Miriam L. Freimer, MD :: Nationwide Children's Hospital, Columbus, Ohio

Miriam L. Freimer, MD

Miriam L. Freimer, MD Best Doctors 2011-2012

Neurology
Physician Team

Neurology Residency
Faculty

Neurosciences
Physician Team

Contact Information

Department of Neurology
395 W 12th Ave 7th Fl
Columbus, OH 43210 [ map ]
PH: (614) 293-4969
FX: (614) 293-6111

Biography

Gender:

  • Female

Languages Spoken:

  • English

Education and Training

Medical School

  • Ohio State University College of Medicine
    Date Completed: 06/14/1985

Residency

  • Ohio State University Wexner Medical Center
    Date Completed: 06/30/1986

Residency

  • John Hopkins Hospital
    Date Completed: 06/30/1989

Fellowship

  • John Hopkins Hospital
    Date Completed: 06/30/1992

Department:

  • Pediatrics

Section:

  • Neurology

Specialty:

  • Clinical Neurophysiology
  • Neurology
  • Neuromuscular Medicine

Date of Appointment at Nationwide Children’s Hospital:

  • 12/31/2012

Publications

  • Iyadurai,Stanley; Roggenbuck,Jennifer; Freimer,Miriam. 2015. NOVEL HISTOPATHOLOGICAL FEATURES IN A PATIENT WITH A NOVEL MUTATION IN DNAJB6 GENE (LGMD 1D LOCUS).  MUSCLE & NERVE. Vol. 52, no. September: S10-S10.
  • Schwartz, H, Fritz, J, Govindarajan, R, Penfold-Murray, R, Boyle, K, Getchius, T, Freimer, M. 2015. Neurology advanced practice providers: A position statement of the American Academy of Neurology.  Neurology: clinical practice. Vol. 5, no. August: 333-337.
  • Renton,Alan,E; Pliner,Hannah,A; Provenzano,Carlo; Evoli,Amelia; Ricciardi,Roberta; Nalls,Michael,A; Marangi,Giuseppe; Abramzon,Yevgeniya; Arepalli,Sampath; Chong,Sean; Hernandez,Dena,G; Johnson,Janel,O; Bartoccioni,Emanuela; Scuderi,Flavia; Maestri,Michelangelo; Gibbs,J,Raphael; Errichiello,Edoardo; Chio,Adriano; Restagno,Gabriella; Sabatelli,Mario; Macek,Mark; Scholz,Sonja,W; Corse,Andrea; Chaudhry,Vinay; Benatar,Michael; Barohn,Richard,J; McVey,April; Pasnoor,Mamatha; Dimachkie,Mazen,M; Rowin,Julie; Kissel,John; Freimer,Miriam; Kaminski,Henry,J; Sanders,Donald,B; Lipscomb,Bernadette; Massey,Janice,M; Chopra,Manisha; Howard,James,F; Koopman,Wilma,J; Nicolle,Michael,W; Pascuzzi,Robert,M; Pestronk,Alan; Wulf,Charlie; Florence,Julaine; Blackmore,Derrick; Soloway,Aimee; Siddiqi,Zaeem; Muppidi,Srikanth; Wolfe,Gil; Richman,David; Mezei,Michelle,M; Jiwa,Theresa; Oger,Joel; Drachman,Daniel,B; Traynor,Bryan,J. 2015. A Genome-Wide Association Study of Myasthenia Gravis.  JAMA NEUROLOGY. Vol. 72, no. 4. (April): 396-404.
  • Kissel,John,T; Elsheikh,Bakri; King,Wendy,M; Freimer,Miriam; Scott,Charles,B; Kolb,Stephen,J; Reyna,Sandra,P; Crawford,Thomas,O; Simard,Louise,R; Krosschell,Kristin,J; Acsadi,Gyula; Schroth,Mary,K; D'Anjou,Guy; LaSalle,Bernard; Prior,Thomas,W; Sorenson,Susan; Maczulski,Jo,Anne; Swoboda,Kathryn,J. 2014. SMA VALIANT TRIAL: A PROSPECTIVE, DOUBLE-BLIND, PLACEBOCONTROLLED TRIAL OF VALPROIC ACID IN AMBULATORY ADULTS WITH SPINAL MUSCULAR ATROPHY.  MUSCLE & NERVE. Vol. 49, no. 2. (February): 187-192.
