Nehal A. Parikh, DO :: Nationwide Children’s Hospital, Columbus, Ohio

Nehal A. Parikh, DO, MS

Nehal A. Parikh, DO, MS

Center for Perinatal Research
Principal Investigator

Neonatology
Physician Team

Neonatology Fellowship
Faculty

Parikh Lab
Principal Investigator

Contact Information

Neonatology
700 Children's Dr
Columbus, OH 43205 [ map ]
PH: (614) 722-4559
FX: (614) 722-4541
Center for Perinatal Research
575 Children's Crossroad
Columbus, Ohio 43215 [ map ]
PH: (614) 355-5724
FX: (614) 722-5899

Location Information for Patients

Main Campus

Biography

Nehal Parikh, DO, MS joined the Section of Neonatology as an Associate Professor of Pediatrics and Principal Investigator in the Center for Perinatal Research at Nationwide Children’s Hospital in January 2011. Dr. Parikh completed his pediatrics residency at Winthrop University Hospital of State University of New York at Stony Brook and fellowship in neonatal-perinatal medicine at Thomas Jefferson University Hospital in Philadelphia. He completed received an M.S. degree in Clinical & Translational Research from the University of Texas Health Science Center at Houston, where he was on faculty for 8 years. Dr. Parikh’s lab utilizes and develops advanced MRI methods (diffusion, functional, spectroscopy) for neonates to enable early diagnosis/prediction of sensorimotor, cognitive, and behavioral impairments in very preterm (≤32 weeks gestational age) infants. These impairments result from commonly observed perinatal brain injury and delayed brain maturation that are frequently observed in more than 50% of very preterm infants. Early diagnosis within 3 months of birth can reduce the current delays in diagnosis of up to 3 years and facilitate targeted early intervention clinical therapies and novel neuroprotective research interventions.

Gender:

  • Male

Languages Spoken:

  • English
  • Gujarati

Research Interests

Research Center:

Areas of Interest:

  • Perinatal brain injury and delayed brain development are leading contributors of neurodevelopmental impairments in very preterm infants. Dr. Parikh’s long-term goal is to improve the quality of life of high-risk neonates through early diagnosis and treatment of neurodevelopmental impairments. His short-term goal is to apply and develop advanced MRI tools (e.g., diffusion and functional MRI) for neonates to enable early diagnosis of cognitive, behavioral, and sensorimotor impairments. Our recent focus has turned to understanding the epidemiology of the frequently encountered diffuse excessive high signal intensity (DEHSI) abnormality in very preterm infants. We have developed a digital atlas to automatically detect such abnormalities and are planning to follow a multicenter cohort of very preterm infants into school age to determine their long-term functional significance. Data from our pilot study suggest that DEHSI is associated with cognitive and language delays at 2 years of age. We have also developed advanced MRI biomarkers at term corrected age to accurately predict sensorimotor impairments in very preterm infants.

Education and Training

Medical School

  • New York College of Osteopathic Medicine of New Yo
    Date Completed: 05/31/1996

Residency

  • SUNY Stony Brook School of Medicine
    Date Completed: 06/30/1999

Fellowship

  • Jefferson Medical College Hospital
    Date Completed: 06/30/2002

Graduate School

  • University of Texas Medical School at Houston
    Date Completed: 12/15/2007

Department:

  • Pediatrics

Section:

  • Neonatology

Specialty:

  • Neonatal-Perinatal Medicine

Date of Appointment at Nationwide Children’s Hospital:

