical care, members of the Section of Nephrology conduct research to improve patient outcomes. Read below to get the latest research updates.

Members of the Section of Nephrology also participate in the Nephrology and Urology Research Affinity Group (NURAG). NURAG is composed of medical faculty, residents and fellows from the Nephrology and Urology programs at Nationwide Children’s Hospital. NURAG also includes members of The Research Institute at Nationwide Children’s whose research projects focus on the fields of nephrology, urology and associated disciplines.

Get the Latest

Reducing Fractures in Infants with Osteogenesis Imperfecta
Intravenous pamidronate to reduce fracture rates in OI may offer a safe, effective therapeutic option.

Infection Susceptibility Depends on Kidney pH Balance and Key Enzyme
Research suggests that manipulating the kidneys’ homeostasis-related proteins may have therapeutic potential for pyelonephritis patients.

A Crash Course in Urinary Tract Self-Defense
Learn about the mechanisms behind the innate immune response to UTI and pyelonephritis.

New Membranes May Make Continuous Renal Replacement Therapy Safer
Preliminary research suggests the use of different membranes may reduce the risk of severe hypotensive episodes among patients initiating continuous renal replacement therapy.

Connecting Kidney Stones to Bone Density
Kidney stones are increasingly common among children. Now, nephrologists must consider what this means for patients’ bone health.

When Vitamin D Doesn’t Work for Rickets
Despite late initiation of proper therapy, physicians improved one case of rickets-induced genu valgum from 24 degrees to 4.

Urinary Tract Beta Defensin vs. E. Coli
While researching the role of beta defensin-1 against E. coli in the lower urinary tract, scientists identified two other defensins.

Regulating Urinary Tract Sterility
The discoverers of the potent antimicrobial peptide, RNase 7, further our understanding of the urinary tract’s self-protection.

Predicting Kidney Damage Risk
Studies of the megabladder mouse model could help researchers predict the severity of urinary tract obstruction in children.

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