  • Kissel,John,T; Elsheikh,Bakri; King,Wendy,M; Freimer,Miriam; Scott,Charles,B; Kolb,Stephen,J; Reyna,Sandra,P; Crawford,Thomas,O; Simard,Louise,R; Krosschell,Kristin,J; Acsadi,Gyula; Schroth,Mary,K; D'Anjou,Guy; LaSalle,Bernard; Prior,Thomas,W; Sorenson,Susan; Maczulski,Jo,Anne; Swoboda,Kathryn,J. 2014. SMA valiant trial: a prospective, double-blind, placebo-controlled trial of valproic acid in ambulatory adults with spinal muscular atrophy.  Muscle & nerve. Vol. 49, no. 2. (February): 187-192.
  • Arnold, W and Freimer, M. 2014. Erythromelalgia. In Color atlas and synopsis of vascular medicine. Edited by Dean, S and Satiani, B. New York City: McGraw Hill Education.
  • Howard,James,F; Barohn,Richard,J; Cutter,Gary,R; Freimer,Miriam; Juel,Vern,C; Mozaffar,Tahseen; Mellion,Michelle,L; Benatar,Michael,G; Farrugia,Maria,Elena; Wang,Jing,Jing; Malhotra,Suneil,S; Kissel,John,T. 2013. A randomized, double-blind, placebo-controlled phase II study of eculizumab in patients with refractory generalized myasthenia gravis.  MUSCLE & NERVE. Vol. 48, no. 1. (July): 76-84.
  • Elsheikh,Bakri; Arnold,William; Gharibshahi,Shahram; Reynolds,Jerold; Freimer,Miriam; Kissel,John. 2013. Correlation of Single-Breath Count Test and Neck Flexors Muscle Strength with Spirometry in Myasthenia Gravis.  NEUROLOGY. Vol. 80, no. February: es45.005.
  • Evans,Kevin,D; Roll,Shawn,C; Volz,Kevin,R; Freimer,Miriam. 2013. Nerve Blood Flow Reply.  JOURNAL OF ULTRASOUND IN MEDICINE. Vol. 32, no. 1. (January): 188-189.
  • Evans,Kevin,D; Roll,Shawn,C; Volz,Kevin,R; Freimer,Miriam. 2013. Reply.  Journal of ultrasound in medicine. Vol. 32, no. 1. (January): 188-189.
  • Arnold,W,David; Krishna,Vivek,R; Freimer,Miriam; Kissel,John,T; Elsheikh,Bakri. 2012. PROGNOSIS OF ACUTE COMPRESSIVE RADIAL NEUROPATHY.  MUSCLE & NERVE. Vol. 45, no. 6. (June): 893-895.
  • Evans,Kevin,D; Roll,Shawn,C; Volz,Kevin,R; Freimer,Miriam. 2012. Relationship Between Intraneural Vascular Flow Measured With Sonography and Carpal Tunnel Syndrome Diagnosis Based on Electrodiagnostic Testing.  JOURNAL OF ULTRASOUND IN MEDICINE. Vol. 31, no. 5. (May): 729-736.
  • Flinn,Sharon,R; Pease,William,S; Freimer,Miriam,L. 2012. Score Reliability and Construct Validity of the Flinn Performance Screening Tool for Adults With Symptoms of Carpal Tunnel Syndrome.  AMERICAN JOURNAL OF OCCUPATIONAL THERAPY. Vol. 66, no. 3. (May): 330-337.
  • Howard,James; Barohn,Richard; Freimer,Miriam; Juel,Vern; Mozaffar,Tahseen; Mellion,Michelle; Benatar,Michael; Farrugia,Maria; Kissel,John. 2012. Randomized, Double-Blind, Placebo-Controlled, Crossover, Multicenter, Phase II Study of Eculizumab in Patients with Refractory Generalized Myasthenia Gravis (gMG).  NEUROLOGY. Vol. 78, no. April.