  • 03/31/2011

Publications

  • He,Lili; Parikh,Nehal,A. 2015. Aberrant Executive and Frontoparietal Functional Connectivity in Very Preterm Infants With Diffuse White Matter Abnormalities.  Pediatric neurology. Vol. 53, no. 4. (October): 330-337.
  • Parikh,Nehal,A; Kennedy,Kathleen,A; Lasky,Robert,E; Tyson,Jon,E. 2015. Neurodevelopmental Outcomes of Extremely Preterm Infants Randomized to Stress Dose Hydrocortisone.  PloS one. Vol. 10, no. 9. (August): ee0137051.
  • Shankaran S, Laptook AR, Pappas A, et al. 2014. Effect of depth and duration of cooling on deaths in the NICU among neonates with hypoxic ischemic encephalopathy: a randomized clinical trial.  Journal of the American Medical Association. Vol. 312, no. 24. (December): 2629-39.
  • Pogribna U, Burson K, Lasky RE, Narayana PA, Evans PW, Parikh NA. 2014. Role of Diffusion Tensor Imaging (DTI) as an Independent Predictor of Cognitive and Language Development in Extremely Preterm Infants.  American Journal of Neuroradiology. Vol. 35, no. 4. (April): 790-6.
  • Kaur S, Powell S, He L, Pierson C, Parikh NA. 2014. Reliability and Repeatability of Quantitative Tractography Methods for Mapping Structural White Matter Connectivity in Preterm and Term Infants at Term-Equivalent Age.  PLOS ONE. Vol. 9, no. 1. (January): ee85807.
  • Bapat R, Narayana PA, Zhou Y, Parikh NA. 2014. Magnetic Resonance Spectroscopy at Term Equivalent Age in Extremely Preterm Infants: Association with Cognitive and Language Development.  Pediatric Neurology. Vol. 51, no. 1. (January): 53-9.
  • He L, Parikh NA. 2013. Atlas-Guided Quantification of White Matter Signal Abnormalities on Term-Equivalent Age MRI in Very Preterm Infants: Findings Predict Language and Cognitive Development at Two Years of Age.  PLOS ONE. Vol. 8, no. 12. (December): ee85475.
  • Parikh NA, He L, Bonfante-Mejia E, Hochhauser L, Wilder PE, Burson K, Kaur S. 2013. Automatically Quantified Diffuse Excessive High Signal Intensity on MRI Predicts Cognitive Development in Preterm Infants.  PEDIATRIC NEUROLOGY. Vol. 49, no. 6. (December): 424-430.
  • Pogribna U, Yu X, Burson K, Zhou Y, Lasky R, Narayana P, Parikh NA. 2013. Perinatal Clinical Antecedents of White Matter Microstructural Abnormalities on Diffusion Tensor Imaging in Extremely Preterm Infants.  PLOS ONE. Vol. 8, no. 8. (August): ee72974.
  • Parikh NA, Lasky RE, Kennedy KA, McDavid G,Tyson JE. 2013. Perinatal Factors and Regional Brain Volume Abnormalities at Term in a Cohort of Extremely Low Birth Weight Infants.  PLOS ONE. Vol. 8, no. 5. (May): ee62804.
  • Parikh NA, Kennedy KA, Lasky RE, McDavid GE, Tyson JE. 2013. Pilot Randomized Trial of Hydrocortisone in Ventilator-Dependent Extremely Preterm Infants: Effects on Regional Brain Volumes.  JOURNAL OF PEDIATRICS. Vol. 162, no. 4. (April): 685-690.
  • He L, Parikh NA. 2013. Automated detection of white matter signal abnormality using T2 relaxometry: Application to brain segmentation on term MRI in very preterm infants.  NEUROIMAGE. Vol. 64, no. January: 328-340.
  • Pogribna U, Yu X, Burson K, Lasky RE, Narayana PA, Parikh NA. 2013. Antecedents of Diffusion Tensor MRI Abnormalities at Term Equivalent Age in a Cohort of Extremely Preterm Infants.  PLoS ONE. Vol. 8, no. 8. (January): ee792974.
  • Ambalavanan N, Carlo WA, Tyson JE, Langer JC, Walsh MC, Parikh NA, Das A, Van Meurs KP, Shankaran S, Stoll BJ, Higgins RD. 2012. Outcome Trajectories in Extremely Preterm Infants.  PEDIATRICS. Vol. 130, no. 1. (July): E115-E125.
  • Moorehead PA, Martin EM, Shepherd EG, Parikh NA, Reagan PB, Gardner W, Yeates KO, Nelin LD. 2012. Factors Associated with Survival of <27 Week Infants in an All-Referral Neonatal Intensive Care Unit.  Journal of Neonatal Perinatal Medicine. Vol. 5, no. (2). (May): 105-11.
  • Lasky RE, Church MW, Orlando MS, Morris BH, Parikh NA, Tyson JE, McDavid GE, Oh W, Stevenson DK, Van Meurs KP, Guillet R, Phelps DL. 2012. The Effects of Aggressive Versus Conservative Phototherapy on the Brainstem Auditory Evoked Responses of Extremely Low Birth Weight Infants.  Pediatric Research 2012 PMID22289854. Vol. 71(1):, no. January: 77-84.
  • Beauchamp MS, Beurlot MR, Fava E, Nath AR Parikh NA, Saad ZS, Bortfeld H, Oghalai JS. 2011. The Developmental Trajectory of Brain-Scalp Distance from Birth through Childhood: Implications for Functional Neuroimaging.  PLOS ONE. Vol. 6, no. 9. (September): ee24981.
  • Shankaran S, Pappas A, McDonald SA, Laptook AR, Bara R, Ehrenkranz RA, Tyson JE, Goldberg R, Donovan EF, Fanaroff AA, Das A, Poole WK, Walsh M, Higgins RD, Welsh C, Salhab W, Carlo WA, Poindexter B, Stoll BJ, Guillet R, Finer NN, Stevenson DK, Bauer CR. 2011. Predictive Value of an Early Amplitude Integrated Electroencephalogram and Neurologic Examination.  Pediatrics. Vol. 128, no. 1. (July): e112-20.
  • Yu X, Zhang Y, Lasky RE, Datta S, Parikh NA, Narayana PA. 2010. Comprehensive Brain MRI Segmentation in High Risk Preterm Newborns.  PLOS ONE. Vol. 5, no. 11. (November): ee13874.
  • Lee HC, Green C, Hintz SR, Tyson JE, Parikh NA, Langer J, Gould JB. 2010. Prediction of Death for Extremely Premature Infants in a Population-Based Cohort.  PEDIATRICS. Vol. 126, no. 3. (September): E644-E650.
  • Parikh NA, Lasky RE, Garza CN, Bonfante-Mejia E, Shankaran S, Tyson JE. 2009. Volumetric and anatomical MRI for hypoxic-ischemic encephalopathy: relationship to hypothermia therapy and neurosensory impairments.  JOURNAL OF PERINATOLOGY. Vol. 29, no. 2. (February): 143-149.
  • Lasky RE, Parikh NA, Williams AL, Padhye NS, Shankaran S. 2009. Changes in the PQRST Intervals and Heart Rate Variability Associated with Rewarming in Two Newborns Undergoing Hypothermia Therapy.  NEONATOLOGY. Vol. 96, no. 2. (January): 93-95.
  • Mietzsch U, Parikh NA, Williams AL, Shankaran S, Lasky RE. 2008. Effects of hypoxic-ischemic encephalopathy and whole-body hypothermia on neonatal auditory function: A pilot study.  AMERICAN JOURNAL OF PERINATOLOGY. Vol. 25, no. 7. (August): 435-441.
  • Tyson JE, Parikh NA, Langer J, Green C, Higgins RD. 2008. Intensive care for extreme prematurity - Moving beyond gestational age.  NEW ENGLAND JOURNAL OF MEDICINE. Vol. 358, no. 16. (April): 1672-1681.
  • Parikh NA, Lasky RE, Kennedy KA, Moya FR, Hochhauser L, Romo S, Tyson JE. 2007. Postnatal dexamethasone therapy and cerebral tissue volumes in extremely low birth weight infants.  PEDIATRICS. Vol. 119, no. 2. (February): 265-272.
  • Katsetos CD, Parikh NA, Fritz KI, Legido A, Delivoria-Papadopoulos M, Mishra OP. 2006. Effect of 7-nitroindazole sodium on the cellular distribution of neuronal nitric oxide synthase in the cerebral cortex of hypoxic newborn piglets.  NEUROCHEMICAL RESEARCH. Vol. 31, no. 7. (July): 899-906.
  • Parikh N, Tyson J. 2006. Viability, Treatment, and Outcome at 18-22 Months for Extremely Premature Infants.  NICHD Neonatal Research Network. Vol. 59, no. May: en/a.