  • Howard,James; Barohn,Richard; Freimer,Miriam; Juel,Vern; Mozaffar,Tahseen; Mellion,Michelle; Benatar,Michael; Farrugia,Maria; Kissel,John. 2012. Randomized, Double-Blind, Placebo-Controlled, Crossover, Multicenter, Phase II Study of Eculizumab in Patients with Refractory Generalized Myasthenia Gravis (gMG).  NEUROLOGY. Vol. 78, no. April: es35.004.
  • Arnold,W,David; Mongiovi,Phillip; Hoyle,J,Chad; Freimer,Miriam; Elsheikh,Bakri. 2012. Electrodiagnostic Findings Heralding Neoplastic Brachial Plexopathy.  PM&R. Vol. 4, no. 3. (March): 238-240.
  • Roll,Shawn,C; Evans,Kevin,D; Li,Xiaobai; Freimer,Miriam; Sommerich,Carolyn,M. 2011. Screening for Carpal Tunnel Syndrome Using Sonography.  JOURNAL OF ULTRASOUND IN MEDICINE. Vol. 30, no. 12. (December): 1657-1667.
  • Amato,Anthony,A; Tawil,Rabi; Kissel,John; Barohn,Richard; McDermott,Michael,P; Pandya,Shree; King,Wendy; Smirnow,Alexis; Annis,Christine; Roe,Kristen; Tawil,Rabi; McDermott,Michael,P; Janciuras,Joanne; Dilek,Nuran; Martens,William,B; Eastwood,Eileen; Amato,Anthony; Cochrane,Thomas; Donlan,Merideth; Chused,Samantha; Roe,Kristen; Barohn,Richard; Dimachkie,Mazen; Aires,Daniel,J; Latinis,Kevin,M; Herbelin,Laura; Michaels,Hiwot; Cupler,Edward; Deodhar,Atul; Simpson,Eric; Burusnukul,Prinyarat; Edgar,Eric; Serdar,Andrea; Brennan,Thomas; Gance,Kathryn; Kissel,John; Freimer,Miriam,L; Hackshaw,Kevin,V; Lawson,Victoria; King,Wendy,M; Bartlett,Amy; Wolfe,Gil; Nations,Sharon; McLin,Rhonda; Gorham,Nina; Briemberg,Hannah; Chapman,Kristine,M; Dutz,Jan,P; Wilson,Judy; Varelas,Franca; Wagner,Kathryn; Stine,Lisa,Christopher; Anhalt,Grant,James; Meyerle,Jon,H; Swain,Jennifer,O; Brock-Simmons,Regina; Weiss,Michael; Distad,B,Jane; Lin,John; Haug,Joanna,A; Downing,Sharon. 2011. A Randomized, Pilot Trial of Etanercept in Dermatomyositis The Muscle Study Group.  ANNALS OF NEUROLOGY. Vol. 70, no. 3. (September): 427-436.
  • Kolb,S,J; Snyder,P,J; Poi,E,J; Renard,E,A; Bartlett,A; Gu,S; Sutton,S; Arnold,W,D; Freimer,M,L; Lawson,V,H; Kissel,J,T; Prior,T,W. 2010. Mutant small heat shock protein B3 causes motor neuropathy Utility of a candidate gene approach.  NEUROLOGY. Vol. 74, no. 6. (February): 502-506.
  • Phatak,Kavita; Kissel,John; McCarthy,Beth; Hoyle,Chad; Freimer,Miriam; Tran,Tam; Al-Dahhak,Roula; Raman,Subha. 2009. Subclinical Myocardial Ischemia Without LV Hypertrophy in Friedreich's Ataxia.  CIRCULATION. Vol. 120, no. 18. (November): S299-S300.
  • Patel,Tanmay,R; Chiocca,E,Antonio; Freimer,Miriam,L; Christoforidis,Gregory,A. 2009. LACK OF EPIDURAL PRESSURE CHANGE WITH NECK FLEXION IN A PATIENT WITH HIRAYAMA DISEASE: CASE REPORT.  NEUROSURGERY. Vol. 64, no. 6. (June): 1196-1197.