  • Gupta RK, Hasan KM, Trivedi R, Pradhan M, Das V, Parikh NA, Narayana PA. 2005. Diffusion tensor imaging of the developing human cerebrum.  JOURNAL OF NEUROSCIENCE RESEARCH. Vol. 81, no. 2. (July): 172-178.
  • Lasky RE, Luck ML, Parikh NA, Laughlin NK. 2005. The effects of early lead exposure on the brains of adult rhesus monkeys: A volumetric MRI study.  TOXICOLOGICAL SCIENCES. Vol. 85, no. 2. (June): 963-975.
  • Parikh N. 2004. The Brain. In High Risk. A Handbook for the Aftercare of Premature Infants. Edited by Bradt P, Herbert D. Houston: Savage Design.
  • Parikh NA, Locke RG, Chidekel A, Leef KH, Emberger J, Paul DA, Stefano JL. 2004. Effect of inhaled corticosteroids on markers of pulmonary inflammation and lung maturation in preterm infants with evolving chronic lung disease.  journal of the American Osteopathic Association. Vol. 104, no. 3. (March): 114-120.
  • Sorrentino DF, Fritz KI, Haider SH, Parikh, NA, Delivoria-Papadopoulos M, Mishra OP. 2004. Nitric Oxide Mediated Modification of the Glycine Binding Site of the NMDA Receptor during Hypoxia in the Cerebral Cortex of the Newborn Piglet.  Neurochem Res. Vol. 29, no. 2. (January): 455-459.
  • Parikh NA, Katsetos CD, Ashraf QM, Haider SH, Legido A, Delivoria-Papadopoulos M, Mishra OP. 2003. Hypoxia-induced caspase-3 activation and DNA fragmentation in cortical neurons of newborn piglets: Role of nitric oxide.  NEUROCHEMICAL RESEARCH. Vol. 28, no. 9. (September): 1351-1357.
  • Katsetos CD, Del Valle L, Geddes JF, Assimakopoulou M, Legido A, Boyd JC, Balin B. Parikh NA, Maraziotis T, de Chadarevian JP, Varakis JN, Matsas R, Spano A, Frankfurter A, Herman MM, Khalili K. 2001. Aberrant Localization of the Neuronal Class III Beta-tubulin in Astrocytomas.  Archives of Pathology and Laboratory Medicine. Vol. 125, no. 5. (May): 613-24.
  • Parikh, N.A., Katsetos, C.D., Fritz, K.I., Legido, A., and Mishra, O.P. Neuronal Nitric Oxide Synthase Expression Following Hypoxia in the Cerebral Cortex of Newborn Piglets. Pediatr Res. 51(4):461A, 2002.
  • Gupta, R.K., Hasan, K.M., Trivedi, R., Kanabar, B., Pradhan, M., Das, V., Parikh, N.A., and Narayana, P.A. Diffusion Tensor Imaging of the Developing Human Cerebrum. J Neurosci Res. 2005;81(2):172-178. PubMed ID: 15931676
  • Tyson, J.E., Parikh, N.A., Langer, J., Green, C., Higgins, R., for the NICHD Neonatal Research Network. Intensive Care for Extreme Prematurity – Moving Beyond Gestational Age. N Engl J Med. 2008;358(16):1672-81. PubMed ID: 18420500
  • Mietzsch, U., Parikh, N.A., Williams, A.L., Shankaran, S., and Lasky, R.E. Effects of Hypoxic-Ischemic Encephalopathy and Whole-Body Hypothermia on Neonatal Auditory Function: A Pilot Study. Am J of Perinatol. 2008;25(7):435-41. PubMed ID: 18720323
  • Parikh, N.A., Fritz K.I., Zhu, A., Mishra, O.P., and Delivoria-Papadopoulos, M. Effect of Neuronal Nitric Oxide Synthase (nNOS) Inhibition on DNA Fragmentation in Neuronal Nuclei During Hypoxia in Newborn Piglets. Pediatr Res. 49(4):45A, 2001.
  • Parikh, N.A., Lasky, R.E., Tyson, J.E., Kennedy, K.A., Zhang, Y., and Yu, X. Does Low Dose Hydrocortisone Improve Volumetric MRI Measures of Cerebral Growth in Extremely Low Birth Weight (ELBW) Infants at High Risk for Bronchopulmonary Dysplasia (BPD)?: A Randomized Trial. E-PAS 2009:Late-Breaker Platform.
  • McGowan, J.E., Zubrow, A.B., Parikh, N.A., and Zhu, A. Mechanism of Cerebral Oxidant Injury During Hypoglycemia and Hypoxia. Pediatr Res. 49(4):351A, 2001.
  • Parikh, N.A., Lasky, R.E., Tyson, J.E., Moya F.R., and Kennedy, K.A. Effects of Postnatal Dexamethasone on Cerebral Tissue Volumes in Extremely Low Birth Weight Infants. PAS 2005:57:1505A.
  • Ambalavanan, N. and GDB Subcommittee for the NICHD Neonatal Research Network. Outcome Trajectories in Extremely Low Birth Weight (ELBW) Infants. E-PAS 2009:4765.3.
  • Legido, A., Taylor, M.L., Geddes, J.F., Kaleyias, J.M., Parikh, N.A., Zanelli, S.A., de Chadarevian, J.P., and Katsetos, C.D. Decreased Immunoreactivity of Calbindin-D28K in Cerebellar Purkinje Cells of Children with Hypoxic/ Ischemic Encephalopathy. Annals of Neurology. 50(3S):S129, 2001.
  • Katsetos, C.D., Parikh, N.A., Fritz, K.I., Legido, A., Delivoria-Papadopoulos, M., and Mishra, O.P. Effect of 7-Nitroindazole Sodium on the Cellular Distribution of Neuronal Nitric Oxide Synthase in the Cerebral Cortex of Hypoxic Newborn Piglets. Neurochem Res. 2006;31(7):899-906. PubMed ID: 16804757
  • Zhang, Y., Yu, X., Lasky, R.E., Datta, S., Parikh, N.A., and Narayana, P.A. Comprehensive Brain MRI Segmentation in High Risk Preterm Newborns. PLoS One. 2010;5(11): e13874. PubMed ID: 21079730
  • Parikh, N.A., Ashraf, Q.M., Legido, A., Chadarevian, J.P., and Katsetos, C.D. Expression of Neuronal Nitric Oxide Synthase during Hypoxia in the Cerebellum of Newborn Piglets." Pediatr Res. 49(4):442A, 2001.
  • Lasky, R.E., Luck, M.L., Parikh, N.A., and Laughlin, N.K. The Effects of Early Lead Exposure on the Brains of Adult Rhesus Monkeys: A Volumetric MRI Study. Toxicol Sci. 2005;85(2):963-975. PubMed ID: 15788724
  • Parikh, N., Tyson, J., Kennedy, K., Yu, X., Zhang, Y., Shukla, R., Narayana, P., and Lasky, R. Perinatal Predictors of MRI Brain Volume Abnormalities at Term in Extremely Low Birth Weight (ELBW) Infants. E-PAS 2010:3746.501.
  • Fritz, K.I., Parikh, N.A., Zhu, A., Mishra, O.P., and Delivoria-Papadopoulos, M. Effect of Moderate Hypocapnic Ventilation on Neuronal Nuclear Ca++-Influx in the Cerebral Cortex of Newborn Piglets. Pediatr Res. 49(4):372A, 2001.
  • Lee, H.C., Green, C., Hintz, S.R., Tyson, J.E., Parikh, N.A., Langer, J., Gould, J.B. Prediction of Mortality for Extremely Premature Infants in a Population Based Cohort. Pediatrics. Sept. 2010;126(3):e644-50. PubMed ID: 20713479
  • Ramirez, M.M., Bertles, A., Parikh, N., Blackwell, S., and Tyson, J.E. Parental wishes, resuscitation decisions, and prognostic estimates at 22-24 wks gestation. Am J Obstet Gynecol 2008 SMFM meeting supplement. Am J Obstet Gynecol. 199(6); Supplement A: 219, p S72; 2008.
  • Parikh, N.A., Locke, R.L., Paul, D.A., Chidekel, A., Leef, K., Emberger, J., and Stefano, J.L. The Effect of Inhaled Corticosteroids on Markers of Pulmonary Inflammation and Lung Maturation in Preterm Infants with Evolving Chronic Lung Disease. J Am Osteopath Assoc. 2004;104(3):114-120. PubMed ID: 15083986
  • Parikh, N.A., Lasky, R.E., Tyson, J.E., Moya F.R., and Kennedy, K.A. Effects of Postnatal Dexamethasone on Brain Component Volumes in Extremely Low Birth Weight Infants. J Investig Med. 53(1):S291, 2005.
  • Hirsch, D., Parikh, N., and Davis, J.M. Hypernatremic Dehydration and Fever in Breastfed Newborns Prior to Newborn Discharge." Pediatr Res. 49(4):342A, 2001.