  • Patel,Tanmay,R; Chiocca,E,Antonio; Freimer,Miriam,L; Christoforidis,Gregory,A. 2009. Lack of epidural pressure change with neck flexion in a patient with Hirayama disease: case report.  Neurosurgery. Vol. 64, no. 6. (June): E1196-7.
  • Sanders, D, Hart, I, Mantegazza, R, Shukla S, et al. 2008. An international phase III, randomized trial in mycophenylate mofetil in myasthenia gravis.  Neurology. Vol. 71, no. August: 400-406.
  • Elsheikh, B and Freimer, M. 2006. Peripheral neuropathy. In Principles and practice of Geriatric medicine. 4th ed. Edited by Pathy, MSJ. New York City: John Wiley and Sons.
  • Sahenk,Z; Nagaraja,H,N; McCracken,B,S; King,W,M; Freimer,M,L; Cedarbaum,J,M; Mendell,J,R. 2005. NT-3 promotes nerve regeneration and sensory improvement in CMT1A mouse models and in patients.  NEUROLOGY. Vol. 65, no. 5. (September): 681-689.
  • Freimer, M. 2004. Nerve conductions and electromyography. In The 5 minute neurology consult. Edited by Lynn D, Kissel J, and Newton H. Philadelphia: Lippincott Williams and wilkins.
  • Freimer, M. 2004. Carpal tunnel syndrome. In The 5 minute neurology consult. Edited by Lynn D, Kissel J and Newton H. Philadelphia: Lippincott Williams and Wilkins.
  • Chaudhry,V; Cornblath,D,R; Corse,A; Freimer,M; Simmons-O'Brien,E; Vogelsang,G. 2002. Thalidomide-induced neuropathy.  NEUROLOGY. Vol. 59, no. 12. (December): 1872-1875.
  • Wolfe,G,I; Barohn,R,J; Foster,B,M; Jackson,C,E; Kissel,J,T; Day,J,W; Thornton,C,A; Nations,S,P; Bryan,W,W; Amato,A,A; Freimer,M,L; Parry,G,J; Mendell,J,R. 2002. Randomized, controlled trial of intravenous immunoglobulin in myasthenia gravis.  MUSCLE & NERVE. Vol. 26, no. 4. (October): 549-552.
  • Wolfe, G, Barohn, R, Foster, B, Jackson, C, Kissel, JT, Day, J, THornton, C, Nations, S, Bryan, W, Amato, A, Freimer, M et al. 2002. Randomized controlled trial of intravenous immunoglobulin in myasthenia gravis.  Muscle and Nerve. Vol. 26, no. October: 549-552.
  • Novak,V; Freimer,M,L; Kissel,J,T; Sahenk,Z; Periquet,I,M; Nash,S,M; Collins,M,P; Mendell,J,R. 2001. Autonomic impairment in painful neuropathy.  NEUROLOGY. Vol. 56, no. 7. (April): 861-868.
  • Mendell, J, Barohn, R, Freimer, M et al. 2001. Randomized controlled trial of IVIG in untreated chronic demyelinating polyradiculoneuropathy.  Neurology. Vol. 56, no. February: 445-449.
  • Freimer, ML, Brushart T, Cornblath D, and Kissel J. 2001. Entrapment neuropathies. In Peripheral neuropathy. Edited by mendell, J, Kissel J, and Cornblath D. Oxford: Oxford University press.
  • Apfel, S, Schwartz, S, Adornato, B et al. 2000. Efficacy and safety of recombinant human nerve growth factor in patients with diabetic polyneuropathy: a randomized controlled trial.  JAMA. Vol. 284, no. November: 2215-2221.
  • McArthur, J, Yiannoutsos, C, Simpson, D et al. 2000. A phase II trial of nerve growth factor for sensory neuropathy associated with HIV infection.  Neurology. Vol. 54, no. March: 1080-1088.
  • Periquet,M,I; Novak,V; Collins,M,P; Nagaraja,H,N; Erdem,S; Nash,S,M; Freimer,M,L; Sahenk,Z; Kissel,J,T; Mendell,J,R. 1999. Painful sensory neuropathy - Prospective evaluation using skin biopsy.  NEUROLOGY. Vol. 53, no. 8. (November): 1641-1647.
  • Periquet,M, Novak, V, Collins, M, Nagaraja, H, Erdem, S, Nash, S, Freimer, M, Shanek, Z Kissel,J, Mendell,J. 1999. Painful sensory neuropathy:prospective evaluation using skin biopsy.  NEUROLOGY. Vol. 53, no. November: 1641-47.
  • Novak,V; Periquet,I; Kissel,J; Freimer,M; Nash,S; Sahenk,Z; Collins,M; Mendell,J. 1999. The role of autonomic testing in painful sensory neuropathy.  NEUROLOGY. Vol. 52, no. 6. (April): A389-A389.
  • Periquet,I; Mendell,J; Freimer,M; Kissel,J; Nash,S; Novak,V. 1998. Autonomic impairment in distal small fiber neuropathy.  ANNALS OF NEUROLOGY. Vol. 44, no. 3. (September): 475-475.
  • Sahenk,Z; Chen,L; Freimer,M. 1998. A novel PMP22 point mutation causing HNPP phenotype - Studies on nerve xenografts.  NEUROLOGY. Vol. 51, no. 3. (September): 702-707.
  • Chen,L; Freimer,F; Sahenk,Z. 1998. A novel Val30Met PMP22 mutation causes HNPP.  NEUROLOGY. Vol. 50, no. 4. (April): A72-A73.
  • Erdem, S, Freimer, M, O'Dorisio, T, Mendell, J. 1998. Procainamide-induced chronic inflammatory demyelinating polyradiculoneuropathy.  Neurology. Vol. 50, no. March: 824-825.
  • Freimer, M. 1998. Peripheral neuropathy. In Principles and practice of geriatric medicine. 3rd ed. Edited by Pathy, MSJ. New York: JOhn Wiley.
  • Archer, T, Freimer, M, Mazzaferri E. 1997. Chronic fatigue and acute respiratory failure in a house painter.  Hospital practice. Vol. 32, no. September: 150-155.
  • Chaudhry,V; Cornblath,D; Corse,A; Freimer,M; SIMMONSOBRIEN,E; Vogelsang,G. 1996. Thalidomide-induced neuropathy: Clinical and electrophysiological features.  NEUROLOGY. Vol. 46, no. 2. (February): 27003-27003.
  • Nadkarni N, Freimer, M, Mendell, J. 1995. Amyloidosis causing a progressive myopathy.  Muscle and Nerve. Vol. 18, no. September: 1016-1018.
  • Chaudhry,V; Corse,A,M; Freimer,M,L; Glass,J,D; MELLITS,E,D; Kuncl,R,W; Quaskey,S,A; Cornblath,D,R. 1995. NERVE-CONDUCTION STUDIES IN DIABETIC NEUROPATHY - REPLY.  NEUROLOGY. Vol. 45, no. 4. (April): 849-850.
  • Chaudhry, V, Corse, A, Freimer, M et al. 1994. Inter- and Intra- examiner reliability of nerve conduction measurements in patients with diabetic neuropathy.  Neurology. Vol. 44, no. August: 1459-1462.
  • Chaudhry,V; Corse,A,M; Cornblath,D,R; Kuncl,R,W; Freimer,M,L; Griffin,J,W. 1994. MULTIFOCAL MOTOR NEUROPATHY - ELECTRODIAGNOSTIC FEATURES.  MUSCLE & NERVE. Vol. 17, no. 2. (February): 198-205.
  • Freimer, M and Cornblath, D. 1994. Peripheral nerve disorders in the elderly. In Clinical neurology of aging. Edited by Albert, M and Knoefel, J. Oxford: Oxford University Press.