  • Parikh, N.A., Katsetos, C.D., Legido, A., Fritz, K.I., and Mishra, O.P. Effect of Neuronal Nitric Oxide Synthase (nNOS) Inhibition on Caspase-3 Expression During Hypoxia in the Cerebral Cortex of Newborn Piglets. Pediatr Res. 53(4):63A, 2003.
  • Parikh, N.A., Yu, X., Zhang, Y., Lasky, R.E., Datta, S., Tyson, J.E., and Narayana, P.A. Reliable and Accurate Brain Volume Segmentation in Extremely Low Birth Weight Infants. E-PAS 2009:3868.279.
  • Lasky, R.E, Parikh, N.A., Williams, A.L., Padhye, N.S., and Shankaran, S. Changes in the PQRST Intervals and Heart Rate Variability Associated with Re-warming in Two Newborns Undergoing Hypothermia Therapy. Neonatology. 2009;96:93-95 PubMed ID: 19252411
  • Parikh, N.A., Lasky, R.E., Kennedy, K.A., Moya, F.R., Hochhauser, L., Romo, S., and, Tyson, J.E. Postnatal Dexamethasone Therapy and Cerebral Tissue Volumes in Extremely Low Birth Weight Infants. Pediatrics. 2007;119(2):262-272. PubMed ID: 17272615
  • Parikh, N.A., Katsetos, C.D., Ashraf, Q.M., Haider, S.H., Legido, A., Delivoria-Papadopoulos, M., and Mishra, O.P. Hypoxia-Induced Caspase-3 Activation and DNA Fragmentation in Cortical Neurons of Newborn Piglets: Role of Nitric Oxide. Neurochem Res. 2003;28(9):1351-1357. PubMed ID: 12938857
  • Bertles, A., Parikh, N., Tyson, J.E., Blackwell, S., and Ramirez, M.M. Can ultrasound estimate of fetal weight substitute for birth weight in predicting survival at the threshold of viability? Am J Obstet Gynecol 2008 SMFM meeting supplement. Am J Obstet Gynecol. 199(6); Supplement A:734, p S209; 2008.
  • Parikh, N.A., C. Arnold, Tyson, J.E. Evidence-Based Treatment Decisions for Extremely Preterm Newborns. Pediatrics. 2010;125:813-816. PubMed ID: 20351013
  • Parikh, N.A., Tyson J.E., and the NICHD Neonatal Research Network. Viability, Treatment, and Outcome at 18-22 Months for Extremely Premature Infants. E-PAS 2006:59:5531.175.
  • Wyckoff, M.H., Parikh, N., Balachanadran, N., Moya, F., Laptook, A.R. Improved Temperature Profile Using a ThermoTek (TT) Cooling System for Induction of Hypothermia Compared to the Cincinnati Sub-Zero (CSZ). E-PAS 2006:59:443.
  • Parikh, N.A., Lasky, R.E., Bonfante-Mejia, E., Shankaran, S., and Tyson, J.E. Relationship of MRI Cerebral Tissue Volumes to Whole-Body Hypothermia Therapy for Hypoxic-Ischemic Encephalopathy and Neurosensory Outcomes. E-PAS 2008:5365.7
  • Haider, S.H., Ashraf, Q.M., Parikh, N.A., Delivoria-Papadopoulos, M., and Mishra, O.P. The Expression of Protein Tyrosine Phosphatase (PTP-1B) Following Hypoxia on Neuronal Cell Membranes of Newborn Piglets. Pediatr Res. 51(4):443A, 2002.
  • Parikh, N.A., Locke, R.G., Chidekel, A., Leef, K.H., Emberger, J., Paul, D.A., and Stefano, J.L. Effect of Inhaled Corticosteroids on Inflammatory Cytokines in Preterm Infants with Evolving Chronic Lung Disease. Pediatr Res. 51(4):356A, 2002.
  • Parikh, N.A., Lasky, R.E., Garza, C., Bonfante-Mejia, E., Shankaran, S., and Tyson, J.E. Volumetric and Anatomic MRI for Hypoxic-Ischemic Encephalopathy: Relationship to Hypothermia Therapy and Neurosensory Impairments. J Perinatol. 2008. 29(2):143-149. PubMed ID: 19020525
  • Legido, A., Parikh, N.A., Taylor, M.L., Kaleyias, J.M., de Chadarevian, J.P., and Katsetos, C.D. Decreased Immunoreactivity of Calbindin-D28K in Cerebellar Purkinje Cells of Children with Hypoxic/ Ischemic Encephalopathy. Pediatr Res. 51(4):447A, 2002.
  • Zhou, Y., Parikh, N.A., Burson, K., Narayana, P.A. 3-Tesla Cerebral Proton Magnetic Resonance Spectroscopy in Healthy Term and Extremely Preterm Infants. 2011 ISMRM Annual Meeting. Abstract 5367.
  • Parikh, N.A., Tyson J.E., and the NICHD Neonatal Research Network. Viability, Treatment, and Outcome at 18-22 Months for Extremely Premature Infants. E-PAS 2006:59:5531.175.
  • Lasky RE, Church MW, Orlando MS, Morris BH, Parikh NA, Tyson JE, McDavid GE, Oh W, Stevenson DK, Van Meurs KP, Guillet R, Phelps DL. The Effects of Aggressive Versus Conservative Phototherapy on the Brainstem Auditory Evoked Responses of Extremely Low Birth Weight Infants. Pediatr Res. 2011 In press.
  • Parikh, N.A., Locke, R.L., Paul, D.A., Chidekel, A., Leef, K., Emberger, J., and Stefano, J.L. The Effect of Inhaled Corticosteroids on Markers of Pulmonary Inflammation and Lung Maturation in Preterm Infants with Evolving Chronic Lung Disease. J Am Osteopath Assoc. 2004;104(3):114-120. PubMed ID: 15083986
  • Bertles, A., Parikh, N., Tyson, J.E., Blackwell, S., and Ramirez, M.M. Can ultrasound estimate of fetal weight substitute for birth weight in predicting survival at the threshold of viability? Am J Obstet Gynecol 2008 SMFM meeting supplement. Am J Obstet Gynecol. 199(6); Supplement A:734, p S209; 2008.
  • • Beauchamp MS, Beurlot MR, Fave E, Nath AR, Parikh NA, Saad ZS, Bortfeld H, Oghalai JS. The Developmental Trajectory of Brain-Scalp Distance from Birth through Childhood: Implications for Functional Neuroimaging. PLoS ONE. 2011;6(9): e2498.
  • Shankaran S, Pappas A, McDonald SA, Laptook AR, Bara R, Ehrenkranz RA, Tyson JE, Goldberg R, Donovan EF, Fanaroff AA, Das A, Poole WK, Walsh M, Higgins RD, Welsh C, Salhab W, Carlo WA, Poindexter B, Stoll BJ, Guillet R, Finer NN, Stevenson DK, Bauer CR; Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. [Parikh NA, UT-Houston site principal investigator]. Predictive value of an early amplitude integrated electroencephalogram and neurologic examination. Pediatrics. 2011;128(1):e112-20. PubMed ID: 21669899
  • Parikh, N.A., Katsetos, C.D., Ashraf, Q.M., Haider, S.H., Legido, A., Delivoria-Papadopoulos, M., and Mishra, O.P. Hypoxia-Induced Caspase-3 Activation and DNA Fragmentation in Cortical Neurons of Newborn Piglets: Role of Nitric Oxide. Neurochem Res. 2003;28(9):1351-1357. PubMed ID: 12938857
  • Ambalavanan, N. and GDB Subcommittee for the NICHD Neonatal Research Network. Outcome Trajectories in Extremely Low Birth Weight (ELBW) Infants. E-PAS 2009:4765.3.
  • Wyckoff, M.H., Parikh, N., Balachanadran, N., Moya, F., Laptook, A.R. Improved Temperature Profile Using a ThermoTek (TT) Cooling System for Induction of Hypothermia Compared to the Cincinnati Sub-Zero (CSZ). E-PAS 2006:59:443.
  • Lee, H.C., Green, C., Hintz, S.R., Tyson, J.E., Parikh, N.A., Langer, J., Gould, J.B. Prediction of Mortality for Extremely Premature Infants in a Population Based Cohort. Pediatrics. Sept. 2010;126(3):e644-50. PubMed ID: 20713479
  • Parikh, N.A., C. Arnold, J Langer, Tyson, J.E. Evidence-Based Treatment Decisions for Extremely Preterm Newborns. Pediatrics. 2010;125:813-816. PubMed ID: 20351013
  • Lasky, R.E., Luck, M.L., Parikh, N.A., and Laughlin, N.K. The Effects of Early Lead Exposure on the Brains of Adult Rhesus Monkeys: A Volumetric MRI Study. Toxicol Sci. 2005;85(2):963-975. PubMed ID: 15788724
  • Sorrentino DF, Fritz KI, Haider SH, Parikh N, Papadopoulos MD, Mishra OP. Nitric oxide-mediated modification of the glycine binding site of the NMDA receptor during hypoxia in the cerebral cortex of the newborn piglet. Neurochem Res. 2004;29(2):455-9. PubMed ID: 15002744