  • Freimer, M, McIntosh, K, Adams, R, Alving, C, Drachman, D. 1993. Gangliosides elicit a Tcell independent antibody response.  Journal of Autoimmunity. Vol. 6, no. June: 281-289.
  • Chaudhry,V; Corse,A,M; Cornblath,D,R; Kuncl,R,W; Drachman,D,B; Freimer,M,L; MILLER,R,G; Griffin,J,W. 1993. MULTIFOCAL MOTOR NEUROPATHY - RESPONSE TO HUMAN IMMUNE GLOBULIN.  ANNALS OF NEUROLOGY. Vol. 33, no. 3. (March): 237-242.
  • Gilbert, M and Freimer M. 1993. Neurotoxicity of cytotoxic agents. In Current therapy in neurollgic disease. 4th ed. Edited by JOhnson, R and Griffin J. Hamilton, ON: BC Decker Press.
  • Freimer,M,L; Glass,J,D; Chaudhry,V; Tyor,W,R; Cornblath,D,R; Griffin,J,W; Kuncl,R,W. 1992. CHRONIC DEMYELINATING POLYNEUROPATHY ASSOCIATED WITH EOSINOPHILIA-MYALGIA-SYNDROME.  JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY. Vol. 55, no. 5. (May): 352-358.
  • Traboulsi E, Maumenee I, Green W, Freimer, M and MOser, H. 1992. Olivopontocerebellaratrophy with reitnal degenertion.  Archives of Ophthamology. Vol. 106, no. May: 801-806.
  • Chaudhry,V; Cornblath,D,R; MELLITS,E,D; Avila,O; Freimer,M,L; Glass,J,D; Reim,J; Ronnett,G,V; Quaskey,S,A; Kuncl,R,W. 1991. INTER-EXAMINER AND INTRA-EXAMINER RELIABILITY OF NERVE-CONDUCTION MEASUREMENTS IN NORMAL SUBJECTS.  ANNALS OF NEUROLOGY. Vol. 30, no. 6. (December): 841-843.
  • ABUSHAKRA,S,R; Cornblath,D,R; AVILA,O,L; Chaudhry,V; Freimer,M; Glass,J,D; REIM,J,W; Ronnett,G,V. 1991. CONDUCTION BLOCK IN DIABETIC NEUROPATHY.  MUSCLE & NERVE. Vol. 14, no. 9. (September): 858-862.
  • ABUSHAKRA,S,R; Cornblath,D,R; Avila,O; Chaudhry,V; Freimer,M; Glass,J; Reim,J; Ronnett,G. 1990. CONDUCTION BLOCK IN DIABETIC NEUROPATHY.  MUSCLE & NERVE. Vol. 13, no. 9. (September): 866-866.
  • Waldron, I, Nowotarski, M , Freimer, M et al. 1982. Cross cultural variation in blood pressure: a quantitative analysis of the relationship of blood pressure to cultural characteristics, salt consumption, and body weight.  Social science and medicine. Vol. 6, no. April: 419-436.
  • Waldron,I; NOWOTARSKI,M; Freimer,M; Henry,J,P; Post,N; Witten,C. 1982. CROSS-CULTURAL VARIATION IN BLOOD-PRESSURE - A QUANTITATIVE-ANALYSIS OF THE RELATIONSHIPS OF BLOOD-PRESSURE TO CULTURAL-CHARACTERISTICS, SALT CONSUMPTION AND BODY-WEIGHT.  SOCIAL SCIENCE & MEDICINE. Vol. 16, no. 4. (January): 419-430.
  • Elsheikh, B, Arnold, WD, Garibshahi, S, Reynolds, J, Freimer, M, and Kissel, J. Correlation of single breath count test and neck flexor muscle strength with spirometry in myasthenia gravis.  Muscle and Nerve.
  • Elsheikh, B, Arnold, W, Gharibshahi, S, Reynolds, J, Freimer, M, and Kissel, J. Correlation of single-breath count test and neck flexor muscle strength with spirometry in myasthenia gravis.  Muscle and Nerve.
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