  • Tyson, J.E., Parikh, N.A., Langer, J., Green, C., Higgins, R., for the NICHD Neonatal Research Network. Intensive Care for Extreme Prematurity – Moving Beyond Gestational Age. N Engl J Med. 2008;358(16):1672-81. PubMed ID: 18420500
  • Hirsch, D., Parikh, N., and Davis, J.M. Hypernatremic Dehydration and Fever in Breastfed Newborns Prior to Newborn Discharge." Pediatr Res. 49(4):342A, 2001.
  • Parikh, N.A., Lasky, R.E., Tyson, J.E., Kennedy, K.A., Zhang, Y., and Yu, X. Does Low Dose Hydrocortisone Improve Volumetric MRI Measures of Cerebral Growth in Extremely Low Birth Weight (ELBW) Infants at High Risk for Bronchopulmonary Dysplasia (BPD)?: A Randomized Trial. E-PAS 2009:Late-Breaker Platform.
  • Ramirez, M.M., Bertles, A., Parikh, N., Blackwell, S., and Tyson, J.E. Parental wishes, resuscitation decisions, and prognostic estimates at 22-24 wks gestation. Am J Obstet Gynecol 2008 SMFM meeting supplement. Am J Obstet Gynecol. 199(6); Supplement A: 219, p S72; 2008.
  • Katsetos, C.D., Parikh, N.A., Fritz, K.I., Legido, A., Delivoria-Papadopoulos, M., and Mishra, O.P. Effect of 7-Nitroindazole Sodium on the Cellular Distribution of Neuronal Nitric Oxide Synthase in the Cerebral Cortex of Hypoxic Newborn Piglets. Neurochem Res. 2006;31(7):899-906. PubMed ID: 16804757
  • Parikh, N.A., Lasky, R.E., Garza, C., Bonfante-Mejia, E., Shankaran, S., and Tyson, J.E. Volumetric and Anatomic MRI for Hypoxic-Ischemic Encephalopathy: Relationship to Hypothermia Therapy and Neurosensory Impairments. J Perinatol. 2008. 29(2):143-149. PubMed ID: 19020525
  • Gupta, R.K., Hasan, K.M., Trivedi, R., Kanabar, B., Pradhan, M., Das, V., Parikh, N.A., and Narayana, P.A. Diffusion Tensor Imaging of the Developing Human Cerebrum. J Neurosci Res. 2005;81(2):172-178. PubMed ID: 15931676
  • Mietzsch, U., Parikh, N.A., Williams, A.L., Shankaran, S., and Lasky, R.E. Effects of Hypoxic-Ischemic Encephalopathy and Whole-Body Hypothermia on Neonatal Auditory Function: A Pilot Study. Am J of Perinatol. 2008;25(7):435-41. PubMed ID: 18720323
  • Parikh, N., Tyson, J., Kennedy, K., Yu, X., Zhang, Y., Shukla, R., Narayana, P., and Lasky, R. Perinatal Predictors of MRI Brain Volume Abnormalities at Term in Extremely Low Birth Weight (ELBW) Infants. E-PAS 2010:3746.501.
  • Parikh, N.A., Lasky, R.E., Kennedy, K.A., Moya, F.R., Hochhauser, L., Romo, S., and, Tyson, J.E. Postnatal Dexamethasone Therapy and Cerebral Tissue Volumes in Extremely Low Birth Weight Infants. Pediatrics. 2007;119(2):262-272. PubMed ID: 17272615
  • Lasky, R.E, Parikh, N.A., Williams, A.L., Padhye, N.S., and Shankaran, S. Changes in the PQRST Intervals and Heart Rate Variability Associated with Re-warming in Two Newborns Undergoing Hypothermia Therapy. Neonatology. 2009;96:93-95 PubMed ID: 19252411
  • Zhang, Y., Yu, X., Lasky, R.E., Datta, S., Parikh, N.A.*, and Narayana, P.A. Comprehensive Brain MRI Segmentation in High Risk Preterm Newborns. PLoS One. 2010;5(11): e13874. PubMed ID: 21079730

Pediacast Interview with Nehal Parikh, DO

Pediacast with Dr. Mike featuring Dr. Nehal Parikh and Megan Harrison on the topic of Breastfeeding.

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Posts by Dr. Parikh on 700 Children's

Using Brain MRI to Fight Delays in Preemies »
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